Senior Level Chief Operating Officer Jobs

Senior level chief operating officer jobs place experienced leaders at the center of enterprise-wide execution, where they own operational strategy, direct cross-functional teams, and are accountable for outcomes at scale. Openings concentrate in Biotechnology & Pharmaceuticals, Healthcare & Medical Services, and Technology & Software, with a mix of on-site, hybrid, and remote roles available, and employers like CVS Health, Revolution Medicines, and Cornerstone Caregiving hiring at this level now.

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Overview

Open roles261+
Top stateCalifornia
Top employerCVS Health
Top citySan Francisco, CA
Work type74% On-site
Top industryBiotechnology

Showing 5 of 261+ Senior Level Chief Operating Officer jobs

CVS Health
Lead Director - Security Operations Center (SOC)
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CVS Health
New 19h ago
Lead Director - Security Operations Center (SOC)
CVS Health
Montpelier, Vermont
Cybersecurity
Compliance & Legal
Security Engineering
Compliance & Risk
$144k - $288k/yr
On-Site
Bachelor's
10,000+

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CVS Health
Lead Director - Security Operations Center (SOC)
We won't show you this job again
CVS Health
New 19h ago
Lead Director - Security Operations Center (SOC)
CVS Health
Harrisburg, Pennsylvania
Cybersecurity
Compliance & Legal
Security Engineering
Compliance & Risk
$144k - $288k/yr
On-Site
Bachelor's
10,000+

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CVS Health
Lead Director - Security Operations Center (SOC)
We won't show you this job again
CVS Health
New 22h ago
Lead Director - Security Operations Center (SOC)
CVS Health
Augusta, Maine
Business Analysis
Data Analytics
Data Science
$144k - $288k/yr
Bachelor's degree in information technology
10,000+

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CVS Health
Lead Director - Security Operations Center (SOC)
We won't show you this job again
CVS Health
New 19h ago
Lead Director - Security Operations Center (SOC)
CVS Health
Topeka, Kansas
Cybersecurity
Compliance & Legal
Security Engineering
Compliance & Risk
$144k - $288k/yr
On-Site
Bachelor's
10,000+

Have you applied for this role?

CVS Health
Lead Director - Security Operations Center (SOC)
We won't show you this job again
CVS Health
New 22h ago
Lead Director - Security Operations Center (SOC)
CVS Health
Cheyenne, Wyoming
Account Management
Customer Service
Customer Support
$144k - $288k/yr
Bachelor's degree in information technology
10,000+

Have you applied for this role?

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Senior Level Chief Operating Officer Job Market

Who's Hiring

  • CVS Health
    CVS Health20
  • Revolution Medicines
    Revolution Medicines13
  • Cornerstone Caregiving
    Cornerstone Caregiving8
  • Jobot
    Jobot6
  • Watson Institute
    Watson Institute5

Top Industries Hiring

  • Biotechnology & Pharmaceuticals37
  • Healthcare & Medical Services29
  • Technology & Software25
  • Insurance23
  • Consulting & Professional Services18

Senior Level Chief Operating Officer Jobs: Frequently Asked Questions

How do I get a senior level chief operating officer job?

Employers at this level look for candidates who have led large-scale operational change, owned P&L or enterprise-wide outcomes, and built or restructured teams. A strong edge comes from demonstrating cross-functional authority, not just functional expertise. Executives who can show measurable results from initiatives they personally drove, and who bring board-level communication experience, move to the top of candidate lists.

Which companies hire senior level chief operating officers?

Companies hiring senior level chief operating officers right now include CVS Health, Revolution Medicines, and Cornerstone Caregiving, based on current listings on Migrate Mate as of September 2026. Hiring at this level comes from a mix of enterprise corporations, high-growth companies scaling their operations, and organizations navigating significant transformation or expansion.

Are there remote senior level chief operating officer jobs?

Yes, though on-site and hybrid arrangements are common at this leadership tier. About 26% of senior level chief operating officer openings are remote or hybrid as of September 2026, reflecting that many organizations require executive presence for culture-setting and cross-functional alignment while still offering flexibility in how that presence is structured.

What makes a chief operating officer role senior level?

Senior level chief operating officer roles are defined by enterprise-wide scope, direct accountability for operational performance, and authority over multiple functions or business units. These positions typically involve setting operational strategy rather than executing within it, mentoring other leaders, and serving as a key decision-maker alongside the CEO. The distinction from mid-level roles is ownership of outcomes, not just oversight of processes.

Which industries hire the most senior level chief operating officers?

Senior Level chief operating officer roles concentrate in Biotechnology & Pharmaceuticals, Healthcare & Medical Services, and Technology & Software, based on current listings on Migrate Mate as of September 2026. These sectors tend to drive demand at this level because they operate at significant scale, face ongoing operational complexity, and require experienced executives who can align people, process, and technology across large organizations.