Clinical Nurse Jobs in Illinois

Clinical Nurse jobs in Illinois are concentrated in hospital systems, outpatient clinics, and long-term care facilities, with Chicago functioning as one of the most active markets in the Midwest. Most openings are in Chicago, Springfield, and Rockford, where large employers like Northwestern Medicine, Rush University Medical Center, and Advocate Health have deep, lasting clinical nurse workforces. Demand is strongest in medical-surgical, critical care, and emergency nursing, with consistent openings at every level from new graduate to senior clinical nurse. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles150+
Top employerNorthwestern Medicine
Top cityChicago, IL
Cities hiring44
Work type75% On-site
Top industryHealthcare

Showing 5 of 150+ Clinical Nurse jobs

Northwestern Medicine
Clinical Research Nurse Coordinator
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Northwestern Medicine
New 13h ago
Clinical Research Nurse Coordinator
Northwestern Medicine
Chicago, Illinois
Biotech & Life Sciences
Clinical Trials
Healthcare Administration
Research & Academia
$43 - $68.8/hr
CPR Certification
10,000+

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Northwestern Medicine
Clinical Practice Specialist Registered Nurse Educator ICU Full-time Days
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Northwestern Medicine
New 13h ago
Clinical Practice Specialist Registered Nurse Educator ICU Full-time Days
Northwestern Medicine
DeKalb, Illinois
Business Operations
Project Management
Quality Assurance & Testing (QA Testing)
$40.5 - $64.8/hr
Bachelor of Science
10,000+

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Northwestern Medicine
Clinical Practice Specialist Nurse Educator Medical Surgical, Float and IMCU Part-time Nights
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Northwestern Medicine
New 13h ago
Clinical Practice Specialist Nurse Educator Medical Surgical, Float and IMCU Part-time Nights
Northwestern Medicine
DeKalb, Illinois
Business Operations
Project Management
Quality Assurance & Testing (QA Testing)
$40.5 - $64.8/hr
Bachelor of Science
10,000+

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Saint Francis Hospital
Clinical Nurse Supervisor - Wound Care
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Saint Francis Hospital
Added 1d ago
Clinical Nurse Supervisor - Wound Care
Saint Francis Hospital
Evanston, Illinois
Clinical Support
Healthcare Administration
Human Resources
$36.75 - $55.7/hr
Managed Registered Nurses (RNs)

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University of Illinois
UI Health - Clinical Nurse Consultant II (Transplant)
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University of Illinois
Added 1d ago
UI Health - Clinical Nurse Consultant II (Transplant)
University of Illinois
Chicago, Illinois
Clinical Trials
Healthcare Administration
Nursing
Patient Services & Wellbeing
$41 - $95/hr
CPR Certification
10,000+

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See All 150+ Clinical Nurse Jobs in Illinois

Find roles in Illinois that match your experience and apply in just a few clicks.

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Clinical Nurse Jobs by City in Illinois

Where Illinois roles are concentrated, by current openings.

Belleville
14 jobs
Shiloh
10 jobs
Evanston
6 jobs
Oak Lawn
4 jobs
Alton
3 jobs
Geneva
3 jobs
Elmhurst
3 jobs
Glenview
3 jobs

Clinical Nurse Job Market in Illinois

A snapshot from current Illinois openings, updated as new roles post.

Who's Hiring

  • Northwestern Medicine
    Northwestern Medicine30
  • BJC HealthCare
    BJC HealthCare26
  • Endeavor Health
    Endeavor Health15
  • Advocate Aurora Health
    Advocate Aurora Health13
  • Rush University Medical Center
    Rush University Medical Center7

Top Industries Hiring

  • Healthcare & Medical Services20
  • Education5
  • Transportation & Logistics1

What Illinois Employers Look For

The qualifications that appear most often in clinical nurse jobs across Illinois.

  • Active Registered Nurse license issued or recognized by the Illinois Department of Financial and Professional Regulation
  • Associate or Bachelor of Science in Nursing degree from an accredited program
  • Current BLS certification required before the first patient care shift
  • One or more years of direct patient care experience in a clinical setting
  • Demonstrated proficiency with electronic health record systems such as Epic or Cerner
  • Strong communication skills and ability to collaborate within interdisciplinary care teams

Clinical Nurse Jobs in Illinois: Frequently Asked Questions

How do you become a clinical nurse in Illinois?

To become a clinical nurse in Illinois, you must graduate from an accredited nursing program, pass the NCLEX-RN, and obtain licensure through the Illinois Department of Financial and Professional Regulation. The IDFPR issues and renews registered nurse licenses in Illinois. Most clinical nurse roles require at least an Associate Degree in Nursing, though many Illinois hospital systems prefer or require a Bachelor of Science in Nursing for direct patient care positions.

How much do clinical nurses make in Illinois?

Clinical nurses in Illinois earn a median of about $95,990 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $69,170 for the lowest 10% to over $118,190 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire clinical nurses in Illinois?

Employers hiring clinical nurses in Illinois right now include Northwestern Medicine, BJC HealthCare, and Endeavor Health, based on current listings on Migrate Mate as of August 2026. Illinois's large integrated health systems and academic medical centers drive the bulk of consistent clinical nurse hiring across the state.

Which Illinois cities have the most clinical nurse jobs?

Chicago, Belleville, and Shiloh have the most clinical nurse openings in Illinois. Chicago dominates due to its concentration of major academic medical centers and large hospital systems, while Springfield's state government hospitals and Rockford's regional health systems generate steady demand that draws clinical nurses beyond the Chicago metro.

Are there remote clinical nurse jobs in Illinois?

Yes, but they're rare. About 25% of clinical nurse openings tied to Illinois are remote or hybrid as of August 2026, reflecting the hands-on, bedside nature of most clinical nurse work. The portions of the role most likely to allow remote work are utilization review, case management, and telephone triage nursing, where direct patient contact is not required.

How can I get hired as a clinical nurse in Illinois with little or no experience?

The most realistic entry path is a new graduate residency program, which large Illinois employers like Northwestern Medicine and Advocate Health run specifically to bring nurses without hospital experience into structured clinical environments. Applying to med-surg or general inpatient units is the most accessible starting point, and candidates transitioning from adjacent roles such as medical assistant, patient care technician, or licensed practical nurse often move in with a clear advantage. Completing ACLS certification before applying strengthens an entry-level application at most Illinois hospital systems.

Where can I find and apply to clinical nurse jobs in Illinois?

You can find and apply to clinical nurse jobs in Illinois on Migrate Mate, which lists current Illinois openings in one place. Search the roles available, find the ones that match your credentials and preferred location, and apply directly to the listings that fit your background.

See All 150+ Clinical Nurse Jobs in Illinois

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