Clinical Nurse Jobs in St. Louis, MO

Clinical Nurse jobs in St. Louis are in strong demand, concentrated in the Central West End medical corridor, Midtown, and the hospital campuses anchoring Downtown and South St. Louis, across acute care, long-term care, and ambulatory settings. Employers hiring right now include BJC HealthCare, Washington University in St. Louis, and SSM Health. Scan the live roles below and apply to whichever ones fit.

Find Clinical Nurse Jobs

Overview

Open roles220+
Top employerBJC HealthCare
Work type44% Hybrid
Top credentialNursing Diploma
Companies hiring9

Showing 5 of 220+ Clinical Nurse jobs

NURSE, CLINICAL - PPCU FT Days
We won't show you this job again
Added 3d ago
NURSE, CLINICAL - PPCU FT Days
BJC HealthCare
St. Louis, Missouri
Clinical Support
Healthcare Administration
Human Resources
$32 - $48.28/hr
Nursing Diploma
10,000+

Have you applied for this role?

Clinical Nurse PACU Interventional Radiology
We won't show you this job again
Added 3d ago
Clinical Nurse PACU Interventional Radiology
BJC HealthCare
St. Louis, Missouri
Healthcare Administration
Human Resources
Nursing
Patient Services & Wellbeing
$32 - $48.28/hr
Nursing Diploma
10,000+

Have you applied for this role?

Wound Care - Clinical Nurse
We won't show you this job again
Added 3d ago
Wound Care - Clinical Nurse
BJC HealthCare
St. Louis, Missouri
Healthcare Administration
Human Resources
Nursing
Patient Services & Wellbeing
$32 - $48.28/hr
Nursing Diploma
10,000+

Have you applied for this role?

Clinical Nurse Gen Med Unit
We won't show you this job again
Added 3d ago
Clinical Nurse Gen Med Unit
BJC HealthCare
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
$32 - $48.28/hr
Nursing Diploma
10,000+

Have you applied for this role?

Clinical Nurse Post-surgical Ortho Unit
We won't show you this job again
Added 3d ago
Clinical Nurse Post-surgical Ortho Unit
BJC HealthCare
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
$32 - $48.28/hr
Nursing Diploma
10,000+

Have you applied for this role?

See All 220+ Clinical Nurse Jobs in St. Louis

Find roles in St. Louis that match your experience and apply in just a few clicks.

Find Clinical Nurse Jobs

Clinical Nurse Job Market in St. Louis

Who's Hiring

  • BJC HealthCare166
  • Washington University in St. Louis29
  • SSM Health12
  • Mercy5
  • IQVIA2

Top Industries Hiring

  • Healthcare & Medical Services

Clinical Nurse Jobs in St. Louis: Frequently Asked Questions

How do I get a clinical nurse job in St. Louis?

The strongest hiring in St. Louis clusters around the health systems anchoring the Central West End, the VA campus in Midtown, and the network of community hospitals and outpatient clinics in South City and the inner suburbs. Candidates with experience in med-surg, ICU, or oncology move fastest here. Tailoring your application to the specific unit and patient population a facility serves gives you a clear edge over generic submissions.

Which companies hire clinical nurses in St. Louis?

St. Louis clinical nurse roles are posted by BJC HealthCare, Washington University in St. Louis, and SSM Health and others right now, based on current listings on Migrate Mate as of November 2026. St. Louis draws from a mix of large academic medical centers, regional hospital networks, and a growing number of multispecialty outpatient groups that hire nurses across multiple care settings.

Are there remote clinical nurse jobs in St. Louis?

Yes, though remote work is limited for clinical nurses given the hands-on nature of direct patient care. About 83% of clinical nurse openings tied to St. Louis are remote or hybrid as of November 2026, concentrated in utilization review, case management, and telehealth triage roles. Those functions are the most realistic targets if you want flexibility without leaving nursing entirely.

How can I get a clinical nurse job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is a new-graduate residency program at one of the larger health systems in the Central West End or at a community hospital in the surrounding metro. These structured programs pair new nurses with mentors and rotate them through high-volume units. Acute care, long-term care facilities, and rehabilitation centers in the inner suburbs also hire new graduates more readily than specialty units and are a strong starting point for building clinical hours.

Which industries hire the most clinical nurses in St. Louis?

The sectors hiring the most clinical nurses in St. Louis are Healthcare & Medical Services, based on current listings on Migrate Mate as of November 2026. St. Louis has a dense concentration of academic medical centers, specialty hospitals, and a well-established network of outpatient and home health providers that collectively sustain consistent nursing demand across the metro.

See All 220+ Clinical Nurse Jobs in St. Louis

Find roles in St. Louis that match your experience and apply in just a few clicks.

Find Clinical Nurse Jobs