Application Engineer Jobs in San Francisco, CA

Application Engineer jobs in San Francisco are concentrated in SoMa, the Financial District, and Mission Bay, driven by enterprise software, cloud infrastructure, and life sciences employers. Companies currently hiring include Abridge, ALTRUIST, and BRAIN. Find a role that fits below and apply directly.

Find Application Engineer Jobs

Overview

Open roles266+
Top employerAbridge
Work type64% Hybrid
Top credentialBachelor of Science
Companies hiring19

Showing 5 of 266+ Application Engineer jobs

Ouster
Director, Global Field Application Engineer
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Ouster
Added 4d ago
Director, Global Field Application Engineer
Ouster
San Francisco, California
Solutions Architecture
Solutions Engineering & Architecture
Technical Program Management
$190k - $240k/yr
Bachelor's degree in mechanical engineering

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Cvent
Application Support Engineer I (Must be based in Pacific Time Zone)
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Cvent
Added 5d ago
Application Support Engineer I (Must be based in Pacific Time Zone)
Cvent
San Francisco, California
AI (Artificial Intelligence)
Data Science
$79k - $90k/yr
Remote (US)
Bachelor of Science
1,001-5,000

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ALTRUIST
Senior Application Security Engineer (Blue Team)
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ALTRUIST
Added 2w ago
Senior Application Security Engineer (Blue Team)
ALTRUIST
San Francisco, California
Engineering (Non-Software)
Mechanical Engineering
Product Management
$200k - $240k/yr
Hybrid
Bachelor of Science
11-50

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ALTRUIST
Senior Application Security Engineer (Red Team)
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ALTRUIST
Added 2w ago
Senior Application Security Engineer (Red Team)
ALTRUIST
San Francisco, California
Account Management
Business Development
Customer Success
Sales
$200k - $240k/yr
Hybrid
Bachelor of Science
11-50

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Brainlab
Biomedical Engineer (Application Consultant)
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Brainlab
Added 1mo ago
Biomedical Engineer (Application Consultant)
Brainlab
San Francisco, California
Account Management
Business Development
Sales
$70k - $85k/yr
Bachelor of Science
1,001-5,000

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See All 266+ Application Engineer Jobs in San Francisco

Find roles in San Francisco that match your experience and apply in just a few clicks.

Find Application Engineer Jobs

Application Engineer Job Market in San Francisco

Who's Hiring

  • Abridge
    Abridge25
  • ALTRUIST
    ALTRUIST25
  • BRAIN
    BRAIN13
  • Cvent
    Cvent13
  • MERCOR
    MERCOR13

Top Industries Hiring

  • Technology & Software63
  • Science & Research25
  • Energy13
  • Insurance13
  • Manufacturing13

Application Engineer Jobs in San Francisco: Frequently Asked Questions

How do I get a application engineer job in San Francisco?

Target the enterprise software, cloud, and biotech companies concentrated in SoMa, Mission Bay, and the Financial District, where demand for application engineers is highest. Hands-on experience with APIs, systems integration, or customer-facing technical implementations gives you a clear edge. Candidates who can demonstrate pre-sales or post-sales technical support experience tend to move quickly through hiring pipelines at San Francisco's fast-moving tech and life sciences firms.

Which companies hire application engineers in San Francisco?

San Francisco application engineer roles are posted by Abridge, ALTRUIST, and BRAIN and others right now, based on current listings on Migrate Mate as of September 2026. The city draws a mix of large enterprise software vendors, early-stage startups, and medical device or biotech firms, all of which rely on application engineers to bridge technical products and customer needs.

Are there remote application engineer jobs in San Francisco?

Yes, though availability depends heavily on the role: customer-facing and integration-heavy positions typically require on-site or hybrid presence, while more analytical or documentation-focused work can run fully remote. About 86% of application engineer openings tied to San Francisco are remote or hybrid as of September 2026. Product support and pre-sales engineering roles at San Francisco software companies represent the largest share of those flexible arrangements.

How can I get a application engineer job in San Francisco with little or no experience?

The most realistic entry path in San Francisco is through junior technical support or solutions engineer roles at mid-stage SaaS companies in SoMa or the Financial District, where structured onboarding is more common. Bootcamp graduates and candidates with strong API or scripting fundamentals are regularly considered for associate-level positions. Targeting companies that sell complex software to enterprise clients gives you the best chance, since those teams need people who can learn a product deeply and explain it clearly.

Which industries hire the most application engineers in San Francisco?

The sectors hiring the most application engineers in San Francisco are Technology & Software, Science & Research, and Energy, based on current listings on Migrate Mate as of September 2026. San Francisco's dense concentration of enterprise software headquarters, cloud infrastructure companies, and life sciences campuses in Mission Bay creates sustained, year-round demand for technical roles that sit between product and customer.

See All 266+ Application Engineer Jobs in San Francisco

Find roles in San Francisco that match your experience and apply in just a few clicks.

Find Application Engineer Jobs