Nurse Practitioner Jobs in Chicago, IL
Nurse Practitioner jobs in Chicago are concentrated in the Medical District, Hyde Park, and Streeterville, with strong demand across hospital systems, community health centers, and specialty clinics. Employers hiring right now include Northwestern Medicine, Aayu Clinics, and Ascension. Scan the live roles below and apply to whichever ones fit.
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At Northwestern Medicine, every patient interaction makes a difference in cultivating a positive workplace. This patient-first approach is what sets us apart as a leader in the healthcare industry. As an integral part of our team, you'll have the opportunity to join our quest for better health care, no matter where you work within the Northwestern Medicine system. We pride ourselves on providing competitive benefits: from tuition reimbursement and loan forgiveness to 401(k) matching and lifecycle benefits, our goal is to take care of our employees. Ready to join our quest for better?
Job Description
Northwestern Medicine has an exciting opportunity for either an Acute Care Nurse Practitioner or a Physician Assistant to work in our inpatient General Cardiology and Advanced Heart Failure department. Galter 10 is a service of 17 APPs covering 48 beds. The APP will support 4 Cardiology services, with rotating attendings each week. APPs can expect an average load of 7 patients a day. The APP will provide primary service to patients experience complex, advanced Heart Failure care, VADs, and General Cardiology.
Schedule: 4x10 hour shifts with rotating weekends and holidays
- no nights or on-call
Essential Functions:
- Demonstrates clinical expertise and expanded knowledge through patient care activities which may include diagnosis and management of a wide range of health problems.
- Responsible for health outcome of an assigned patient population.
- Confers with collaborating physician and other health professionals in area of clinical expertise.
- Develops appropriate educational systems for patients, families and staff in areas of expertise.
- Mentors graduate students in aspects of advanced practice and patient care.
- Actively participates in quality improvement and/or research pertinent to area of expertise.
Responsibilities:
- Conducts comprehensive appraisals of patients' health status by taking health histories and performing physical examinations in clinical area.
- Provides direct clinical care to patients.
- Prescribes/orders medications, therapies; orders/interprets laboratory tests, x-rays and procedures according to clinical privileges.
- Evaluates patients to determine their need for further health care.
- Provides comprehensive teaching to patients and families.
- Documents in the medical record all care and education provided and/or procedures performed for which the Licensed Advanced Practice Provider is responsible.
- Refers to other disciplines as appropriate.
- Consultant to other disciplines in areas of expertise.
- Integrates research based knowledge and clinical expertise in decision making.
- Exemplifies a professional image in appearance, manner and presentation.
- Advocate for patients, families, coworkers, and the community.
- Maintains certifications and continuing education as required for licensure and privileging.
- Serves as a patient advocate and role model for "Patients First".
- Participates in unit/departmental/divisional or hospital committees/task forces as appropriate.
- Provides comprehensive teaching strategies for patients and their families.
- Develops and participates in programs to meet continuing education needs of staff.
- Serves as a role model and preceptor to students.
- Provides formal education to both internal and external groups pertinent to area of specialty.
- Participates in quality improvement and/or research initiatives for specific patient population as appropriate.
Qualifications
Required:
- Master’s degree from an accredited school/college of nursing OR master's degree from an accredited Physician Assistant Program
- Acute care certification required for APRNs
- Current license as a Registered Nurse in the State of Illinois. Current license as an Advanced Practice Registered Nurse in the State of Illinois. Certification as an Advanced Practice Registered Nurse by a national certifying body as approved by the Illinois Department of Regulation APRN Board. Once licensed may apply for a controlled substance license and DEA number OR Master’s degree from an accredited Physician Assistant Program/Current license as a Physician Assistant in the State of Illinois. Once licensed may apply for a controlled substance license and DEA number
- Privileged and credentialed through the Medical Staff Office (MSO)
- Basic Life Support for Healthcare Providers (American Heart Association) certification
- Advanced Cardiovascular Life Support (ACLS) certification required as specified by department
Preferred:
- 2 years of clinical experience
Additional Information
Northwestern Medicine is an equal opportunity employer (disability, VETS) and does not discriminate in hiring or employment on the basis of age, sex, race, color, religion, national origin, gender identity, veteran status, disability, sexual orientation or any other protected status.
Background Check
Northwestern Medicine conducts a background check that includes criminal history on newly hired team members and, at times, internal transfers. If you are offered a position with us, you will be required to complete an authorization and disclosure form that gives Northwestern Medicine permission to run the background check. Results are evaluated on a case-by-case basis, and we follow all local, state, and federal laws, including the Illinois Health Care Worker Background Check Act.
Artificial Intelligence Disclosure
Artificial Intelligence (AI) tools may be used in some portions of the candidate review process for this position, however, all employment decisions will be made by a person.
Benefits
We offer a wide range of benefits that provide employees with tools and resources to improve their physical, emotional, and financial well-being while providing protection for unexpected life events.
Click on or copy and paste URL to your browser to view detailed benefits information https://jobs.nm.org/benefits
Please refer to the Benefits Eligibility by Employment Classification to determine benefits eligibility for job postings.
If sign-on bonus is included in a job posting eligibility is as followed: Internal employees and rehires who left Northwestern Medicine within 1 year are not eligible for the sign-on bonus. Exception: New graduate internal employees seeking their first licensed clinical position as a Registered Nurse at NM may be eligible.
See All 156+ Nurse Practitioner Jobs in Chicago
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Who's Hiring
- Northwestern Medicine75

- Aayu Clinics12
- Ascension6

- Sinai Chicago6

- Lake County, IL6

Nurse Practitioner Jobs in Chicago: Frequently Asked Questions
How do I get a nurse practitioner job in Chicago?
Focus your search on Chicago's three strongest hiring corridors: the Illinois Medical District on the Near West Side, the academic medical centers in Hyde Park, and the specialty clinic clusters in Streeterville and the Gold Coast. Health systems, federally qualified health centers, and multispecialty groups all hire steadily. Candidates with primary care, acute care, or psychiatric mental health certification tend to move fastest in this market. Tailoring your application to the patient population a specific clinic or system serves gives you a real edge.
Which companies hire nurse practitioners in Chicago?
Employers hiring nurse practitioners in Chicago right now include Northwestern Medicine, Aayu Clinics, and Ascension, based on current listings on Migrate Mate as of October 2026. Chicago's hiring landscape is anchored by large academic medical centers, sprawling hospital networks, and an active network of community health organizations serving diverse neighborhoods citywide.
Are there remote nurse practitioner jobs in Chicago?
Yes, though opportunities are limited given how hands-on the role is by nature. About 19% of nurse practitioner openings tied to Chicago are remote or hybrid as of October 2026, and those positions skew heavily toward telehealth primary care, behavioral health, and care management roles rather than procedural or acute care settings. Chicago-based telehealth platforms and insurance-adjacent care coordination programs represent the most consistent source of fully remote openings.
How can I get a nurse practitioner job in Chicago with little or no experience?
The most realistic entry path in Chicago is a new graduate residency or fellowship program, several of which are offered through the city's major academic medical centers and federally qualified health centers. Community health organizations serving Chicago's South and West Side neighborhoods are particularly active in hiring new graduates. Acute care experience as an RN before your NP graduation strengthens your candidacy considerably, and applying to high-volume primary care or urgent care clinics broadens your options when hospital residency slots are limited.
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