Clinical Nurse Jobs in Boston, MA
Clinical Nurse jobs in Boston are concentrated in the Longwood Medical Area, Downtown, and the South End, with demand driven by academic medical centers, community health networks, and specialty hospitals. Employers hiring right now include CareSource, Headlands Research, and Tufts Medical Center. Scan the live roles below and apply to whichever ones fit.
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Overview
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Primary Duties and Responsibilities:
- Assists principal investigator with protocol development.
- Assists principal investigator as appropriate with the Institute’s protocol review process.
- Assists the principal investigator in developing the protocol budget.
- Collaborates with the Dana-Farber Harvard Cancer Center DFHCC quality assurance of clinical trials office in developing protocol specific materials.
- Serves as research coordinator for National Cancer Institute, pharmaceutical-sponsored, and National Cooperative Group protocols.
Research:
- Assists with recruitment and registration of patients to clinical trials.
- Coordinates scheduling of patient’s laboratory and radiographic assessments, admissions and clinic visits.
- Monitors test results as appropriate.
- Coordinates protocol data management as necessary.
- Collaborates with staff within the Institute and with outside organizations in the completion of
Clinical:
- Coordinates study enrollment, protocol treatment, and completion of study requirements for patients participating in clinical trials.
- Works collaboratively and functions as an effective member of the health care team.
- Collaborates with Care Coordination for all patient care referrals.
- Collaborates with primary nurse in assuring that patient care needs are met.
- Provides protocol education to patients and families; adapts interactions based on age-specific needs of the patient.
- Collects and prepares required specimens for analysis and monitors test results, as appropriate.
- Documents in charts as appropriate and communicates observations and findings to protocol investigator and attending physicians.
- Provides protocol in-service training and serves as a resource to the health care team.
- Monitors the environment of care with attention to patient safety, and assures compliance with regulatory agency standards.
- Maintains clinical practice that is evidence-based and consistent with nursing policies, procedures, licensure/registration requirements, and professional scope and standards.
- Participates in QA/QI projects for the clinical program and the Division of Nursing and Patient Care Services.
- Adheres to the Code of Ethics for Nurses with Interpretive Statements (ANA, 2001) in all aspects of professional practice.
- Fosters an environment that is sensitive to the needs of diverse populations, including but not limited to culture, ethnicity, gender, and age.
- Administers medications as necessary.
- Maintains BLS certification.
Professional Development:
- Identifies areas for professional growth.
- Formulates professional goals, objectives and methods for accomplishing these.
- Pursues active membership of local and national professional organizations.
- Supports research activities within the Division of Nursing and Patient Care Services.
- Participates in Division of Nursing / Institute committees.
- Meets all annual evaluation requirements and competencies within the established time period.
- Collaborates in preparing professional reports, articles, and presentations for colleagues and the public.
Minimum Job Qualifications:
Education: Associate Degree, Nursing. Baccalaureate Degree in Nursing strongly preferred. If Associate Degree in Nursing, must complete BSN degree within 4 years. Experience: Completion of the Oncology Nurse Residency Program (ONRP) or 1 year of recent experience as a Registered Nurse. Ambulatory and/or oncology experience preferred.
License/Certification/Registration Required:
Licensed as a Registered Nurse in the Commonwealth of Massachusetts, or State of New Hampshire as appropriate required. AHA BLS required (AHA ACLS accepted as minimum requirement). Professional nursing certification preferred (OCN, BMTCN, CPHON, AOCNP, CRNI, RN-BC).
Supervisory Responsibilities:
None
Patient Contact:
Yes.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to .
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
EEO Poster
.Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$42.65 - $105.81See All 84 Clinical Nurse Jobs in Boston
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Find Clinical Nurse JobsClinical Nurse Job Market in Boston
Who's Hiring
- CareSource36

- Headlands Research6

- Tufts Medical Center6

- Beth Israel Lahey Health6

- Dana-Farber Cancer Institute6

Top Industries Hiring
- Healthcare & Medical Services21
- Biotechnology & Pharmaceuticals6
- Education3
- Government & Public Sector3
Clinical Nurse Jobs in Boston: Frequently Asked Questions
How do I get a clinical nurse job in Boston?
Focus your search on the Longwood Medical Area, which anchors Boston's healthcare economy with academic medical centers, cancer institutes, and specialty hospitals all within a concentrated corridor. Community health centers in Roxbury, Dorchester, and Jamaica Plain also hire consistently. Candidates with critical care, oncology, or pediatric experience stand out in this market. Tailoring your application to Boston's research-heavy institutions gives you a real edge.
Which companies hire clinical nurses in Boston?
Employers hiring clinical nurses in Boston right now include CareSource, Headlands Research, and Tufts Medical Center, based on current listings on Migrate Mate as of August 2026. Boston's hiring mix ranges from large academic medical systems and nationally ranked specialty hospitals to neighborhood-based community health centers and long-term care facilities.
Are there remote clinical nurse jobs in Boston?
Yes, though remote opportunities are limited for clinical nurses given the hands-on, patient-facing nature of most roles. About 15% of clinical nurse openings tied to Boston are remote or hybrid as of August 2026, with those positions typically covering utilization review, care coordination, and telehealth triage rather than bedside or procedural work.
How can I get a clinical nurse job in Boston with little or no experience?
The most realistic entry path in Boston is a new graduate residency program, offered by several of the city's large academic medical centers specifically to bridge from graduation to independent practice. Community health centers in neighborhoods like Roxbury and Dorchester also hire new nurses for primary care and preventive health roles. Completing clinical rotations at Boston-area facilities and obtaining BLS and ACLS certification before applying strengthens any entry-level application considerably.
Which industries hire the most clinical nurses in Boston?
Boston clinical nurse roles concentrate in Healthcare & Medical Services, Biotechnology & Pharmaceuticals, and Education, based on current listings on Migrate Mate as of August 2026. Boston's unusually dense cluster of teaching hospitals, research institutions, and specialty care networks means clinical nurse demand here is driven heavily by complex, high-acuity patient populations that require specialized nursing expertise.
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