Clinical Nurse Jobs in Chicago, IL
Clinical Nurse jobs in Chicago are in strong demand, with openings concentrated in the Medical District, Streeterville, and Hyde Park across major health systems, academic medical centers, and specialty clinics. Employers actively hiring right now include Northwestern Medicine, Rush University Medical Center, and Cook County Health & Hospitals System. See the openings below and apply to the ones that match your experience.
Find Clinical Nurse JobsOverview
Showing 5 of 157+ Clinical Nurse jobs









Hourly Pay Range:
$50.64 - $78.49 - The hourly pay rate offered is determined by a candidate's expertise and years of experience, among other factors.Position Highlights:
- Position : Clinical Nurse Manager - ICU + IMCU
- Location: Chicago, IL
- Full time/Part time : Full Time, 40 hours/week
- Hours : Day shift (Monday-Friday), but flexibility required as hours can vary based on department needs. Management responsibilities will include weekend/nights and holidays as needed.
- Required Travel: No
What you will do:
- Provide clinical leadership and guidance to nursing staff, ensuring adherence to established clinical protocols, safety standards, and quality of care. Monitor patient care activities to maintain quality and safety.
- Supervise and mentor nursing staff, including RNs, LPNs, and CNAs. Coordinate staff schedules, assignments, and performance evaluations. Foster a positive and collaborative work environment.
- Ensure the delivery of compassionate, patient-centered care. Address patient and family concerns and inquiries promptly and professionally. Collaborate with the healthcare team to develop and implement care plans.
- Lead quality improvement initiatives, audits, and compliance efforts. Identify areas for improvement and implement corrective actions to enhance patient outcomes.
- Efficiently manage unit resources, including staffing, supplies, and equipment. Assist in budget planning and control expenses within the unit.
- Facilitate ongoing education and training for nursing staff to enhance their clinical skills and knowledge. Keep abreast of the latest developments in healthcare.
- Oversee accurate and complete documentation of patient assessments, care plans, and interventions in electronic health records.
- Ensure compliance with all state and federal regulations, as well as hospital policies and procedures. Maintain a safe and sanitary patient care environment. Collaborate with other departments, including physicians, case managers, and ancillary services, to coordinate patient care and optimize the patient experience.
What you will need:
- Bachelors Degree Nursing Required; Masters Degree Nursing Preferred Or Masters Degree Health Administration Preferred
- 5+ Years of clinical nursing experience, with at least 3 years in a supervisory or leadership role.
- Current Registered Nurse (RN) licensure in the state of Illinois
- Basic Life Support (BLS) - American Heart Association (AHA) BLS certification NIHSS Certification
Benefits
- Premium pay for eligible employees
- Career Pathways to Promote Professional Growth and Development
- Various Medical, Dental, Pet and Vision options
- Tuition Reimbursement
- Discounted Parking at Designated Locations
- Wellness Program Savings Plan
- Health Savings Account Options
- Retirement Options with Company Match
- Paid Time Off and Holiday Pay
- Community Involvement Opportunities
Endeavor Health is a fully integrated healthcare delivery system committed to providing access to quality, vibrant, community-connected care, serving an area of more than 4.2 million residents across six northeast Illinois counties. Our more than 25,000 team members and more than 6,000 physicians aim to deliver transformative patient experiences and expert care close to home across more than 300 ambulatory locations and eight acute care hospitals – Edward (Naperville), Elmhurst, Evanston, Glenbrook (Glenview), Highland Park, Northwest Community (Arlington Heights) Skokie and Swedish (Chicago) – all recognized as Magnet hospitals for nursing excellence. For more information, visit www.endeavorhealth.org .
When you work for Endeavor Health, you will be part of an organization that encourages its employees to achieve career goals and maximize their professional potential.
Please explore our website ( www.endeavorhealth.org ) to better understand how Endeavor Health delivers on its mission to “help everyone in our communities be their best”.
Endeavor Health is committed to working with and providing reasonable accommodation to individuals with disabilities. Please refer to the main career page for more information.
At Endeavor Health, we are united by a shared commitment to working together to create a culture of connection and belonging—each of us bringing different skills and experiences as we deliver safe, seamless, and personal care. Every person, every time. We are committed to fostering an environment where all team members can be their best, learn, and pursue excellence together.
EOE: Race/Color/Sex/Sexual Orientation/ Gender Identity/Religion/National Origin/Disability/Vets, VEVRRA Federal Contractor.
See All 157+ Clinical Nurse Jobs in Chicago
Find roles in Chicago that match your experience and apply in just a few clicks.
Find Clinical Nurse JobsClinical Nurse Job Market in Chicago
Who's Hiring
- Northwestern Medicine37

- Rush University Medical Center23

- Cook County Health & Hospitals System20

- Endeavor Health14

- UChicago Medicine11

Top Industries Hiring
- Education
- Healthcare & Medical Services
- Transportation & Logistics
Clinical Nurse Jobs in Chicago: Frequently Asked Questions
How do I get a clinical nurse job in Chicago?
Your strongest path into Chicago's market is targeting its large academic medical centers, Level I trauma centers, and specialty hospitals, which hire across nearly every clinical specialty. The Medical District on the Near West Side and Streeterville's hospital corridor concentrate the densest openings. Candidates with ICU, ED, or oncology experience move quickly here. Networking through unit-specific nurse residency cohorts at major Chicago health systems and attending local American Nurses Association Illinois chapter events also sharpens your edge.
Which companies hire clinical nurses in Chicago?
Employers hiring clinical nurses in Chicago right now include Northwestern Medicine, Rush University Medical Center, and Cook County Health & Hospitals System, based on current listings on Migrate Mate as of October 2026. Chicago's market is anchored by large integrated health systems, world-class academic medical centers affiliated with major universities, community hospital networks serving the city's diverse neighborhoods, and growing outpatient and specialty clinic groups.
Are there remote clinical nurse jobs in Chicago?
Yes, though remote work is limited for clinical nurses since most roles require direct patient care in a facility. About 0% of clinical nurse openings tied to Chicago are remote or hybrid as of October 2026, covering roles where it applies. In Chicago, the remote-friendly subset tends to include telephonic triage, utilization review, case management, and care coordination positions with health plans and managed care organizations headquartered in the city.
How can I get a clinical nurse job in Chicago with little or no experience?
The most realistic entry path in Chicago is applying to nurse residency programs at the city's large academic medical centers and community hospital networks, which are specifically structured for new graduates. Chicago's Federally Qualified Health Centers and safety-net hospitals in neighborhoods like Pilsen and Englewood also hire entry-level nurses and often offer mentorship. Completing clinical rotations at Chicago-area facilities during nursing school and expressing willingness to work nights or weekends strengthens your application considerably.
Which industries hire the most clinical nurses in Chicago?
The sectors hiring the most clinical nurses in Chicago are Education, Healthcare & Medical Services, and Transportation & Logistics, based on current listings on Migrate Mate as of October 2026. Chicago's concentration of nationally ranked academic medical centers, a large public health system, and a growing network of outpatient specialty and ambulatory surgery centers makes it one of the Midwest's highest-volume hiring markets for clinical nursing talent.
See All 157+ Clinical Nurse Jobs in Chicago
Find roles in Chicago that match your experience and apply in just a few clicks.
Find Clinical Nurse Jobs