Clinical Nurse Jobs in Chicago, IL

Clinical Nurse jobs in Chicago are in strong demand, with openings concentrated in the Medical District, Streeterville, and Hyde Park across major health systems, academic medical centers, and specialty clinics. Employers actively hiring right now include Northwestern Medicine, Rush University Medical Center, and UChicago Medicine. See the openings below and apply to the ones that match your experience.

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Overview

Open roles150+
Top employerNorthwestern Medicine
Work type86% On-site
Top credentialBLS Certification
Companies hiring17

Showing 5 of 150+ Clinical Nurse jobs

Northwestern Medicine
Clinical Research Nurse Coordinator
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Northwestern Medicine
New 13h ago
Clinical Research Nurse Coordinator
Northwestern Medicine
Chicago, Illinois
Biotech & Life Sciences
Clinical Trials
Healthcare Administration
Research & Academia
$43 - $68.8/hr
CPR Certification
10,000+

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University of Illinois
UI Health - Clinical Nurse Consultant II (Transplant)
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University of Illinois
Added 1d ago
UI Health - Clinical Nurse Consultant II (Transplant)
University of Illinois
Chicago, Illinois
Clinical Trials
Healthcare Administration
Nursing
Patient Services & Wellbeing
$41 - $95/hr
CPR Certification
10,000+

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Northwestern Medicine
Clinical Nurse- NICU Full Time Nights
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Northwestern Medicine
Added 1d ago
Clinical Nurse- NICU Full Time Nights
Northwestern Medicine
Chicago, Illinois
Business Operations
Business Strategy
Consulting & Professional Services
$36.5 - $58.4/hr
BLS Certification
10,000+

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Humboldt Park Health
Clinical Nurse Educator FT
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Humboldt Park Health
Added 1d ago
Clinical Nurse Educator FT
Humboldt Park Health
Chicago, Illinois
Business Development
Growth Marketing
Marketing
TNCC Certification
501-1,000

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Northwestern Medicine
Clinical Nurse, Inpatient Psychiatry Full-Time Rotating Shifts (day/evening)
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Northwestern Medicine
Added 1d ago
Clinical Nurse, Inpatient Psychiatry Full-Time Rotating Shifts (day/evening)
Northwestern Medicine
Chicago, Illinois
Business Operations
Business Strategy
Consulting & Professional Services
$36.5 - $58.4/hr
BLS Certification
10,000+

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See All 150+ Clinical Nurse Jobs in Chicago

Find roles in Chicago that match your experience and apply in just a few clicks.

Find Clinical Nurse Jobs

Clinical Nurse Job Market in Chicago

Who's Hiring

  • Northwestern Medicine
    Northwestern Medicine59
  • Rush University Medical Center
    Rush University Medical Center18
  • UChicago Medicine
    UChicago Medicine10
  • SAINT MARY OF NAZARETH HOSPITAL
    SAINT MARY OF NAZARETH HOSPITAL10
  • University of Illinois
    University of Illinois8

Top Industries Hiring

  • Healthcare & Medical Services18
  • Education10
  • Transportation & Logistics3

Clinical Nurse Jobs in Chicago: Frequently Asked Questions

How do I get a clinical nurse job in Chicago?

Your strongest path into Chicago's market is targeting its large academic medical centers, Level I trauma centers, and specialty hospitals, which hire across nearly every clinical specialty. The Medical District on the Near West Side and Streeterville's hospital corridor concentrate the densest openings. Candidates with ICU, ED, or oncology experience move quickly here. Networking through unit-specific nurse residency cohorts at major Chicago health systems and attending local American Nurses Association Illinois chapter events also sharpens your edge.

Which companies hire clinical nurses in Chicago?

Employers hiring clinical nurses in Chicago right now include Northwestern Medicine, Rush University Medical Center, and UChicago Medicine, based on current listings on Migrate Mate as of August 2026. Chicago's market is anchored by large integrated health systems, world-class academic medical centers affiliated with major universities, community hospital networks serving the city's diverse neighborhoods, and growing outpatient and specialty clinic groups.

Are there remote clinical nurse jobs in Chicago?

Yes, though remote work is limited for clinical nurses since most roles require direct patient care in a facility. About 14% of clinical nurse openings tied to Chicago are remote or hybrid as of August 2026, covering roles where it applies. In Chicago, the remote-friendly subset tends to include telephonic triage, utilization review, case management, and care coordination positions with health plans and managed care organizations headquartered in the city.

How can I get a clinical nurse job in Chicago with little or no experience?

The most realistic entry path in Chicago is applying to nurse residency programs at the city's large academic medical centers and community hospital networks, which are specifically structured for new graduates. Chicago's Federally Qualified Health Centers and safety-net hospitals in neighborhoods like Pilsen and Englewood also hire entry-level nurses and often offer mentorship. Completing clinical rotations at Chicago-area facilities during nursing school and expressing willingness to work nights or weekends strengthens your application considerably.

Which industries hire the most clinical nurses in Chicago?

The sectors hiring the most clinical nurses in Chicago are Healthcare & Medical Services, Education, and Transportation & Logistics, based on current listings on Migrate Mate as of August 2026. Chicago's concentration of nationally ranked academic medical centers, a large public health system, and a growing network of outpatient specialty and ambulatory surgery centers makes it one of the Midwest's highest-volume hiring markets for clinical nursing talent.

See All 150+ Clinical Nurse Jobs in Chicago

Find roles in Chicago that match your experience and apply in just a few clicks.

Find Clinical Nurse Jobs