Rare Disease Business Manager Jobs in USA with Visa Sponsorship
Rare Disease Business Managers lead commercial strategy for specialty therapeutics, a field where employers routinely sponsor H-1B visa and O-1 visas for candidates with biotech or pharma backgrounds. Competition for qualified talent is tight enough that sponsorship is common, even for mid-level roles. For detailed occupation requirements, see the O*NET profile.
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Get Access To All JobsBy clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.
Job Description
Are you looking for a patient-focused, innovation-driven company to inspire you and empower you to shine? Join us as a Rare Disease Business Manager – Alpha-1 supporting Charleston SC, Myrtle Beach SC, Columbia SC, Augusta GA including Savannah, GA and various areas in between.
At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work.
As part of the Alpha I Sales Team, you will report to the Regional Business Leader.
How you will contribute:
- The Rare Disease Business Manager (RDBM) will achieve sales quotas through driving new patient starts, sales in outpatient infusion centers and hospitals, and retention of patients on Takeda augmentation treatment.
- These efforts occur through a focus on healthcare professionals (Pulmonology, Allergy/Immunology, Respiratory Therapists, select Internal Medicine/Primary Care). Educate and inform the HCPs on Takeda brands for Alpha-1 Antitrypsin Deficiency. You will build the National Sales and Marketing Strategy in a compliant manner while creating a territory business tactical plan to maximize opportunity.
- Calls on prospective customers, masters sales presentations, provides technical and administrative product information and demonstrations, and maintains compliance to our promotional and expense policies.
- You will work in partnership with home office personnel, the Marketing/Brand team, and the National and Corporate account teams for pull-through of product sales.
- TBM Alpha-1 will use Microsoft applications and Takeda's customer management system.
- Conduct community education events for healthcare professionals, patients, and can work occasional nights and weekends.
- Promote the Takeda Culture through positive ongoing relationships and activities.
Minimum Requirements/Qualifications:
- Clinical sales background with a Bachelor's degree (minimum).
- 3+ years of successful selling experience in pharmaceutical, biotech or medical device and/or relevant clinical or industry experience; OR 2+ years of successful selling experience at Takeda.
- RDBM will live within territory and manage territory from Border-to-Border.
- Work within the organization, with patient services, customer service, marketing, market access, contracts, national accounts, hospital team, and operations.
- Understanding of customers motivations and needs.
- Organizational, and territory planning skills.
- Experience working with payor and reimbursement challenges.
- Successful ability to excel both in team and individual contributor settings.
- Effective at acquiring and interpreting data to create sales strategies.
- Results in influencing HCPs (Health Care Professionals) to prescribe.
- Experience with specialty biologics (injections/infusions) and working with specialty pharmacies preferred.
- Knowledge of and experience in Plasma Derived Therapies, Rare diseases, or Biotech is desirable.
- Exact amount of travel required is based on territory size and customer locations, overnight travel could be ~50%. Remaining time will be local travel and may require occasional weekends.
- Must be 18 years of age or older with valid driver's license and an acceptable driving record.
- Must have authorization and ability to drive a company leased vehicle or rental.
What Takeda can offer you:
- Comprehensive Healthcare: Medical, Dental, and Vision.
- Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan.
- Health & Wellness programs including onsite flu shots and health screenings.
- Generous time off for vacation and the option to purchase additional vacation days.
- Community Outreach Programs and company match of charitable contributions.
- Family Planning Support.
- Flexible Work Paths.
- Tuition reimbursement.
TRAVEL REQUIREMENTS:
- Ability to drive and/or fly to accounts and occasional business meetings.
- Some overnight travel of up to 25-50% may be required depending on geographic assignment.
TRAINING REQUIREMENTS:
This position and continued employment is contingent upon the employee successfully passing mandatory product training which includes written and oral examinations.
External Takeda Hires Only: During that training period, the employee will be classified as a non-exempt employee and will be eligible for overtime during the training period only in accordance with applicable federal and/or state law but the employee will not be eligible for any Takeda related sales incentive programs and/or other production based bonuses. The training period will consist of live instruction, independent study, role play, and other training related activities which should take no more than 8 hours per day and 40 hours total in a workweek.
After successful passage of the mandatory product training examinations, the employee will be transitioned to exempt status and will no longer be eligible for overtime. They will then be paid on a bi-weekly basis and eligible to participate in various Takeda related sales incentive programs and/or contests.
More about us:
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
USA - SC - Virtual
U.S. Hourly Wage Range:
$63.51 - $87.31
The estimated hourly wage range reflects an anticipated range for this position. The actual hourly wage offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual hourly wage offered will be in accordance with state or local minimum wage requirements for the job location.
For information about our benefits, please click here.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Locations
USA - SC - Virtual
Worker Type
Employee
Worker Sub-Type
Regular
Time Type
Full time
Job Exempt
No
LI-Remote
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.
Job Description
Are you looking for a patient-focused, innovation-driven company to inspire you and empower you to shine? Join us as a Rare Disease Business Manager – Alpha-1 supporting Charleston SC, Myrtle Beach SC, Columbia SC, Augusta GA including Savannah, GA and various areas in between.
At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work.
As part of the Alpha I Sales Team, you will report to the Regional Business Leader.
How you will contribute:
- The Rare Disease Business Manager (RDBM) will achieve sales quotas through driving new patient starts, sales in outpatient infusion centers and hospitals, and retention of patients on Takeda augmentation treatment.
- These efforts occur through a focus on healthcare professionals (Pulmonology, Allergy/Immunology, Respiratory Therapists, select Internal Medicine/Primary Care). Educate and inform the HCPs on Takeda brands for Alpha-1 Antitrypsin Deficiency. You will build the National Sales and Marketing Strategy in a compliant manner while creating a territory business tactical plan to maximize opportunity.
- Calls on prospective customers, masters sales presentations, provides technical and administrative product information and demonstrations, and maintains compliance to our promotional and expense policies.
- You will work in partnership with home office personnel, the Marketing/Brand team, and the National and Corporate account teams for pull-through of product sales.
- TBM Alpha-1 will use Microsoft applications and Takeda's customer management system.
- Conduct community education events for healthcare professionals, patients, and can work occasional nights and weekends.
- Promote the Takeda Culture through positive ongoing relationships and activities.
Minimum Requirements/Qualifications:
- Clinical sales background with a Bachelor's degree (minimum).
- 3+ years of successful selling experience in pharmaceutical, biotech or medical device and/or relevant clinical or industry experience; OR 2+ years of successful selling experience at Takeda.
- RDBM will live within territory and manage territory from Border-to-Border.
- Work within the organization, with patient services, customer service, marketing, market access, contracts, national accounts, hospital team, and operations.
- Understanding of customers motivations and needs.
- Organizational, and territory planning skills.
- Experience working with payor and reimbursement challenges.
- Successful ability to excel both in team and individual contributor settings.
- Effective at acquiring and interpreting data to create sales strategies.
- Results in influencing HCPs (Health Care Professionals) to prescribe.
- Experience with specialty biologics (injections/infusions) and working with specialty pharmacies preferred.
- Knowledge of and experience in Plasma Derived Therapies, Rare diseases, or Biotech is desirable.
- Exact amount of travel required is based on territory size and customer locations, overnight travel could be ~50%. Remaining time will be local travel and may require occasional weekends.
- Must be 18 years of age or older with valid driver's license and an acceptable driving record.
- Must have authorization and ability to drive a company leased vehicle or rental.
What Takeda can offer you:
- Comprehensive Healthcare: Medical, Dental, and Vision.
- Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan.
- Health & Wellness programs including onsite flu shots and health screenings.
- Generous time off for vacation and the option to purchase additional vacation days.
- Community Outreach Programs and company match of charitable contributions.
- Family Planning Support.
- Flexible Work Paths.
- Tuition reimbursement.
TRAVEL REQUIREMENTS:
- Ability to drive and/or fly to accounts and occasional business meetings.
- Some overnight travel of up to 25-50% may be required depending on geographic assignment.
TRAINING REQUIREMENTS:
This position and continued employment is contingent upon the employee successfully passing mandatory product training which includes written and oral examinations.
External Takeda Hires Only: During that training period, the employee will be classified as a non-exempt employee and will be eligible for overtime during the training period only in accordance with applicable federal and/or state law but the employee will not be eligible for any Takeda related sales incentive programs and/or other production based bonuses. The training period will consist of live instruction, independent study, role play, and other training related activities which should take no more than 8 hours per day and 40 hours total in a workweek.
After successful passage of the mandatory product training examinations, the employee will be transitioned to exempt status and will no longer be eligible for overtime. They will then be paid on a bi-weekly basis and eligible to participate in various Takeda related sales incentive programs and/or contests.
More about us:
At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.
Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location:
USA - SC - Virtual
U.S. Hourly Wage Range:
$63.51 - $87.31
The estimated hourly wage range reflects an anticipated range for this position. The actual hourly wage offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual hourly wage offered will be in accordance with state or local minimum wage requirements for the job location.
For information about our benefits, please click here.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Locations
USA - SC - Virtual
Worker Type
Employee
Worker Sub-Type
Regular
Time Type
Full time
Job Exempt
No
LI-Remote
See all 148+ Rare Disease Business Manager Jobs
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Get Access To All JobsTips for Finding Visa Sponsorship as a Rare Disease Business Manager
Target biotech and rare disease specialty pharma employers
Companies like Sanofi Genzyme, BioMarin, and Alexion have established immigration programs and routinely sponsor H-1B visas for commercial roles. Smaller rare disease biotechs often sponsor too, especially when filling niche therapeutic area expertise.
Lead with your rare disease or orphan drug experience
Employers justify H-1B specialty occupation status more easily when your background directly matches the therapeutic area. Patient advocacy experience, KOL relationships, and payer access knowledge in rare disease make your sponsorship case significantly stronger.
Understand how your degree field affects your petition
H-1B approval requires a degree in a field directly related to the role. Life sciences, pharmacy, health economics, or business degrees with biotech concentration typically satisfy this. A general business degree alone may require additional documentation.
Ask about sponsorship early, but frame it as logistics, not a red flag
Bring up visa sponsorship after demonstrating your value, ideally in the second interview or offer stage. Frame it as a straightforward process your previous employers have navigated, not as a complication requiring special consideration from the hiring team.
Consider O-1A if your rare disease track record is strong
If you have publications, speaker engagements, rare disease awards, or a history of leading high-impact launches, the O-1A visa may be worth exploring. It bypasses the H-1B lottery and is approved at higher rates for demonstrably accomplished candidates.
Use Migrate Mate to filter specifically for sponsoring employers
Not every job posting that sounds like a match will offer sponsorship. Migrate Mate surfaces roles from employers with active visa sponsorship histories, so you spend your time on opportunities that are actually accessible given your immigration situation.
Frequently Asked Questions
Can a Rare Disease Business Manager role qualify for H-1B sponsorship?
Yes, provided the employer can demonstrate the position requires a bachelor's degree or higher in a specific specialty. Rare Disease Business Manager roles typically qualify because they require specialized knowledge in life sciences, health economics, or pharmaceutical commercialization. USCIS scrutinizes business roles more than clinical ones, so a well-documented job description and a degree in a directly related field strengthen the petition considerably.
Which visa types are most relevant for this role?
The H-1B visa is the most common path, particularly for candidates already in the U.S. on OPT or another nonimmigrant status. The O-1A is worth considering if you have a strong record of rare disease launches, speaking engagements, or peer-reviewed contributions. Australians may qualify for the E-3 visa, which has no lottery and faster processing. Browse currently open roles on Migrate Mate to see which visa types sponsoring employers in this space support.
Does my degree field matter for getting sponsored in this role?
It matters significantly. USCIS requires that the offered position qualifies as a specialty occupation and that your degree is in a field directly related to it. Life sciences, pharmaceutical sciences, health economics, public health, and business degrees with biotech or healthcare concentration are the strongest fits. A general MBA or unrelated bachelor's degree may require additional evidence, such as advanced coursework or professional certifications, to support the specialty occupation argument.
How selective are rare disease pharma companies about sponsoring commercial roles?
Selectivity varies by company size and pipeline stage. Established rare disease companies with large commercial teams, such as those focused on enzyme replacement therapies or gene therapies, have mature HR and legal infrastructure for sponsorship. Earlier-stage biotechs may sponsor on a case-by-case basis when the candidate has a specific therapeutic area background they cannot easily hire domestically. Your leverage increases when you bring existing payer relationships, patient advocacy networks, or formulary access experience in the specific disease area.
What happens to my visa status if the rare disease product I'm hired to commercialize gets a setback?
Your H-1B status is tied to the employer, not the specific product. If the company restructures your role rather than terminating you, your status generally remains valid as long as you maintain a qualifying position. If you're laid off, you have a 60-day grace period to find a new sponsoring employer, change status, or depart. Some rare disease biotechs include severance provisions that account for immigration status, so it's worth clarifying this before accepting an offer.
What is the prevailing wage requirement for sponsored Rare Disease Business Manager jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.