Rare Disease Business Manager Jobs in USA with Visa Sponsorship
Rare Disease Business Managers lead commercial strategy for specialty therapeutics, a field where employers routinely sponsor H-1B visa and O-1 visas for candidates with biotech or pharma backgrounds. Competition for qualified talent is tight enough that sponsorship is common, even for mid-level roles. For detailed occupation requirements, see the O*NET profile.
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Job Description
Rare Disease Business Manager – PI / CIDP
Takeda Pharmaceutical
USA – Omaha, NE
Are you looking for a patient-focused, innovative-driven company to inspire you and empower you? Join us as a Rare Disease Business Manager – Primary Immune Deficiency and CIDP supporting Iowa and Omaha, NE.
At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a value-led company. To do this, we empower our people to realize their potential through life-changing work. As part of the PI/CIDP Sales Team, you will report to the Sr. Regional Business Director.
How you will contribute:
- Achieve sales quotas through driving new patient starts, sales in outpatient infusion centers and hospitals, and retention of patients on Takeda augmentation treatment.
- Conduct customer engagements to deliver sales presentations, provide technical and administrative product information, and educate on neuromuscular conditions and various Takeda support resources.
- Understand influence points within the office and how each individual affects diagnosis, treatment, and the Rx/referral/order.
- Participate in community education events and conferences for healthcare professionals and patients.
- Focus on healthcare professionals (Allergy/Immunology, Pulmonology, Infectious Disease, select Internal Medicine/Primary Care and Neurologists). Educate and inform the HCPs on Takeda brands for Primary Immune Deficiency and CIDP.
- Analyze local and regional business/managed markets trends to build both long and short terms goals that lead to a successful business plan.
- Collaborate with multiple teams (Marketing, Patient Services, Alternate Site Team, Integrated Health Systems, Market Access, and National Accounts) to ensure high levels of customer satisfaction and pull through opportunities within each geography.
- Work compliantly in a matrix environment encompassing Patient Services, Specialty Infusion Pharmacies, and Managed Markets, which includes treating confidential patient information in accordance with Takeda practices and policies.
- Embody and embrace the patient-centric culture aligned to our values of Takeda-ism and follow PTRB (patient, trust, reputation, business) as a guide in decision making.
KEY SKILLS
- Excellent organizational and territory planning abilities.
- Proven success as both a team player, independent contributor and collaborating in a matrixed organization to enhance business outcomes.
- Skilled in data acquisition and interpretation to develop effective sales strategies.
- Conduct community education events for healthcare professionals, patients, and can work occasional nights and weekends.
- Partners with and motivates extended team members to improve performance, fostering a culture of engagement and accountability.
Expected skills (minimum education, knowledge or experience required to be successful in role)
Required:
- Bachelor’s degree – BS/BA.
- 3+ years of successful selling experience in pharmaceutical, biotech or medical device and/or relevant clinical or industry experience; OR 2+ years of successful selling experience at Takeda.
- Excellent verbal and written communication skills.
- Proven ability to navigate complex selling environment and influence across various decision makers in key accounts.
- Strong business acumen and strategic planning skills to identify and execute on selling opportunities.
- Demonstrated territory planning, strategic account management and prioritization skills. Ability to interpret analytical data to create effective sales strategies.
- Strong collaborative skills and ability to work within a matrix of cross functional partners on behalf of the customers served.
- Understanding of payer access and reimbursement at territory, regional, and state levels.
- Adaptability to changing market conditions and customer needs.
- Demonstrated learning agility with ability to successfully develop and compliantly apply clinical expertise and selling skills.
- Must reside within the territory or assigned geography.
Preferred:
- 5+ years of pharmaceutical sales experience, preferably in rare disease.
- Sales experience with pharmaceutical or biologic products requiring coordination with patient access and market access teams.
- Relevant clinical or industry experience.
- Consultative / needs-based selling skills.
- Experience working in a highly regulated marketplace.
- Adept at leveraging emerging technologies, digital tools, and openness to AI-enabled processes.
LICENSES/CERTIFICATIONS:
Valid Driver's License
TRAVEL REQUIREMENTS:
- Ability to drive and/or fly to accounts and occasional business meetings.
- Some overnight travel of up to 25-50% may be required depending on geographic assignment.
TRAINING REQUIREMENTS:
- This position and continued employment is contingent upon the employee successfully passing mandatory product training which includes written and oral examinations.
- External Takeda Hires Only: During that training period, the employee will be classified as a non-exempt employee and will be eligible for overtime during the training period only in accordance with applicable federal and/or state law but the employee will not be eligible for any Takeda related sales incentive programs and/or other production based bonuses. The training period will consist of live instruction, independent study, role play, and other training related activities which should take no more than 8 hours per day and 40 hours total in a workweek.
- After successful passage of the mandatory product training examinations, the employee will be transitioned to exempt status and will no longer be eligible for overtime. They will then be paid on a bi-weekly basis and eligible to participate in various Takeda related sales incentive programs and/or contests.
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
State of Iowa and Omaha, NE
U.S. Hourly Wage Range:
$66.11 - $90.91
The estimated hourly wage range reflects an anticipated range for this position. The actual hourly wage offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual hourly wage offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Locations
Iowa - Virtual
Worker Type
Employee
Worker Sub-Type
Regular
Time Type
Full time
Job Exempt
No
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
LI-Remote
More about us:
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
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Get Access To All JobsTips for Finding Visa Sponsorship as a Rare Disease Business Manager
Target biotech and rare disease specialty pharma employers
Companies like Sanofi Genzyme, BioMarin, and Alexion have established immigration programs and routinely sponsor H-1B visas for commercial roles. Smaller rare disease biotechs often sponsor too, especially when filling niche therapeutic area expertise.
Lead with your rare disease or orphan drug experience
Employers justify H-1B specialty occupation status more easily when your background directly matches the therapeutic area. Patient advocacy experience, KOL relationships, and payer access knowledge in rare disease make your sponsorship case significantly stronger.
Understand how your degree field affects your petition
H-1B approval requires a degree in a field directly related to the role. Life sciences, pharmacy, health economics, or business degrees with biotech concentration typically satisfy this. A general business degree alone may require additional documentation.
Ask about sponsorship early, but frame it as logistics, not a red flag
Bring up visa sponsorship after demonstrating your value, ideally in the second interview or offer stage. Frame it as a straightforward process your previous employers have navigated, not as a complication requiring special consideration from the hiring team.
Consider O-1A if your rare disease track record is strong
If you have publications, speaker engagements, rare disease awards, or a history of leading high-impact launches, the O-1A visa may be worth exploring. It bypasses the H-1B lottery and is approved at higher rates for demonstrably accomplished candidates.
Use Migrate Mate to filter specifically for sponsoring employers
Not every job posting that sounds like a match will offer sponsorship. Migrate Mate surfaces roles from employers with active visa sponsorship histories, so you spend your time on opportunities that are actually accessible given your immigration situation.
Rare Disease Business Manager jobs are hiring across the US. Find yours.
Find Rare Disease Business Manager JobsFrequently Asked Questions
Can a Rare Disease Business Manager role qualify for H-1B sponsorship?
Yes, provided the employer can demonstrate the position requires a bachelor's degree or higher in a specific specialty. Rare Disease Business Manager roles typically qualify because they require specialized knowledge in life sciences, health economics, or pharmaceutical commercialization. USCIS scrutinizes business roles more than clinical ones, so a well-documented job description and a degree in a directly related field strengthen the petition considerably.
Which visa types are most relevant for this role?
The H-1B is the most common path, particularly for candidates already in the U.S. on OPT or another nonimmigrant status. The O-1A is worth considering if you have a strong record of rare disease launches, speaking engagements, or peer-reviewed contributions. Australians may qualify for the E-3, which has no lottery and faster processing. Browse currently open roles on Migrate Mate to see which visa types sponsoring employers in this space support.
Does my degree field matter for getting sponsored in this role?
It matters significantly. USCIS requires that the offered position qualifies as a specialty occupation and that your degree is in a field directly related to it. Life sciences, pharmaceutical sciences, health economics, public health, and business degrees with biotech or healthcare concentration are the strongest fits. A general MBA or unrelated bachelor's degree may require additional evidence, such as advanced coursework or professional certifications, to support the specialty occupation argument.
How selective are rare disease pharma companies about sponsoring commercial roles?
Selectivity varies by company size and pipeline stage. Established rare disease companies with large commercial teams, such as those focused on enzyme replacement therapies or gene therapies, have mature HR and legal infrastructure for sponsorship. Earlier-stage biotechs may sponsor on a case-by-case basis when the candidate has a specific therapeutic area background they cannot easily hire domestically. Your leverage increases when you bring existing payer relationships, patient advocacy networks, or formulary access experience in the specific disease area.
What happens to my visa status if the rare disease product I'm hired to commercialize gets a setback?
Your H-1B status is tied to the employer, not the specific product. If the company restructures your role rather than terminating you, your status generally remains valid as long as you maintain a qualifying position. If you're laid off, you have a 60-day grace period to find a new sponsoring employer, change status, or depart. Some rare disease biotechs include severance provisions that account for immigration status, so it's worth clarifying this before accepting an offer.
What is the prevailing wage requirement for sponsored Rare Disease Business Manager jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.
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