Senior Level Clinical Informatics Manager Jobs

Senior level clinical informatics manager jobs place experienced professionals in charge of clinical systems strategy, cross-functional implementation programs, and the informatics teams that deliver measurable outcomes. Roles concentrate across Healthcare & Medical Services and Biotechnology & Pharmaceuticals, with a mix of on-site, hybrid, and remote positions, and employers like Sutter Health, Community Health Systems, and Revolution Medicines hiring at this level now.

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Overview

Open roles6
Top stateCalifornia
Top employerSutter Health
Top citySacramento, CA
Work type100% On-site
Top industryHealthcare

Showing 5 of 6+ Senior Level Clinical Informatics Manager jobs

Director Clinical Informatics
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Added 1mo ago
Director Clinical Informatics
University of Maryland Medical System
Columbia, Maryland
Clinical Support
Healthcare Administration
Project Management
$66 - $106/hr
Master's degree in business
10,000+

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Medical Director, Clinical Informatics
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Added 4mo ago
Medical Director, Clinical Informatics
Sutter Health
Sacramento, California
Healthcare Administration
Clinical Support
Medical Specialists
$520k/yr
On-Site
Doctorate

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Medical Director, Clinical Informatics, Behavioral Health
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Added 4mo ago
Medical Director, Clinical Informatics, Behavioral Health
Sutter Health
Sacramento, California
Healthcare Administration
Clinical Support
Medical Specialists
$208k/yr
On-Site
Doctorate

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Senior Director, Clinical Informatics
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Added 4mo ago
Senior Director, Clinical Informatics
Community Health Systems
United States
Healthcare Administration
Clinical Support
Human Resources
Project & Program Management
Project Management
On-Site
Bachelor's

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Executive Director, Translational and Clinical Informatics
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Added 8mo ago
Executive Director, Translational and Clinical Informatics
Revolution Medicines, Inc.
Redwood City, California
Project & Program Management
Data Science & Analytics
Cloud & DevOps
Software Engineering
Strategy & Corporate Development
Project Management
Data Science
Business Strategy
$265k - $331k/yr
On-Site
Associate's

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Senior Level Clinical Informatics Manager Job Market

Who's Hiring

Sutter Health2 open roles
Community Health Systems2 open roles
Revolution Medicines1 open role

Top Industries Hiring

  • Healthcare & Medical Services
  • Biotechnology & Pharmaceuticals

Senior Level Clinical Informatics Manager Jobs: Frequently Asked Questions

How do I get a senior level clinical informatics manager job?

Employers at this level expect candidates who have led enterprise-wide EHR implementations, governed clinical data standards, or directed informatics programs across multiple service lines. Demonstrating ownership of outcomes, not just participation in projects, sets strong candidates apart. Experience mentoring analysts, presenting to clinical leadership, and driving measurable quality or efficiency improvements is what moves a resume to the top of the shortlist.

Which companies hire senior level clinical informatics managers?

Companies hiring senior level clinical informatics managers right now include Sutter Health, Community Health Systems, and Revolution Medicines, based on current listings on Migrate Mate as of November 2026. Hiring at this level comes from large health systems, academic medical centers, payer organizations, and health IT vendors building out clinical leadership teams.

Are there remote senior level clinical informatics manager jobs?

Yes, though availability varies by employer and role scope. About 0% of senior level clinical informatics manager openings are remote or hybrid as of November 2026, reflecting the field's shift toward distributed clinical informatics leadership. Fully remote roles tend to favor candidates with strong experience managing remote teams and working across time zones with clinical stakeholders.

What makes a clinical informatics manager role senior level?

Senior level roles are defined by program ownership, strategic scope, and leadership responsibility. Where mid-level managers coordinate workflows and support implementations, senior professionals set the informatics roadmap, govern clinical data integrity standards, and mentor junior staff. They operate as decision-makers with accountability to executive and clinical leadership, often managing multiple initiatives and vendor relationships simultaneously.

Which industries hire the most senior level clinical informatics managers?

Senior Level clinical informatics manager roles concentrate in Healthcare & Medical Services and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of November 2026. These sectors drive demand because they operate large clinical environments where data governance, interoperability, and evidence-based workflow design directly affect patient outcomes and regulatory compliance.