Clinical Operations Director Jobs in South Dakota
Clinical Operations Director jobs in South Dakota are open across Rapid City, Sioux Falls, and Aberdeen and other South Dakota metros, with employers like Monument Health, Sanford Health, and Sioux Center Health hiring at every experience level. Find a role that fits below and apply directly.
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Showing 5 of 90+ Clinical Operations Director jobs
Careers With Purpose
Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland.
Facility: Chamberlain Medical Center
Location: Chamberlain, SD
Address: 300 S Byron Blvd, Chamberlain, SD 57325, USA
Shift: 8 Hours - Day Shifts
Job Schedule: Full time
Weekly Hours: 40.00
Job Summary
Responsible for providing clinical and administrative leadership in a hospital, nursing home, or other medical facility to maintain standards of patient care. This role has a larger size, scope, or complexity. Implements the vision, mission, and strategic plan of clinical services and the system. Assists in the development, planning, and implementation of a systems approach to improve and maintain standards in clinical patient care, patient safety, and health outcomes. Maintains communication and addresses the rapidly changing healthcare environment in which clinical services are delivered across the system. Leads the development and execution of clinical programs, policies, procedures and protocols ensuring system integration and adherence. Monitors operations of nursing staff and ensures compliance with regulations on organizational and governmental standards and practices.
Qualifications
For Rural Health Network facilities only, employees hired after January, 2025, who do not possess a Bachelor’s degree in the required field, leadership may consider an educational plan with proven continuous action toward achieving a Bachelor’s degree in Nursing within five years of hire into position. Approval from the Nursing Executive for the market is required in order to waive the bachelor degree requirement at time of hire. Additionally for Rural Health Network facilities, for current employees, leadership may have considered acceptable qualifications and work experience equivalency based on facility size, rural market, and business need, prior to new Sanford education requirements.
Minimum five years nursing experience. Two years’ management/leadership experience preferred. Thorough knowledge of the nursing practice act and standards of nursing care, and a working knowledge of administrative and management techniques.
Currently holds an unencumbered RN license with the State Board of Nursing where the practice of nursing is occurring and/or possess multistate licensure if in a Nurse Licensure Compact (NLC) state. Obtains and subsequently maintains required department specific competencies and certifications.
Benefits
Sanford offers an attractive benefits package for qualifying full-time and part-time employees. Depending on eligibility, a variety of benefits include health insurance, dental insurance, vision insurance, life insurance, a 401(k) retirement plan, work/life balance benefits, and a generous time off package to maintain a healthy home-work balance. For more information about Total Rewards, visit https://sanfordcareers.com/benefits.
Sanford is an EEO/AA Employer M/F/Disability/Vet. If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-673-0854 or send an email to talent@sanfordhealth.org.
Sanford has a Drug Free Workplace Policy. An accepted offer will require a drug screen and pre-employment background screening as a condition of employment.
Req Number: R-0264006
Job Function: Nursing
Featured: No
Careers With Purpose
Sanford Health, the largest rural health system in the United States, is dedicated to transforming the health care experience and providing access to world-class health care in America’s heartland.
Facility: Chamberlain Medical Center
Location: Chamberlain, SD
Address: 300 S Byron Blvd, Chamberlain, SD 57325, USA
Shift: 8 Hours - Day Shifts
Job Schedule: Full time
Weekly Hours: 40.00
Job Summary
Responsible for providing clinical and administrative leadership in a hospital, nursing home, or other medical facility to maintain standards of patient care. This role has a larger size, scope, or complexity. Implements the vision, mission, and strategic plan of clinical services and the system. Assists in the development, planning, and implementation of a systems approach to improve and maintain standards in clinical patient care, patient safety, and health outcomes. Maintains communication and addresses the rapidly changing healthcare environment in which clinical services are delivered across the system. Leads the development and execution of clinical programs, policies, procedures and protocols ensuring system integration and adherence. Monitors operations of nursing staff and ensures compliance with regulations on organizational and governmental standards and practices.
Qualifications
For Rural Health Network facilities only, employees hired after January, 2025, who do not possess a Bachelor’s degree in the required field, leadership may consider an educational plan with proven continuous action toward achieving a Bachelor’s degree in Nursing within five years of hire into position. Approval from the Nursing Executive for the market is required in order to waive the bachelor degree requirement at time of hire. Additionally for Rural Health Network facilities, for current employees, leadership may have considered acceptable qualifications and work experience equivalency based on facility size, rural market, and business need, prior to new Sanford education requirements.
Minimum five years nursing experience. Two years’ management/leadership experience preferred. Thorough knowledge of the nursing practice act and standards of nursing care, and a working knowledge of administrative and management techniques.
Currently holds an unencumbered RN license with the State Board of Nursing where the practice of nursing is occurring and/or possess multistate licensure if in a Nurse Licensure Compact (NLC) state. Obtains and subsequently maintains required department specific competencies and certifications.
Benefits
Sanford offers an attractive benefits package for qualifying full-time and part-time employees. Depending on eligibility, a variety of benefits include health insurance, dental insurance, vision insurance, life insurance, a 401(k) retirement plan, work/life balance benefits, and a generous time off package to maintain a healthy home-work balance. For more information about Total Rewards, visit https://sanfordcareers.com/benefits.
Sanford is an EEO/AA Employer M/F/Disability/Vet. If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-673-0854 or send an email to talent@sanfordhealth.org.
Sanford has a Drug Free Workplace Policy. An accepted offer will require a drug screen and pre-employment background screening as a condition of employment.
Req Number: R-0264006
Job Function: Nursing
Featured: No
See All 90 Clinical Operations Director Jobs in South Dakota
Find roles in South Dakota that match your experience and apply in just a few clicks.
Find JobsClinical Operations Director Jobs by City in South Dakota
Where South Dakota roles are concentrated, by current openings.
Clinical Operations Director Job Market in South Dakota
A snapshot from current South Dakota openings, updated as new roles post.
Who's Hiring
- Monument Health30
- Sanford Health28
- Sioux Center Health15
- Sanford Bismarck5
- NVA4
Top Industries Hiring
- Healthcare & Medical Services80
- Non-Profit & Social Services5
- Animal Care & Pet Services4
- Agriculture & Farming3
- Science & Research1
What South Dakota Employers Look For
The qualifications that appear most often in clinical operations director jobs across South Dakota.
- Bachelor's or advanced degree in life sciences, nursing, or a related clinical field
- Extensive experience managing Phase I through Phase IV clinical trials end to end
- Deep knowledge of ICH-GCP guidelines, FDA regulations, and applicable international standards
- Proven experience selecting, overseeing, and managing contract research organizations
- Proficiency with electronic data capture systems such as Medidata Rave or Veeva Vault
- Strong cross-functional leadership and budget management experience across global clinical programs
Clinical Operations Director Jobs in South Dakota: Frequently Asked Questions
How many clinical operations director jobs are there in South Dakota?
There are 90+ clinical operations director openings in South Dakota on Migrate Mate as of June 2026, with the most roles in Rapid City, Sioux Falls, and Aberdeen. New positions post regularly as employers across South Dakota hire.
Which South Dakota cities have the most clinical operations director jobs?
Rapid City, Sioux Falls, and Aberdeen have the most clinical operations director openings in South Dakota right now, with additional roles spread across smaller metros statewide.
Which companies hire clinical operations directors in South Dakota?
Employers hiring clinical operations directors in South Dakota include Monument Health, Sanford Health, and Sioux Center Health, based on current listings on Migrate Mate as of June 2026.
Are there remote clinical operations director jobs in South Dakota?
Yes. About 0% of clinical operations director openings tied to South Dakota are remote or hybrid as of June 2026. The rest are on-site roles based in South Dakota metros.
How do I apply for clinical operations director jobs in South Dakota?
You can apply to clinical operations director jobs in South Dakota directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Dakota location, then apply to each one that fits.
See All 90 Clinical Operations Director Jobs in South Dakota
Find roles in South Dakota that match your experience and apply in just a few clicks.
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