Nurse Practitioner Jobs in Massachusetts
Nurse Practitioner jobs in Massachusetts are among the most active in the country, with strong demand concentrated in primary care, psychiatry, and acute care settings tied to the state's dense hospital and academic medical center infrastructure. Boston, Worcester, and Springfield are the primary hiring hubs, anchored by large systems like Mass General Brigham, Beth Israel Lahey Health, and UMass Memorial Health, which consistently post openings at every level from new-graduate NP through senior and leadership roles. Psychiatric and mental health nurse practitioner positions have seen particularly sustained demand statewide. Find a role that fits below and apply directly.
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Overview
Join our care team as a Nurse Practitioner and deliver thoughtful, evidence-informed care across patient settings. You’ll assess health needs, develop treatment plans, prescribe medications within applicable regulations, and coordinate care with healthcare professionals. Your impact: Clear assessments and coordinated follow-up help patients and families understand care options and move toward appropriate treatment.
Duties
- Conduct comprehensive medical assessments and physical examinations for patients admitted for detoxification from alcohol, opioids, benzodiazepines, and other substances.
- Obtain medical, psychiatric, substance use, surgical, and medication histories, including allergies and prior withdrawal complications.
- Assess and monitor withdrawal symptoms using standardized tools such as CIWA-Ar for alcohol withdrawal and COWS for opioid withdrawal, as appropriate.
- Develop, implement, and manage individualized detoxification and withdrawal management treatment plans.
- Prescribe, administer, and adjust medications for withdrawal management in accordance with clinical protocols, applicable regulations, and scope of practice.
- Evaluate patients for medical stability and identify complications, including seizures, delirium tremens, dehydration, electrolyte imbalances, and other acute medical conditions.
- Order, review, and interpret laboratory tests, toxicology screens, diagnostic studies, and other medically indicated evaluations.
- Perform daily medical rounds and reassess patients' clinical status, response to treatment, and medication effectiveness.
- Manage co-occurring medical conditions, including hypertension, diabetes, infections, gastrointestinal concerns, and other chronic or acute illnesses.
- Initiate and manage medications for opioid use disorder, including buprenorphine or other appropriate treatments, within applicable prescribing requirements and facility protocols.
- Monitor for medication side effects, drug interactions, oversedation, respiratory depression, and other adverse reactions.
- Determine the need for higher levels of medical care and arrange emergency transfers or hospital referrals when clinically indicated.
- Collaborate with nursing staff, behavioral health clinicians, therapists, case managers, and other members of the interdisciplinary treatment team.
- Provide patient education regarding withdrawal symptoms, medication adherence, overdose prevention, relapse prevention, and ongoing recovery treatment.
- Coordinate discharge planning, medication reconciliation, referrals, and continuity of care with outpatient providers and substance use treatment programs.
- Maintain accurate, timely, and confidential medical records, including assessments, progress notes, orders, and discharge summaries.
- Ensure compliance with facility policies, infection prevention practices, documentation standards, and applicable state and federal regulations.
- Participate in treatment planning, quality improvement initiatives, clinical reviews, and staff education as appropriate.
Experience
- Required: Nurse Practitioner credentials and authorization to practice as an advanced practice provider, as applicable to the role and jurisdiction; strong patient assessment, clinical documentation, anatomy, physiology, and medical terminology skills.
- Relevant experience may include primary care, hospital medicine, emergency medicine, critical or intensive care, pediatrics, geriatrics, behavioral health, gastroenterology, dialysis, hospice and palliative medicine, occupational health, or post-acute care.
- Additional useful experience includes triage, acute pain management, suturing, phlebotomy, venipuncture, catheter care, tube feeding, airway management, and working with children or older adults.
- Familiarity with Kipu , Microsoft Outlook
- Other setting-specific experience may include assisted living, nursing homes, home care, memory care, trauma centers, operating rooms, intensive care units, or outpatient care.
Pay: $80.00 - $100.00 per hour
Expected hours: 1.0 – 16.0 per week
Benefits:
- Flexible schedule
Work Location: In person
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Find Nurse Practitioner JobsNurse Practitioner Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Nurse Practitioner Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
- Education
- Insurance
What Massachusetts Employers Look For
The qualifications that appear most often in nurse practitioner jobs across Massachusetts.
- Active Massachusetts nurse practitioner license issued by the Board of Registration in Nursing
- National board certification as NP from ANCC or AANPCB in relevant specialty
- Master of Science in Nursing or Doctor of Nursing Practice from accredited program
- Current DEA registration and prescriptive authority under Massachusetts collaborative agreement requirements
- Minimum of one to two years of clinical NP experience in primary or specialty care
- Current BLS and ACLS certification required for acute care and hospital-based settings
Nurse Practitioner Jobs in Massachusetts: Frequently Asked Questions
How do you become a nurse practitioner in Massachusetts?
To practice as a nurse practitioner in Massachusetts, you must hold an active license issued by the Massachusetts Board of Registration in Nursing, which requires completing an accredited graduate-level NP program at the master's or doctoral level and passing a national certification exam through ANCC or AANPCB in your chosen specialty. Massachusetts also requires NPs to maintain a collaborative practice agreement with a supervising physician for prescriptive authority, including DEA registration for controlled substances.
How much do nurse practitioners make in Massachusetts?
Nurse practitioners in Massachusetts earn a median of about $142,440 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $111,950 for the lowest 10% to over $207,710 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire nurse practitioners in Massachusetts?
Employers hiring nurse practitioners in Massachusetts right now include ConvenientMD, Beth Israel Lahey Health, and Massachusetts General Hospital, based on current listings on Migrate Mate as of October 2026. Massachusetts's concentration of large academic medical systems and community health centers means openings appear across a wide range of care settings, from flagship hospital campuses to federally qualified health centers serving underserved communities statewide.
Which Massachusetts cities have the most nurse practitioner jobs?
Boston, Needham, and Lowell have the most nurse practitioner openings in Massachusetts. Boston dominates because of its dense cluster of academic medical centers and specialty hospitals, while Worcester and Springfield draw hiring volume from regional health systems like UMass Memorial and Baystate Health that serve large catchment areas well outside those city limits.
Are there remote nurse practitioner jobs in Massachusetts?
Yes, but they're rare. About 22% of nurse practitioner openings tied to Massachusetts are remote or hybrid as of October 2026, reflecting that most NP work requires in-person patient care. The roles most likely to allow remote components are telepsychiatry and chronic disease management positions, where follow-up consultations can be conducted via telehealth platforms under Massachusetts telehealth practice standards.
How can I get hired as a nurse practitioner in Massachusetts with little or no experience?
The most realistic entry path is applying directly to new-graduate NP residency or fellowship programs offered by Massachusetts health systems, including structured programs at Mass General Brigham and Beth Israel Lahey Health that are specifically designed for NPs transitioning from RN practice. Candidates with strong RN backgrounds in ICU, emergency, or psychiatric settings have a meaningful edge because that clinical depth transfers directly. Completing your Massachusetts collaborative practice agreement requirements and securing ANCC or AANPCB board certification before your first application removes a major hiring barrier at most Massachusetts employers.
Where can I find and apply to nurse practitioner jobs in Massachusetts?
You can find and apply to nurse practitioner jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings across hospitals, community health centers, specialty practices, and telehealth employers. Find roles that fit your specialty and experience level and apply directly.
See All 112+ Nurse Practitioner Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
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