AI Engineer Jobs in Missouri

AI Engineer jobs in Missouri are in active demand, with strong concentrations in financial services, healthcare technology, and defense contracting across Kansas City, St. Louis, and Columbia. Major employers with a lasting footprint hiring ai engineers in Missouri include Cerner (now Oracle Health), Edward Jones, and Boeing Defense. The most sought-after specialties in the state are machine learning infrastructure, natural language processing, and AI-driven analytics. Find a role that fits below and apply directly.

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Overview

Open roles23
Top employerMastercard
Top citySt. Louis, MO
Cities hiring9
Work type40% Hybrid
Top credentialBachelor's degree

Showing 5 of 23+ AI Engineer jobs

Lead AI Platform Engineer
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Added 5d ago
Lead AI Platform Engineer
Mastercard
O'Fallon, Missouri
IT Support
Project Management
Technical Program Management
$140k - $277k/yr
10,000+

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CHTR - B2 - Senior Kafka Engineer / Administrator - Agentic AI
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Added 1w ago
CHTR - B2 - Senior Kafka Engineer / Administrator - Agentic AI
Capgemini
St. Louis, Missouri
Software Engineering
Systems Administration
Technical Program Management
$32.36 - $50.56/hr
10,000+

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Senior Site Reliability Engineer – Cloud & AI Platforms
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Added 1w ago
Senior Site Reliability Engineer – Cloud & AI Platforms
Cognizant
Earth City, Missouri
Consulting & Professional Services
Software Engineering
Solutions Engineering & Architecture
Technical Program Management
Hybrid
10,000+

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Software Engineer - AI Trainer
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Added 1w ago
Software Engineer - AI Trainer
AfterQuery Experts
Columbia, Missouri
Customer Support
IT Support
IT Support & Systems Administration
Technical Program Management
$60 - $80/hr
Remote (US)
Bachelor's degree

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AI & Automation Engineer
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Added 2w ago
AI & Automation Engineer
Foley Equipment Company
Kansas City, Missouri
Business Operations
Customer Success
Project Management
On-Site
Bachelor's degree
501-1,000

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See All 23 AI Engineer Jobs in Missouri

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AI Engineer Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

St. Louis
8 jobs
O'Fallon
4 jobs
Kansas City
3 jobs
Springfield
2 jobs
Mexico
1 job
Monett
1 job
Columbia
1 job
Earth City
1 job
Cape Girardeau
1 job

AI Engineer Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

Mastercard4 open roles
Clayco2 open roles
Jack Henry & Associates2 open roles

What Missouri Employers Look For

The qualifications that appear most often in AI engineer jobs across Missouri.

  • Bachelor's or master's degree in computer science, data science, or a related field
  • Proficiency in Python and machine learning frameworks such as TensorFlow or PyTorch
  • Experience designing, training, and deploying production-grade machine learning models
  • Familiarity with cloud platforms including AWS, Azure, or Google Cloud for AI workloads
  • Strong understanding of data pipelines, feature engineering, and model evaluation techniques
  • Ability to communicate AI concepts and results clearly to non-technical stakeholders

AI Engineer Jobs in Missouri: Frequently Asked Questions

How do you become a ai engineer in Missouri?

AI engineering in Missouri has no state-issued license or registration requirement, so the path centers on education and demonstrated skills. Most Missouri employers expect at least a bachelor's degree in computer science, data science, or a closely related field, with a master's preferred for research-heavy roles. Building a portfolio of deployed projects and earning cloud or machine learning certifications from providers like AWS or Google strengthens a candidate's profile with Missouri employers considerably.

Which companies hire ai engineers in Missouri?

Employers hiring ai engineers in Missouri right now include Mastercard, Clayco, and Jack Henry & Associates, based on current listings on Migrate Mate as of November 2026. Missouri's concentration of financial services firms in St. Louis and healthcare technology companies in Kansas City means those two sectors consistently account for a large share of the state's ai engineer openings.

Which Missouri cities have the most ai engineer jobs?

St. Louis, O'Fallon, and Kansas City have the most ai engineer openings in Missouri. Kansas City and St. Louis drive the bulk of demand through their large financial services, healthcare, and defense employer bases, while Columbia benefits from the University of Missouri's research ecosystem and the technology firms that cluster around it.

Are there remote ai engineer jobs in Missouri?

Yes, and more than most fields. About 70% of ai engineer openings tied to Missouri are remote or hybrid as of November 2026, reflecting the desk-based, software-driven nature of the work. Roles focused on model development, data pipeline engineering, and research tend to be the most remote-friendly, while positions requiring close collaboration with hardware teams or embedded systems are more likely to require on-site presence.

How can I get hired as a ai engineer in Missouri with little or no experience?

The most realistic entry path is through a data analyst or software engineering role at a Missouri employer that uses machine learning internally, then transitioning into AI work as you build relevant skills. Large Missouri employers in healthcare technology and financial services often run new-graduate rotational programs where early-career hires contribute to AI projects alongside experienced engineers. Building a public portfolio of machine learning projects and earning a recognized cloud or AI certification gives candidates a concrete edge when applying to those programs.

Where can I find and apply to ai engineer jobs in Missouri?

You can find and apply to ai engineer jobs in Missouri on Migrate Mate, which lists current Missouri openings across industries and experience levels. Find roles that fit your background and apply directly without needing to create a profile or sign up first.

See All 23 AI Engineer Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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