Primary Care Physician Jobs in Missouri

Primary Care Physician jobs in Missouri are in strong and consistent demand, concentrated across community health centers, large integrated hospital systems, rural health networks, and federally qualified health centers serving underserved populations. The heaviest hiring activity is in Kansas City, St. Louis, and Springfield, where major employers such as BJC HealthCare, Mercy Health, and Saint Luke's Health System maintain deep and ongoing physician recruiting pipelines. Family medicine, internal medicine, and geriatric primary care are the most sought-after practice areas across the state. See the openings below and apply to the ones that match your experience.

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Overview

Open roles46
Top employerMercy
Top citySt. Louis, MO
Cities hiring25
Work type91% On-site
Top industryHealthcare

Showing 5 of 46+ Primary Care Physician jobs

Purple Cow Recruiting
Primary Care Physician | Value-Based Care | $174K–$375K
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Purple Cow Recruiting
Added 4d ago
Primary Care Physician | Value-Based Care | $174K–$375K
Purple Cow Recruiting
St. Louis, Missouri
Healthcare Administration
Patient Services & Wellbeing
Physicians
$174k - $375k/yr
On-Site

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Purple Cow Recruiting
Primary Care Physician | Value-Based Care | $174K–$375K
We won't show you this job again
Purple Cow Recruiting
Added 4d ago
Primary Care Physician | Value-Based Care | $174K–$375K
Purple Cow Recruiting
Missouri
Healthcare Administration
Patient Services & Wellbeing
Physicians
$174k - $375k/yr
On-Site

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Mercy
Nurse Practitioner or Physician Assistant - Primary Care 365 - Mercy Virtual Care Center
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Mercy
Added 4d ago
Nurse Practitioner or Physician Assistant - Primary Care 365 - Mercy Virtual Care Center
Mercy
Chesterfield, Missouri
Healthcare Administration
Patient Services & Wellbeing
Physicians
Remote (US)
10,000+

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Purple Cow Recruiting
Primary Care Physician | Adults 65+ | $235K–$260K
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Purple Cow Recruiting
Added 5d ago
Primary Care Physician | Adults 65+ | $235K–$260K
Purple Cow Recruiting
Gladstone, Missouri
Clinical Support
Healthcare Administration
Medical Specialists
$235k - $300k/yr

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Mercy
Nurse Practitioner or Physician Assistant - Adult Primary Care - Mercy O'Fallon Winding Woods
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Mercy
Added 6d ago
Nurse Practitioner or Physician Assistant - Adult Primary Care - Mercy O'Fallon Winding Woods
Mercy
O'Fallon, Missouri
Clinical Support
Healthcare Administration
Medical Specialists
10,000+

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See All 46 Primary Care Physician Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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Primary Care Physician Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

St. Louis
10 jobs
Chesterfield
5 jobs
Saint Peters
3 jobs
Columbia
2 jobs
O'Fallon
2 jobs
Gladstone
2 jobs
Florissant
2 jobs
Jefferson City
2 jobs
Dexter
1 job

Primary Care Physician Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

Mercy
Mercy9 open roles
St. Luke's Hospital (MO)
St. Luke's Hospital (MO)7 open roles
Purple Cow Recruiting
Purple Cow Recruiting5 open roles

Top Industries Hiring

  • Healthcare & Medical Services
  • Education
  • Staffing & Recruiting

What Missouri Employers Look For

The qualifications that appear most often in primary care physician jobs across Missouri.

  • Active Missouri medical license issued by the Missouri State Board of Registration for the Healing Arts
  • Doctor of Medicine or Doctor of Osteopathic Medicine degree from an accredited program
  • Completion of an accredited residency in family medicine, internal medicine, or a related primary care field
  • Board certification or active board eligibility in a primary care specialty
  • Current DEA registration and valid controlled substance prescribing authority in Missouri
  • Experience with electronic health records systems such as Epic or Cerner in a clinical setting

Primary Care Physician Jobs in Missouri: Frequently Asked Questions

How do you become a primary care physician in Missouri?

To practice as a primary care physician in Missouri, you must obtain a medical license through the Missouri State Board of Registration for the Healing Arts, which requires a medical degree from an accredited institution, completion of an approved residency program, and passing scores on the USMLE or COMLEX. Most Missouri health systems also require board certification in a primary care specialty such as family medicine or internal medicine before extending an employment offer.

Which companies hire primary care physicians in Missouri?

Companies currently hiring primary care physicians in Missouri include Mercy, St. Luke's Hospital (MO), and Purple Cow Recruiting, per current listings on Migrate Mate as of August 2026. Missouri's large integrated health systems and federally qualified health centers are among the most consistent sources of physician openings across both urban and rural parts of the state.

Which Missouri cities have the most primary care physician jobs?

St. Louis, Chesterfield, and Saint Peters are the Missouri cities with the most primary care physician openings. Kansas City and St. Louis drive the bulk of demand through their large hospital systems and academic medical centers, while Springfield and Columbia generate steady hiring through regional health networks and university-affiliated practices that serve surrounding rural communities.

Are there remote primary care physician jobs in Missouri?

Yes, but they're rare. Primary care physicians work directly with patients in clinical settings, which makes fully remote positions uncommon. About 9% of primary care physician openings tied to Missouri are remote or hybrid as of August 2026, with most of those roles concentrated in telemedicine, telephonic triage, or utilization review functions rather than traditional direct patient care.

How can I get hired as a primary care physician in Missouri with little or no experience?

The most realistic entry path is applying directly to residency-to-practice pipeline programs at large Missouri health systems such as BJC HealthCare, Mercy Health, or Federally Qualified Health Centers administered through the Missouri Primary Care Association, which recruit residents nearing graduation. New physicians without independent practice history can also pursue locum tenens assignments at rural Missouri hospitals to build a clinical record, then transition to permanent staff roles. Securing Missouri licensure and board eligibility before applying gives candidates a clear edge over those still pending.

Where can I find and apply to primary care physician jobs in Missouri?

You can find and apply to primary care physician jobs in Missouri on Migrate Mate, which lists current openings across the state. Search the listings, identify roles that match your specialty and preferred practice setting, and apply directly to the ones that fit your experience and career goals.

See All 46 Primary Care Physician Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

Find Primary Care Physician Jobs