Nurse Practitioner Jobs in Illinois
Nurse Practitioner jobs in Illinois are among the most active in the Midwest, with strong demand across hospital systems, primary care networks, and specialty outpatient clinics at every level from new graduate to lead NP. Chicago, Naperville, and Springfield anchor most of the hiring, with major systems like Northwestern Medicine, Advocate Health Care, and OSF HealthCare consistently posting openings. Family practice, acute care, and psychiatric mental health are the most in-demand specialties across the state. Find a role that fits below and apply directly.
Find Nurse Practitioner JobsOverview
Showing 4 of 135+ Nurse Practitioner jobs
- Providing high-quality patient care and a truly personalized, patient-centric experience aligned with each patient’s preferences, goals, and needs
- Primarily inpatient neurosurgery care, including comprehensive neurological assessments, daily rounding, histories and physicals, new consults, admissions, and discharges
- Develop and implement individualized treatment plans in collaboration with attending neurosurgeons
- Prepare patients for surgery, manage postoperative care, and support smooth care transitions across the continuum
- Order and interpret diagnostic tests, including laboratory work and imaging, prescribe medications, and document all care provided
- Provide patient and family education to enhance understanding of diagnoses, treatment options, and long-term management plans
- Perform procedures alongside residents
- Exposure to a broad range of acute and complex neurological cases
- Collaborative work environment with neurosurgeons, residents, advanced practice providers, and multidisciplinary teams
- Three 12-hour shifts per week (5:45 AM – 6:15 PM), Rotating weekends and holidays as part of the schedule
OSF HealthCare offers a comprehensive Compensation and Total Rewards Package which includes:
-
Generous paid time off!
- Vacation and holiday time off to get away and recharge
- Well-being time for self-care, mission trips, or whatever makes you happy!
- Sick leave for you or to care for an ill family member
- Continuing Medical Education (CME) time and dollars
- Concierge relocation services
- Health, life, dental, and retirement plans
- Paid occurrence-based malpractice
- Student Loan repayment counseling
- Career development opportunities
-
Full-time, clinical base hourly pay range for this position: $60.39-$68.10. This position is salaried.
- Range shown should be used as an estimate and can be impacted by many factors including but not limited to the critical need of the position, overall experience and qualifications, community need, and other considerations. Additional compensation components may be applicable such as bonuses or incentives which may or may not be based on metric achievement
THE COMMUNITY
Peoria, Illinois
- OSF HealthCare Saint Francis Medical Center has fulfilled the Mission of our Sisters since 1877. OSF Saint Francis has grown into the fifth-largest medical center in Illinois, with nearly 6,000 employees and 640+ patient beds. A major teaching affiliate of the University of Illinois College of Medicine Peoria, OSF Saint Francis is the area’s only Level I Trauma Center and tertiary care medical center. We are also home to OSF HealthCare Children’s Hospital of Illinois, OSF HealthCare Cancer Institute and the OSF HealthCare Illinois Neurological Institute.
- Nestled in the heart of the Illinois River Valley, Peoria is the largest Illinois metropolitan area outside of Chicago and St. Louis. Here, you can live as big or small as your heart desires! Check out the City of Peoria, with its urban amenities and hustle. Or choose a suburb, small town or rural life, with a laid-back vibe and community schools.
- Regarded as an ideal blend of urban, suburban and rural influences, the Greater Peoria area offers a lower cost of living, easy commutes and amenities that appeal to an array of lifestyles.
- In Peoria, you’ll find an educated populace fueled by respected universities and medical schools, professional and NCAA Division I college sports, and of course the home base for the OSF HealthCare Ministry which was founded here in 1877.
- Visit osfcareers.org/peoria to download our full community guide.
REQUIRED QUALIFICATIONS
- Licensed to provide either advanced practice nursing services in the State of Illinois as issued by the Illinois Department of Financial and Professional Regulation in accordance with the Illinois Nurse Practice Act OR physician assistant services as issued by the Illinois Department of Financial and Professional Regulation in accordance with the Illinois Physician Assistant Practice Act of 1987.
- Licensed by the Federal Drug Enforcement Administration and the State of Illinois to prescribe narcotics, if applicable.
- BLS/ACLS Certified.
- Neurosurgery experience preferred, new graduates will be considered
- Excellent clinical judgment, communication, and teamwork skills
- Ability to thrive in a fast-paced, hospital environment while maintaining patient-centered focus.
- Must be eligible as a provider for Medicare, Medicaid, and other federal health programs.
- Provider shall meet all qualifications to participate in OSF's programs for professional malpractice and other liability coverage.
PREFERRED QUALIFICATIONS
Demonstrates the knowledge and skills necessary to provide patient care aligned to the preferences, goals, and needs of the patients served.
OSF HealthCare is an Equal Opportunity Employer.
- Providing high-quality patient care and a truly personalized, patient-centric experience aligned with each patient’s preferences, goals, and needs
- Primarily inpatient neurosurgery care, including comprehensive neurological assessments, daily rounding, histories and physicals, new consults, admissions, and discharges
- Develop and implement individualized treatment plans in collaboration with attending neurosurgeons
- Prepare patients for surgery, manage postoperative care, and support smooth care transitions across the continuum
- Order and interpret diagnostic tests, including laboratory work and imaging, prescribe medications, and document all care provided
- Provide patient and family education to enhance understanding of diagnoses, treatment options, and long-term management plans
- Perform procedures alongside residents
- Exposure to a broad range of acute and complex neurological cases
- Collaborative work environment with neurosurgeons, residents, advanced practice providers, and multidisciplinary teams
- Three 12-hour shifts per week (5:45 AM – 6:15 PM), Rotating weekends and holidays as part of the schedule
OSF HealthCare offers a comprehensive Compensation and Total Rewards Package which includes:
-
Generous paid time off!
- Vacation and holiday time off to get away and recharge
- Well-being time for self-care, mission trips, or whatever makes you happy!
- Sick leave for you or to care for an ill family member
- Continuing Medical Education (CME) time and dollars
- Concierge relocation services
- Health, life, dental, and retirement plans
- Paid occurrence-based malpractice
- Student Loan repayment counseling
- Career development opportunities
-
Full-time, clinical base hourly pay range for this position: $60.39-$68.10. This position is salaried.
- Range shown should be used as an estimate and can be impacted by many factors including but not limited to the critical need of the position, overall experience and qualifications, community need, and other considerations. Additional compensation components may be applicable such as bonuses or incentives which may or may not be based on metric achievement
THE COMMUNITY
Peoria, Illinois
- OSF HealthCare Saint Francis Medical Center has fulfilled the Mission of our Sisters since 1877. OSF Saint Francis has grown into the fifth-largest medical center in Illinois, with nearly 6,000 employees and 640+ patient beds. A major teaching affiliate of the University of Illinois College of Medicine Peoria, OSF Saint Francis is the area’s only Level I Trauma Center and tertiary care medical center. We are also home to OSF HealthCare Children’s Hospital of Illinois, OSF HealthCare Cancer Institute and the OSF HealthCare Illinois Neurological Institute.
- Nestled in the heart of the Illinois River Valley, Peoria is the largest Illinois metropolitan area outside of Chicago and St. Louis. Here, you can live as big or small as your heart desires! Check out the City of Peoria, with its urban amenities and hustle. Or choose a suburb, small town or rural life, with a laid-back vibe and community schools.
- Regarded as an ideal blend of urban, suburban and rural influences, the Greater Peoria area offers a lower cost of living, easy commutes and amenities that appeal to an array of lifestyles.
- In Peoria, you’ll find an educated populace fueled by respected universities and medical schools, professional and NCAA Division I college sports, and of course the home base for the OSF HealthCare Ministry which was founded here in 1877.
- Visit osfcareers.org/peoria to download our full community guide.
REQUIRED QUALIFICATIONS
- Licensed to provide either advanced practice nursing services in the State of Illinois as issued by the Illinois Department of Financial and Professional Regulation in accordance with the Illinois Nurse Practice Act OR physician assistant services as issued by the Illinois Department of Financial and Professional Regulation in accordance with the Illinois Physician Assistant Practice Act of 1987.
- Licensed by the Federal Drug Enforcement Administration and the State of Illinois to prescribe narcotics, if applicable.
- BLS/ACLS Certified.
- Neurosurgery experience preferred, new graduates will be considered
- Excellent clinical judgment, communication, and teamwork skills
- Ability to thrive in a fast-paced, hospital environment while maintaining patient-centered focus.
- Must be eligible as a provider for Medicare, Medicaid, and other federal health programs.
- Provider shall meet all qualifications to participate in OSF's programs for professional malpractice and other liability coverage.
PREFERRED QUALIFICATIONS
Demonstrates the knowledge and skills necessary to provide patient care aligned to the preferences, goals, and needs of the patients served.
OSF HealthCare is an Equal Opportunity Employer.
See All 135+ Nurse Practitioner Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
Find Nurse Practitioner JobsNurse Practitioner Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Nurse Practitioner Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
Who's Hiring
- Trio Health Partners17
- Northwestern Medicine10
- WellNow Urgent Care7
- Advocate Aurora Health5
- Alteas Health3
Top Industries Hiring
- Healthcare & Medical Services
- Education
What Illinois Employers Look For
The qualifications that appear most often in nurse practitioner jobs across Illinois.
- Active Illinois Advanced Practice Registered Nurse license required
- Current national board certification such as ANCC or AANP required
- Master of Science in Nursing or Doctor of Nursing Practice degree required
- Current and unrestricted Illinois Controlled Substance license for prescribing roles
- Current BLS and ACLS certification required at time of hire
- One or more years of clinical experience in a relevant specialty preferred
Nurse Practitioner Jobs in Illinois: Frequently Asked Questions
How do you become a nurse practitioner in Illinois?
To become a nurse practitioner in Illinois, you must earn a Master of Science in Nursing or Doctor of Nursing Practice from an accredited program, pass a national board certification exam through the ANCC or AANP, and apply for an Advanced Practice Registered Nurse license through the Illinois Department of Financial and Professional Regulation. Roles requiring prescriptive authority also require a separate Illinois Controlled Substance license.
How much do nurse practitioners make in Illinois?
Nurse practitioners in Illinois earn a median of about $130,680 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $102,440 for the lowest 10% to over $161,470 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire nurse practitioners in Illinois?
Employers hiring nurse practitioners in Illinois right now include Trio Health Partners, Northwestern Medicine, and WellNow Urgent Care, based on current listings on Migrate Mate as of August 2026. Illinois's dense network of large integrated health systems and federally qualified health centers means consistent openings across both urban and rural settings statewide.
Which Illinois cities have the most nurse practitioner jobs?
Chicago, Illinois, and Rockford have the most nurse practitioner openings in Illinois. Chicago dominates due to its concentration of major academic medical centers and multi-specialty outpatient groups, while Naperville and Springfield benefit from large regional hospital systems and growing suburban primary care networks that create steady demand outside the city core.
Are there remote nurse practitioner jobs in Illinois?
Yes, but they're rare. About 26% of nurse practitioner openings tied to Illinois are remote or hybrid as of August 2026, reflecting how hands-on the clinical role typically is. The remote openings that do exist tend to be in telehealth urgent care, chronic disease management, or utilization review positions that don't require in-person patient contact.
How can I get hired as a nurse practitioner in Illinois with little or no experience?
The most realistic entry path is a new-graduate NP residency or fellowship, and large Illinois systems like Northwestern Medicine, Advocate Health Care, and UChicago Medicine run structured programs designed for NPs without post-certification experience. Candidates who transition from an experienced RN background in a related specialty, such as critical care or emergency nursing, are consistently prioritized. Holding an active Illinois APRN license and a current national board certification before applying gives you a meaningful edge over candidates still in process.
Where can I find and apply to nurse practitioner jobs in Illinois?
You can find and apply to nurse practitioner jobs in Illinois on Migrate Mate, which lists current openings from employers hiring across the state. Search the listings, find roles that fit your specialty and experience level, and apply directly to the ones that match.
See All 135+ Nurse Practitioner Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
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