Senior Level Clinical Informatics Nurse Jobs

Senior level clinical informatics nurse jobs place experienced nurses in charge of system design decisions, clinical workflow optimization, and the cross-functional teams that implement and sustain health information technology at scale. Roles are concentrated across Healthcare & Medical Services and Biotechnology & Pharmaceuticals, with a mix of on-site, remote, and hybrid settings, and employers like Sutter Health, Community Health Systems, and Revolution Medicines hiring at this level now.

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Overview

Open roles6
Top stateCalifornia
Top employerSutter Health
Top citySacramento, CA
Work type100% On-site
Top industryHealthcare

Showing 5 of 6+ Senior Level Clinical Informatics Nurse jobs

Director Clinical Informatics
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Added 1mo ago
Director Clinical Informatics
University of Maryland Medical System
Columbia, Maryland
Clinical Support
Healthcare Administration
Project Management
$66 - $106/hr
Master's degree in business
10,000+

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Medical Director, Clinical Informatics
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Added 4mo ago
Medical Director, Clinical Informatics
Sutter Health
Sacramento, California
Healthcare Administration
Clinical Support
Medical Specialists
$520k/yr
On-Site
Doctorate

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Medical Director, Clinical Informatics, Behavioral Health
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Added 4mo ago
Medical Director, Clinical Informatics, Behavioral Health
Sutter Health
Sacramento, California
Healthcare Administration
Clinical Support
Medical Specialists
$208k/yr
On-Site
Doctorate

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Senior Director, Clinical Informatics
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Added 4mo ago
Senior Director, Clinical Informatics
Community Health Systems
United States
Healthcare Administration
Clinical Support
Human Resources
Project & Program Management
Project Management
On-Site
Bachelor's

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Executive Director, Translational and Clinical Informatics
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Added 8mo ago
Executive Director, Translational and Clinical Informatics
Revolution Medicines, Inc.
Redwood City, California
Project & Program Management
Data Science & Analytics
Cloud & DevOps
Software Engineering
Strategy & Corporate Development
Project Management
Data Science
Business Strategy
$265k - $331k/yr
On-Site
Associate's

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See All 6 Senior Level Clinical Informatics Nurse Jobs

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Senior Level Clinical Informatics Nurse Job Market

Who's Hiring

Sutter Health2 open roles
Community Health Systems2 open roles
Revolution Medicines1 open role

Top Industries Hiring

  • Healthcare & Medical Services
  • Biotechnology & Pharmaceuticals

Senior Level Clinical Informatics Nurse Jobs: Frequently Asked Questions

How do I get a senior level clinical informatics nurse job?

Employers at this level expect candidates who have led EHR implementations, chaired clinical governance committees, or owned system optimization initiatives end to end. Demonstrated ability to translate clinical needs into technical requirements, mentor junior informaticists, and collaborate with IT and administration will set you apart. Certifications like CPHIMS or CNIO credentials strengthen your profile considerably at this stage.

Which companies hire senior level clinical informatics nurses?

Companies hiring senior level clinical informatics nurses right now include Sutter Health, Community Health Systems, and Revolution Medicines, based on current listings on Migrate Mate as of November 2026. Hiring at this level comes primarily from large health systems, academic medical centers, and health technology vendors that need experienced clinical informaticists to lead enterprise-wide initiatives.

Are there remote senior level clinical informatics nurse jobs?

Yes, remote and hybrid availability is meaningful at this level. About 0% of senior level clinical informatics nurse openings are remote or hybrid as of November 2026, reflecting how health systems and vendors increasingly distribute their informatics leadership across multiple sites. On-site roles tend to cluster around large health system headquarters or major implementation projects.

What makes a clinical informatics nurse role senior level?

Senior level roles are defined by ownership and scope rather than task execution. You are expected to set direction for clinical informatics programs, lead multidisciplinary teams through system implementations, and serve as the expert resource others escalate to. Mentoring mid-level staff, contributing to strategic planning, and accountability for outcomes across an entire service line or institution are hallmarks of this tier.

Which industries hire the most senior level clinical informatics nurses?

Senior level clinical informatics nurse roles concentrate in Healthcare & Medical Services and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring at this level because large patient volumes, complex regulatory requirements, and ongoing EHR optimization create sustained demand for experienced clinical informatics leadership.