Clinical Nurse Jobs in St. Louis, MO
Clinical Nurse jobs in St. Louis are in strong demand, concentrated in the Central West End medical corridor, Midtown, and the hospital campuses anchoring Downtown and South St. Louis, across acute care, long-term care, and ambulatory settings. Employers hiring right now include BJC HealthCare, Washington University in St. Louis, and SSM Health. Scan the live roles below and apply to whichever ones fit.
Find Clinical Nurse JobsOverview
Showing 5 of 220+ Clinical Nurse jobs











- Saint Louis, Missouri
- Nursing Services
- Days
- Full-Time
- 116658
- $32.00 – $48.28 / hour (Salary or hourly rate is based on job qualifications and relevant work experience)
Job Description
- $15,000 Sign On Bonus Eligible (External Hires)
- CCRN exam eligible
- 15-bed unit with private rooms
- 1:3 Patient Ratio
- Full Time Days / 12-hour shifts
- Weekend and Holiday rotation
- Benefits effective first day of month following start date
- 401K with match
- Tuition Assistance - Eligible day-one employment
- This is a tool to empower nurses to work at the top of their license and own their career progression.
- The BJC RN Career Ladder promotes professional development, leadership, collaboration, education and service excellence and gives staff the opportunity to continue doing what they do best - caring for patients - while having the opportunity to advance to the next step in their career.
- Moves to higher ladder levels will result in a percentage increase of current pay that aligns with the new job description.
Overview
Barnes-Jewish Hospital at Washington University Medical Center is the largest hospital in Missouri and is ranked as one of the nation's top hospitals by U.S. News & World Report. Barnes-Jewish Hospital's staff is composed of full-time academic faculty and community physicians of Washington University School of Medicine, supported by a house staff of residents, interns, fellows and other medical professionals. Recognizing its excellence in nursing care, Barnes-Jewish Hospital was the first adult hospital in Missouri to be certified as a Magnet Hospital by the American Nurses Credentialing Center.
Acute Care Medicine manage patients with a full range of clinical issues-from significant blood dyscrasias, advanced endocrine pathology, heart and renal failure, GI conditions, infectious diseases, asthma, and a multitude of other conditions and diseases. Because of our patient acuity, we provide advanced training to bring new nurses to the highest level of functioning. Each unit is lead by a clinical manager and lead charge nurse. The unit is supported by an advanced practice nurse. Additionally each unit is assigned a case manager, social worker, physical therapist, dietitian, and pharmacist. This multidisciplinary team works in conjunction with the physicians, nurses, and patient care technicians to provide quality patient care.
Preferred Qualifications
Role Purpose
Provides direct patient care activities including assessment, diagnosis, planning implementation, and evaluation within the guidelines of the standards of nursing care.
Responsibilities
- Promotes patient and family centered care in a healing environment. Educates patients and their families on how to manage their illness or injury, including post treatment home care needs and medication administration.
- Participates in activities that promote patient safety, quality and regulatory compliance. Participates in professional development.
- Develops, implements, and documents individual plans of care with defined goals in collaboration with other members of the interprofessional team and patient, family or caregiver in accordance with the established guidelines and standards of nursing care. Proactively plans and ensures communication of the plan of care across the continuum of care.
- Uses critical nursing skills to assess and evaluate physical, psychosocial, and emotional needs according to standards of care. Assess patient preferences and barriers to involvement in care, including their values, emotional, spiritual, cultural, and population-specific needs.
- BJC has determined this is a safety-sensitive position. The ability to work in a constant state of alertness and in a safe manner is an essential function of this job.
Minimum Requirements
Education
- Nursing Diploma/Associate's
- Nursing
Experience
- No Experience
Supervisor Experience
- No Experience
Licenses & Certifications
- RN
Preferred Requirements
Education
- Bachelor's Degree
- Nursing
Experience
- <2 years
Benefits and Legal Statement
BJC Total Rewards
At BJC we’re committed to providing you and your family with benefits and resources to help you manage your physical, emotional, social and financial well-being.
- Comprehensive medical, dental, vison, life insurance, and legal services available first day of the month after hire date
- Disability insurance* paid for by BJC
- Annual 4% BJC Automatic Retirement Contribution
- 401(k) plan with BJC match
- Tuition Assistance available on first day
- BJC Institute for Learning and Development
- Health Care and Dependent Care Flexible Spending Accounts
- Paid Time Off benefit combines vacation, sick days, holidays and personal time
- Adoption assistance
To learn more, go to our Benefits Summary.
- Not all benefits apply to all jobs
The above information on this description has been designed to indicate the general nature and level of work performed by employees in this position. It is not designed to contain or be interpreted as an exhaustive list of all responsibilities, duties and qualifications required of employees assigned to this job. Equal Opportunity Employer
See All 220+ Clinical Nurse Jobs in St. Louis
Find roles in St. Louis that match your experience and apply in just a few clicks.
Find Clinical Nurse JobsClinical Nurse Job Market in St. Louis
Who's Hiring
- BJC HealthCare166

- Washington University in St. Louis29

- SSM Health12

- Mercy5

- IQVIA2

Top Industries Hiring
- Healthcare & Medical Services
Clinical Nurse Jobs in St. Louis: Frequently Asked Questions
How do I get a clinical nurse job in St. Louis?
The strongest hiring in St. Louis clusters around the health systems anchoring the Central West End, the VA campus in Midtown, and the network of community hospitals and outpatient clinics in South City and the inner suburbs. Candidates with experience in med-surg, ICU, or oncology move fastest here. Tailoring your application to the specific unit and patient population a facility serves gives you a clear edge over generic submissions.
Which companies hire clinical nurses in St. Louis?
St. Louis clinical nurse roles are posted by BJC HealthCare, Washington University in St. Louis, and SSM Health and others right now, based on current listings on Migrate Mate as of November 2026. St. Louis draws from a mix of large academic medical centers, regional hospital networks, and a growing number of multispecialty outpatient groups that hire nurses across multiple care settings.
Are there remote clinical nurse jobs in St. Louis?
Yes, though remote work is limited for clinical nurses given the hands-on nature of direct patient care. About 83% of clinical nurse openings tied to St. Louis are remote or hybrid as of November 2026, concentrated in utilization review, case management, and telehealth triage roles. Those functions are the most realistic targets if you want flexibility without leaving nursing entirely.
How can I get a clinical nurse job in St. Louis with little or no experience?
The most realistic entry path in St. Louis is a new-graduate residency program at one of the larger health systems in the Central West End or at a community hospital in the surrounding metro. These structured programs pair new nurses with mentors and rotate them through high-volume units. Acute care, long-term care facilities, and rehabilitation centers in the inner suburbs also hire new graduates more readily than specialty units and are a strong starting point for building clinical hours.
Which industries hire the most clinical nurses in St. Louis?
The sectors hiring the most clinical nurses in St. Louis are Healthcare & Medical Services, based on current listings on Migrate Mate as of November 2026. St. Louis has a dense concentration of academic medical centers, specialty hospitals, and a well-established network of outpatient and home health providers that collectively sustain consistent nursing demand across the metro.
Related Jobs in Missouri
See All 220+ Clinical Nurse Jobs in St. Louis
Find roles in St. Louis that match your experience and apply in just a few clicks.
Find Clinical Nurse Jobs