Clinical Nurse Jobs in Durham, NC
Clinical Nurse jobs in Durham, North Carolina concentrate in the Duke University Hospital corridor, downtown Durham, and the Research Triangle Park edge near RTP, across academic medical centers, community health systems, and specialty clinics, with demand running strong across critical care, oncology, and emergency settings. Employers hiring right now include Duke Health. Scan the live roles below and apply to whichever ones fit.
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At Duke Health, we're driven by a commitment to compassionate care that changes the lives of patients, their loved ones, and the greater community. No matter where your talents lie, join us and discover how we can advance health together.
About Duke University Hospital
Pursue your passion for caring with Duke University Hospital in Durham, North Carolina, which is consistently ranked among the best in the United States. The largest of the four Duke Healthhospitals with 1062 patient beds, it features comprehensive diagnostic and therapeutic facilities, including a regional emergency/trauma center, an endo-surgery center, and more.
Duke Nursing Highlights:
- Duke University Health System is designated as a Magnet organization
- Nurses from each hospital are consistently recognized each year as North Carolina's Great 100 Nurses.
- Duke University Health System was awarded the American Board of Nursing Specialties Award for Nursing Certification Advocacy for being strong advocates of specialty nursing certification.
- Duke University Health System has 6000 + registered nurses
- Quality of Life: Living in the Triangle!
- Relocation Assistance (based on eligibility)
Occ Summary
Independently plan and provide professional nursing care for patients in accordance with physician orders and established policies and procedures. Provide nursing services to patients and families in accordance with the scope of the RN as defined by the North Carolina Board of Nursing. Nurses hired into this limited benefited classification will commit to work a minimum number of hours in a designated inpatient nursing department. Compensation is a flat rate that is based on years of experience.
Work Performed
Plan, provide, supervise and document professional nursing care utilizing the nursing process for patients in accordance with physician orders and established policies and procedures. Use professional nursing judgment to individualize the plan of care based on assessment of the patient's baseline needs and response to care. Delegate tasks and supervise the activities of other licensed and unlicensed care providers. Assist other nursing personnel in the delivery of nursing care and act as team leader or charge nurse for a group of patients or an entire unit as assigned. Monitor and initiate corrective action to maintain the environment of care including equipment and materialresources. Participate in own professional development by maintaining required competencies, identifying learning needs and seeking appropriate assistance or educational offerings. Act as preceptor and support the development of other staff and formal learners. Participate in the identification of clinical or operational performance improvement opportunities and in performance improvement activities. Perform other related duties incidental to the work described herein.
Knowledge, Skills and Abilities
Knowledge of scope of the registered nurse, licensed practical nurse and unlicensed staff Knowledge of and appropriate application of the nursing process Knowledge of professional theory, practice and procedure Ability to assess nursing needs of acute and chronically ill patients and their families Ability to independently seek out resources and work collaboratively Ability to establish and maintain effective working relationships Ability to communicate clearly with patients, families, visitors, healthcare team, physicians, administrators, leadership and others Ability to teach patients and families in accordance with the nursing plan of care Ability to use sensory and cognitive functions to process and prioritize information, treatment, and follow-up Ability to use fine motor skills Competent in BLS and/or other specialized life support requirements designated by work area Ability to record activities, document assessments, plan of care, interventions, evaluation and re-evaluation of patient status Ability to use computer and learn new software programs Able to document and communicate pertinent information using computer and/or paper documentation tools Ability to navigate the entity to provide clinical care for patients Abilityto withstand prolonged standing and walking Ability to remain focused and organized Working knowledge of procedures and techniques involved in administering routine and special treatments to patients Working knowledge of infection control procedures and safety precautions Working knowledge and completion of appropriate The Joint Commission (TJC) and other regulatory requirements Pre-employment Physical Capacity Testing Required
Level Characteristics
N/A
Minimum Qualifications
Education
Work requires graduation from an accredited Associate's Degree in Nursing or Nursing Diploma program.
Experience
2 years of appropriate clinical experience required
Degrees, Licensures, Certifications
Must have current or compact RN licensure in the state of North Carolina. BLS required.
Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.
At Duke Health, we're driven by a commitment to compassionate care that changes the lives of patients, their loved ones, and the greater community. No matter where your talents lie, join us and discover how we can advance health together.
About Duke University Hospital
Pursue your passion for caring with Duke University Hospital in Durham, North Carolina, which is consistently ranked among the best in the United States. The largest of the four Duke Healthhospitals with 1062 patient beds, it features comprehensive diagnostic and therapeutic facilities, including a regional emergency/trauma center, an endo-surgery center, and more.
Duke Nursing Highlights:
- Duke University Health System is designated as a Magnet organization
- Nurses from each hospital are consistently recognized each year as North Carolina's Great 100 Nurses.
- Duke University Health System was awarded the American Board of Nursing Specialties Award for Nursing Certification Advocacy for being strong advocates of specialty nursing certification.
- Duke University Health System has 6000 + registered nurses
- Quality of Life: Living in the Triangle!
- Relocation Assistance (based on eligibility)
Occ Summary
Independently plan and provide professional nursing care for patients in accordance with physician orders and established policies and procedures. Provide nursing services to patients and families in accordance with the scope of the RN as defined by the North Carolina Board of Nursing. Nurses hired into this limited benefited classification will commit to work a minimum number of hours in a designated inpatient nursing department. Compensation is a flat rate that is based on years of experience.
Work Performed
Plan, provide, supervise and document professional nursing care utilizing the nursing process for patients in accordance with physician orders and established policies and procedures. Use professional nursing judgment to individualize the plan of care based on assessment of the patient's baseline needs and response to care. Delegate tasks and supervise the activities of other licensed and unlicensed care providers. Assist other nursing personnel in the delivery of nursing care and act as team leader or charge nurse for a group of patients or an entire unit as assigned. Monitor and initiate corrective action to maintain the environment of care including equipment and materialresources. Participate in own professional development by maintaining required competencies, identifying learning needs and seeking appropriate assistance or educational offerings. Act as preceptor and support the development of other staff and formal learners. Participate in the identification of clinical or operational performance improvement opportunities and in performance improvement activities. Perform other related duties incidental to the work described herein.
Knowledge, Skills and Abilities
Knowledge of scope of the registered nurse, licensed practical nurse and unlicensed staff Knowledge of and appropriate application of the nursing process Knowledge of professional theory, practice and procedure Ability to assess nursing needs of acute and chronically ill patients and their families Ability to independently seek out resources and work collaboratively Ability to establish and maintain effective working relationships Ability to communicate clearly with patients, families, visitors, healthcare team, physicians, administrators, leadership and others Ability to teach patients and families in accordance with the nursing plan of care Ability to use sensory and cognitive functions to process and prioritize information, treatment, and follow-up Ability to use fine motor skills Competent in BLS and/or other specialized life support requirements designated by work area Ability to record activities, document assessments, plan of care, interventions, evaluation and re-evaluation of patient status Ability to use computer and learn new software programs Able to document and communicate pertinent information using computer and/or paper documentation tools Ability to navigate the entity to provide clinical care for patients Abilityto withstand prolonged standing and walking Ability to remain focused and organized Working knowledge of procedures and techniques involved in administering routine and special treatments to patients Working knowledge of infection control procedures and safety precautions Working knowledge and completion of appropriate The Joint Commission (TJC) and other regulatory requirements Pre-employment Physical Capacity Testing Required
Level Characteristics
N/A
Minimum Qualifications
Education
Work requires graduation from an accredited Associate's Degree in Nursing or Nursing Diploma program.
Experience
2 years of appropriate clinical experience required
Degrees, Licensures, Certifications
Must have current or compact RN licensure in the state of North Carolina. BLS required.
Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.
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Who's Hiring
Clinical Nurse Jobs in Durham: Frequently Asked Questions
How do I get a clinical nurse job in Durham?
Focus your search on Durham's academic medical centers, community hospitals, and the network of specialty clinics that cluster near Duke University Hospital and downtown. Candidates with experience in critical care, oncology, or emergency nursing move fastest in this market. Tailoring your application to the specific unit or service line, and showing familiarity with the patient population those Durham systems serve, gives you a clear edge over generic applicants.
Which companies hire clinical nurses in Durham?
Employers hiring clinical nurses in Durham right now include Duke Health, based on current listings on Migrate Mate as of October 2026. Durham's hiring landscape is anchored by large academic health systems alongside community health organizations and outpatient specialty practices serving the broader Triangle region.
Are there remote clinical nurse jobs in Durham?
Yes, though with an important qualifier: clinical nursing is predominantly a hands-on, bedside role, so fully remote openings are uncommon. About 67% of clinical nurse openings tied to Durham are remote or hybrid as of October 2026, and those positions tend to concentrate in telephonic triage, care management, and utilization review roles rather than direct patient care.
How can I get a clinical nurse job in Durham with little or no experience?
The most realistic entry path in Durham is applying to new-graduate residency or transition-to-practice programs offered by the academic health systems in the area, which are designed specifically to bring early-career nurses onto inpatient units with structured mentorship. Community health centers and outpatient clinics near downtown Durham also hire nurses with limited hospital experience for lower-acuity roles, and those positions frequently serve as stepping stones to larger system employment.
Related Jobs in North Carolina
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