Clinical Operations Lead Jobs in Kansas City, MO
Clinical Operations Lead jobs in Kansas City are concentrated in the Country Club Plaza corridor, the Crossroads Arts District health tech cluster, and the suburban campuses in Overland Park and Lenexa, with demand running strongest across health systems, life sciences, and clinical research organizations. Employers actively hiring include Catalent Pharma Solutions, Quest Diagnostics, and Kansas City National Security Campus. See the openings below and apply to the ones that match your experience.
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Showing 5 of 53+ Clinical Operations Lead jobs
- Strong SME knowledge in Healthcare Claims Processing lifecycle
- Expertise in EDI formats – 837 (P/I/D), 835, 834
- Hands-on experience in Facets (Claims + Enrollment modules)
- Proficiency in Azure DevOps (ADO) for QA tracking
- Knowledge of HIPAA compliance and payer systems
- 8+ years of experience in Healthcare QA/Testing
- 4+ years of experience as Test Lead in Facets projects
- Deep understanding of Claims Adjudication & Payment workflows
- Experience in handling claims denials, adjustments, and reprocessing
- Strong exposure to EDI claim and remittance transactions
- Experience in mocking and validating EDI files (837/835/834)
- Knowledge of ITS claims processing (SF, DF, RF)
- Experience in Member Enrollment workflows (Medicaid, Medicare, ACA)
- Understanding of Billing lifecycle for member enrollment
- Hands-on experience with ADO Test Plans, Test Suites, and Defect tracking
- Ability to perform data validation and reconciliation activities
- Strong experience in functional and end-to-end testing
- Familiarity with Agile/Scrum methodologies
- Excellent stakeholder communication and coordination skills
- Experience in risk identification, defect triage, and RCA
- Lead end-to-end testing for Claims, Enrollment, and Billing modules
- Act as SME for Claims Processing and EDI transactions
- Validate Facets Claims and Membership workflows
- Design and execute test strategies, test plans, and test cases
- Perform EDI validation (837, 835, 834) including mock data creation
- Manage defect lifecycle, triage, and resolution tracking in ADO
- Ensure HIPAA compliance in all testing activities
- Validate ITS claims processing across SF, DF, RF flows
- Drive quality metrics, reporting, and release sign-offs
- Collaborate with business, development, and partner teams for E2E validation
- Leading and Mentoring team members
- Strong problem-solving and critical thinking
- Ability to work with minimal supervision
- Documentation and knowledge sharing
- Excellent communication
- Strong SME knowledge in Healthcare Claims Processing lifecycle
- Expertise in EDI formats – 837 (P/I/D), 835, 834
- Hands-on experience in Facets (Claims + Enrollment modules)
- Proficiency in Azure DevOps (ADO) for QA tracking
- Knowledge of HIPAA compliance and payer systems
- 8+ years of experience in Healthcare QA/Testing
- 4+ years of experience as Test Lead in Facets projects
- Deep understanding of Claims Adjudication & Payment workflows
- Experience in handling claims denials, adjustments, and reprocessing
- Strong exposure to EDI claim and remittance transactions
- Experience in mocking and validating EDI files (837/835/834)
- Knowledge of ITS claims processing (SF, DF, RF)
- Experience in Member Enrollment workflows (Medicaid, Medicare, ACA)
- Understanding of Billing lifecycle for member enrollment
- Hands-on experience with ADO Test Plans, Test Suites, and Defect tracking
- Ability to perform data validation and reconciliation activities
- Strong experience in functional and end-to-end testing
- Familiarity with Agile/Scrum methodologies
- Excellent stakeholder communication and coordination skills
- Experience in risk identification, defect triage, and RCA
- Lead end-to-end testing for Claims, Enrollment, and Billing modules
- Act as SME for Claims Processing and EDI transactions
- Validate Facets Claims and Membership workflows
- Design and execute test strategies, test plans, and test cases
- Perform EDI validation (837, 835, 834) including mock data creation
- Manage defect lifecycle, triage, and resolution tracking in ADO
- Ensure HIPAA compliance in all testing activities
- Validate ITS claims processing across SF, DF, RF flows
- Drive quality metrics, reporting, and release sign-offs
- Collaborate with business, development, and partner teams for E2E validation
- Leading and Mentoring team members
- Strong problem-solving and critical thinking
- Ability to work with minimal supervision
- Documentation and knowledge sharing
- Excellent communication
See All 53 Clinical Operations Lead Jobs in Kansas City
Find roles in Kansas City that match your experience and apply in just a few clicks.
Find Clinical Operations Lead JobsClinical Operations Lead Job Market in Kansas City
Who's Hiring
- Catalent Pharma Solutions4
- Quest Diagnostics3
- Kansas City National Security Campus3
- Deloitte2
- Burns & McDonnell2
Top Industries Hiring
- Consulting & Professional Services7
- Construction & Real Estate5
- Technology & Software4
- Manufacturing3
- Science & Research3
Clinical Operations Lead Jobs in Kansas City: Frequently Asked Questions
How do I get a clinical operations lead job in Kansas City?
Focus on Kansas City's health system networks and the growing clinical research organization presence anchored around the University of Kansas Health System and Children's Mercy. Candidates with experience coordinating multi-site trials or managing regulatory submissions stand out locally. Targeting mid-size CROs and specialty pharma companies in the Overland Park and Lenexa corridors, where back-office clinical functions concentrate, gives you a practical foothold in this market.
Which companies hire clinical operations leads in Kansas City?
Kansas City clinical operations lead roles are posted by Catalent Pharma Solutions, Quest Diagnostics, and Kansas City National Security Campus and others right now, based on current listings on Migrate Mate as of July 2026. The local employer mix leans toward integrated health systems, regional CROs, and medical device companies with Midwest operational hubs.
Are there remote clinical operations lead jobs in Kansas City?
Yes, though it depends heavily on the function: protocol management, data oversight, and vendor coordination roles tend to go remote, while site-facing and facility operations roles remain on-site. About 26% of clinical operations lead openings tied to Kansas City are remote or hybrid as of July 2026, with the strongest remote availability in CRO and health tech companies headquartered in the suburban corridors.
How can I get a clinical operations lead job in Kansas City with little or no experience?
The most realistic path in Kansas City is moving up from a clinical coordinator or study coordinator role within one of the city's major health networks or regional CROs. Entry-level clinical operations positions at organizations in the Overland Park life sciences corridor regularly serve as the on-ramp, and candidates who demonstrate familiarity with GCP compliance, IRB submission workflows, and site management tools tend to advance into lead roles faster than those without that operational grounding.
Which industries hire the most clinical operations leads in Kansas City?
Most clinical operations lead openings in Kansas City sit in Consulting & Professional Services, Construction & Real Estate, and Technology & Software, per current listings on Migrate Mate as of July 2026. Kansas City's concentration of integrated health systems and its expanding life sciences corridor in Johnson County drive the bulk of that demand.
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See All 53 Clinical Operations Lead Jobs in Kansas City
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