Mid Level Clinical Operations Director Jobs

Mid level clinical operations director jobs go to professionals ready to own site operations end to end, guide junior coordinators, and make protocol-level decisions without waiting for senior sign-off. Roles run across Healthcare & Medical Services, Education, and Biotechnology & Pharmaceuticals, with a strong mix of on-site, hybrid, and remote positions, and employers like AccentCare, Kindred Hospitals, and UCHealth hiring at this level now.

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Overview

Open roles17
Top stateCalifornia
Top employerAccentCare
Top citySan Francisco, CA
Work type78% On-site
Top industryHealthcare

Showing 5 of 17+ Mid Level Clinical Operations Director jobs

City and County of San Francisco
Chief Operating Officer
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City and County of San Francisco
Added 4d ago
Chief Operating Officer
City and County of San Francisco
San Francisco, California
Executive Leadership & C-Suite
Project & Program Management
Human Resources
Business Operations
Compliance & Legal
Project Management
$201k - $256k/yr
On-Site
Bachelor's

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AccentCare
Clinical Operations Director RN, Hospice
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AccentCare
Added 1w ago
Clinical Operations Director RN, Hospice
AccentCare
Renton, Washington
Caregiving & Elderly Support
Healthcare Administration
Nursing
Patient Services & Wellbeing
$140k - $170k/yr
Bachelor's degree
10,000+

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Select Medical
Chief Operating Officer
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Select Medical
Added 1w ago
Chief Operating Officer
Select Medical
Yorktown, Virginia
Executive Leadership & C-Suite
Healthcare Administration
Human Resources
Compliance & Legal
$130k - $150k/yr
On-Site
Master's

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Mayo Clinic
Director - Clinical Services, Ambulance Operations
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Mayo Clinic
Added 1mo ago
Director - Clinical Services, Ambulance Operations
Mayo Clinic
Jacksonville, Florida
Healthcare Administration
Mental & Behavioral Health
Social Work & Counseling
Master's degree in business
10,000+

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Columbia University
Senior Director, Clinical Trials Strategy and Operations
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Columbia University
Added 1mo ago
Senior Director, Clinical Trials Strategy and Operations
Columbia University
New York, New York
Clinical Trials & Medical Research
Healthcare Administration
Project & Program Management
Clinical Trials
Project Management
$175k - $225k/yr
On-Site
Bachelor's
10,000+

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Mid Level Clinical Operations Director Job Market

Who's Hiring

AccentCare
AccentCare2 open roles
Kindred Hospitals
Kindred Hospitals2 open roles
UCHealth
UCHealth1 open role

Top Industries Hiring

  • Healthcare & Medical Services
  • Education
  • Biotechnology & Pharmaceuticals
  • Consulting & Professional Services
  • Technology & Software

Mid Level Clinical Operations Director Jobs: Frequently Asked Questions

How do I get a mid level clinical operations director job?

Position your experience around ownership, not just participation. Highlight trials or programs you managed from startup through closeout, decisions you made independently, and any cross-functional coordination you led. Applications that show you can run a site or function without heavy oversight stand out. Tailor your resume to reflect scope, not just tasks, and demonstrate measurable outcomes like enrollment targets met or audit-ready documentation.

Which companies hire mid level clinical operations directors?

Companies hiring mid level clinical operations directors right now include AccentCare, Kindred Hospitals, and UCHealth, based on current listings on Migrate Mate as of August 2026. Hiring at this level comes from a broad range of organizations, including contract research organizations, pharmaceutical sponsors, biotechs, and health systems that run ongoing or expanding clinical programs.

Are there remote mid level clinical operations director jobs?

Yes, though availability varies by employer and program type. About 22% of mid level clinical operations director openings are remote or hybrid as of August 2026, with remote roles more common in oversight-focused positions and hybrid arrangements typical where site visits or cross-functional team coordination require some in-person presence.

How do I move up to a mid level clinical operations director role?

The path typically involves deepening hands-on experience with clinical site management, trial logistics, or regulatory compliance until you can point to projects you owned rather than supported. Building a record of independent problem-solving, mentoring peers informally, and driving measurable outcomes like protocol adherence or site performance prepares you to step into mid level scope and responsibility.

Which industries hire the most mid level clinical operations directors?

Mid Level clinical operations director roles concentrate in Healthcare & Medical Services, Education, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of August 2026. These sectors drive consistent demand because they run large, ongoing clinical programs that require experienced professionals to manage site operations, vendor relationships, and regulatory timelines at a working level.