AI Data Engineer Jobs in Minnesota
AI Data Engineer jobs in Minnesota are concentrated in the Twin Cities metro, Rochester, and Duluth, where employers like Target, UnitedHealth Group, and Mayo Clinic maintain large data engineering teams. Demand is strongest for engineers with expertise in machine learning pipelines, large language model integration, and cloud-native data infrastructure. The market supports roles from entry-level analysts stepping into AI-focused positions to senior architects leading enterprise data strategy. Scan the live roles below and apply to whichever ones fit.
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CityRochester
StateMN
RemoteNO
DepartmentInformation Technology
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
Responsibilities
Data Scientists at Mayo Clinic perform detailed analysis of large bodies of heterogeneous healthcare data, including imaging, genomics, clinical text, structured EHR data, signals, and other healthcare modalities to discover new patterns and insights having an impact upon patient health and augmenting human capabilities. Candidate has deep expertise in AI, machine learning, deep learning, multimodal model development, statistical data processing, regression techniques, neural networks, decision trees, clustering, pattern recognition, probability theory and data science methods and the mathematical theories underlying these tools used to analyze data. Has deep knowledge of healthcare data types, modalities, topics, and scientific challenges, including how large language models and multimodal foundation models are built, adapted, evaluated, and safely applied in healthcare settings.
May work with knowledge architects, informaticians and clinicians at Mayo, and partner outside companies to develop and deploy applications to bring AI, foundation model and analytic solutions to nontechnical users, often at the point of care. Applies and modifies existing scripts or software applications to support data management, data extraction, data analysis, and AI as required
May develop predictive models on large-scale datasets to address various business problems through leveraging advanced statistical modeling, operations research, machine learning, or data mining techniques. May provide Consultative Services at an enterprise level to departments/divisions and/or support scientific projects under the supervision of a designated senior level data scientist.
Other responsibilities:
- Applies analytics techniques to extract insights from structured, unstructured, and multimodal healthcare data, including text, imaging, genomics, and other clinical data types.
- Develops predictive, prescriptive, generative, and multimodal models to address complex healthcare problems, discover insights, and identify opportunities using machine learning, statistical techniques, data mining, and foundation model approaches.
- Will work with other staff in developing data analysis tools and predictive models, using advanced data analysis techniques and artificial intelligence and machine learning.
- Participates in discovery processes with stakeholders to identify the business requirements and the expected outcome.
- Supports the use and adaptation of algorithms and models, including machine learning, LLM, and multimodal approaches, to identify patterns across healthcare data modalities.
- Applies working knowledge of LLMs and foundation models to support prompting, evaluation, and safe use in healthcare applications.
- Leads the interpretation of data analysis and writing reports.
Qualifications
A Bachelor’s degree in a relevant field such as engineering, mathematics, computer science, health science and at least 12 graduate level semester hours in domain-relevant sciences or seven years or more of data science and AI experience.
The preferred candidate will possess a PhD or Master’s degree with one year experience in a relevant field such as engineering, mathematics, computer science, health science, or other analytical/quantitative field and a minimum of one year of professional or research experience in data.
The successful candidate will need to have both technical and business background/experience along with strong leadership skills. Good written and oral communication skills are required. Expertise in the use of scientific computing and data management packages. Ability to prioritize, organize, and delegate various tasks on projects. Demonstrated initiative in administration, education (seminars, training), software development, and technical reports. Demonstrated success in project management and communication skills. Demonstrated ability to develop predictive and prescriptive models on large-scale datasets to address various business problems through leveraging advanced statistical modeling, machine learning, or data mining techniques. Demonstrated ability to provide consultative services to departments/divisions and committees from any Mayo entity requesting assistance is preferred. Demonstrated application of several problem-solving methodologies, planning techniques, continuous improvement methods, project management methods, and analytical tools and methodologies (e.g. machine learning, statistical packages, modeling, etc.) required. Incumbent must have ability to manage a varied workload of projects with multiple priorities and stay current on healthcare trends and enterprise changes. Strong interpersonal skills to include presentation, negotiation, persuasion, and written communications skills are required. Strong time management skills also are required. In addition, requires strong analytical skills, consulting skills, ability to identify and recommend solutions, advanced computer application skills and a commitment to customer service. Experience with data modeling and date exploration tools.
The preferred candidate will possess:
- Expertise in AI/ML techniques and frameworks, such as deep learning, natural language processing, computer vision, multimodal AI, representation learning, and Generative AI, with proficiency in tools like Python, TensorFlow, PyTorch, sci-kit-learn, Keras, etc.
- Experience with healthcare industry informatics standards, best practices, and common data models
- Strong communication, collaboration, and stakeholder management skills, with the ability to effectively engage with diverse stakeholders and translate complex technical concepts and results to non-technical audiences.
- Experience participating in cross functional teams in a regulated environment.
- Strong problem-solving abilities, critical thinking skills, and a passion for driving innovation and positive change in healthcare through AI technology.
Exemption Status
Exempt
Compensation Detail
$127,961.60 - $185,515.20 / year
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
Monday - Friday, 8am - 5pm This is a hybrid position and must be located within 100 miles of a Mayo Clinic campus for occasional on-site expectations based on business needs (about once a month).
Weekend Schedule
NA
International Assignment
No
Site Description
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Recruiter
Laura Percival
See All 17 AI Data Engineer Jobs in Minnesota
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Find AI Data Engineer JobsAI Data Engineer Jobs by City in Minnesota
Where Minnesota roles are concentrated, by current openings.
AI Data Engineer Job Market in Minnesota
A snapshot from current Minnesota openings, updated as new roles post.
Who's Hiring



What Minnesota Employers Look For
The qualifications that appear most often in AI data engineer jobs across Minnesota.
- Bachelor's or master's degree in computer science, data science, or a related engineering field
- Proficiency in Python and SQL with hands-on experience building and deploying ML pipelines
- Experience with cloud platforms such as AWS, Azure, or Google Cloud for data infrastructure
- Familiarity with large language models, generative AI frameworks, or MLOps tooling
- Ability to design and maintain scalable ETL and data pipeline architectures in production environments
- Strong communication skills for collaborating with cross-functional teams and translating data insights for stakeholders
AI Data Engineer Jobs in Minnesota: Frequently Asked Questions
How do you become a ai data engineer in Minnesota?
Most ai data engineers in Minnesota enter the field with a bachelor's degree in computer science, data science, mathematics, or a closely related discipline, though a master's degree strengthens candidacy for senior roles. There is no state-issued license required to work as an ai data engineer in Minnesota. Employers in the Twin Cities and Rochester typically prioritize demonstrated experience with machine learning tools, cloud platforms, and data pipeline development over any single credential, making portfolio projects and certifications from major cloud providers highly valued.
How much do AI data engineers make in Minnesota?
AI data engineers in Minnesota earn a median of about $128,800 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $65,730 for the lowest 10% to over $179,640 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire ai data engineers in Minnesota?
Companies currently hiring ai data engineers in Minnesota include Mayo Clinic, Optum, and Loram, per current listings on Migrate Mate as of September 2026. Minnesota's deep concentration of healthcare, retail, and financial services companies means ai data engineers here frequently work on applied ML problems in those industries.
Which Minnesota cities have the most ai data engineer jobs?
Minneapolis, Rochester, and Eden Prairie lead for ai data engineer openings in Minnesota. The Twin Cities metro drives the majority of postings, anchored by major corporate headquarters in retail, finance, and healthcare, while Rochester's concentration of medical technology and Mayo Clinic operations generates consistent demand, and Duluth contributes a smaller but growing share tied to regional healthcare and logistics employers.
Are there remote ai data engineer jobs in Minnesota?
Yes, and more than most fields. About 100% of ai data engineer openings tied to Minnesota are remote or hybrid as of September 2026, reflecting how naturally this work fits distributed teams. The most remote-friendly portions of the role tend to be pipeline development, model training, and data architecture work, while roles that require close collaboration with on-site business units more often carry a hybrid requirement.
How can I get hired as a ai data engineer in Minnesota with little or no experience?
The most realistic entry path is through a data analyst or data engineer role at a large Minnesota employer, then building toward AI-specific responsibilities. Companies like UnitedHealth Group and Target run new-grad and rotational data programs that place candidates without direct AI experience into teams where they can develop ML skills on the job. Building a portfolio of machine learning projects, earning a cloud provider certification, and applying to associate data engineer or junior ML engineer postings gives candidates without a full work history a concrete competitive edge.
Where can I find and apply to ai data engineer jobs in Minnesota?
You can find and apply to ai data engineer jobs in Minnesota on Migrate Mate, which lists current openings from employers across the state. Search the listings to find roles that match your experience and location preference, then apply directly to the ones that fit.
See All 17 AI Data Engineer Jobs in Minnesota
Find roles in Minnesota that match your experience and apply in just a few clicks.
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