Senior Level Clinical Operations Supervisor Jobs

Senior level clinical operations supervisor jobs put experienced professionals in charge of clinical program oversight, cross-functional team leadership, and the operational systems that keep trials and care delivery running at scale. Openings are concentrated in Biotechnology & Pharmaceuticals, Education, and Healthcare & Medical Services, with a mix of on-site, remote, and hybrid settings, and employers like Revolution Medicines, Revolution Medicines, and University of Florida hiring at this level now.

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Overview

Open roles358+
Top stateCalifornia
Top employerRevolution Medicines
Top cityRedwood City, CA
Work type79% On-site
Top industryBiotechnology

Showing 5 of 358+ Senior Level Clinical Operations Supervisor jobs

Clinical Assistant Professor
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New 57m ago
Clinical Assistant Professor
The University of Michigan
Ann Arbor, Michigan
Nursing
Medical Specialists
Healthcare Administration
Clinical Support
Physicians
Surgeons
On-Site
Doctorate
10,000+

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Clinical Science Lead
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New 6h ago
Clinical Science Lead
Takeda Pharmaceuticals
Boston, Massachusetts
Clinical Support
Healthcare Administration
Medical Specialists
$177k - $278k/yr
On-Site
Other
10,000+

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Sr. Program Manager, Business Ops
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New 9h ago
Sr. Program Manager, Business Ops
Avalara
Remote
AI (Artificial Intelligence)
Product Management
Technical Product & Program Management
Remote (US)
Bachelor's degree in business
1,001-5,000

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Sr. Director, Clinical Supply
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New 12h ago
Sr. Director, Clinical Supply
Glaukos
Aliso Viejo, California
Project & Program Management
Procurement & Supply Chain
Partnerships & Business Development
Compliance & Legal
Human Resources
Project Management
Supply Chain
Business Development
Compliance & Risk
$210k - $262k/yr
On-Site
Bachelor's
51-200

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Anatomic and Clinical Pathologist
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New 20h ago
Anatomic and Clinical Pathologist
Optum
Houston, Texas
Medical Specialists
Healthcare Administration
Allied Health
Physicians
Laboratory Science
$325k - $544k/yr
On-Site
Doctorate
10,000+

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Senior Level Clinical Operations Supervisor Job Market

Who's Hiring

  • Revolution Medicines54
  • University of Florida18
  • Jobot13
  • University Of Washington12

Top Industries Hiring

  • Biotechnology & Pharmaceuticals107
  • Education77
  • Healthcare & Medical Services77
  • Science & Research18
  • Staffing & Recruiting14

Senior Level Clinical Operations Supervisor Jobs: Frequently Asked Questions

How do I get a senior level clinical operations supervisor job?

Employers at this level look for candidates who have owned clinical workflows end-to-end, not just contributed to them. Demonstrating that you have led cross-site or cross-functional initiatives, managed regulatory submissions, and developed junior staff gives you a clear edge. Tailoring your resume to show scope of accountability, budget ownership, and measurable outcomes in prior supervisor roles is what moves applications forward.

Which companies hire senior level clinical operations supervisors?

Companies hiring senior level clinical operations supervisors right now include Revolution Medicines, Revolution Medicines, and University of Florida, based on current listings on Migrate Mate as of November 2026. At this level, hiring tends to come from large pharmaceutical and biotech firms, contract research organizations, and health systems with active clinical trial or quality improvement programs.

Are there remote senior level clinical operations supervisor jobs?

Yes, though availability varies by employer and the operational scope of the role. About 21% of senior level clinical operations supervisor openings are remote or hybrid as of November 2026, with fully remote roles more common in oversight-focused positions and on-site requirements more frequent for site-level or multi-team supervisory work.

What makes a clinical operations supervisor role senior level?

Senior level roles are defined by scope and ownership rather than task execution. Expectations include leading programs or multiple teams, setting operational standards, contributing to strategy decisions, and mentoring mid-level staff. Senior candidates are accountable for outcomes across the full clinical operations cycle, from protocol implementation through closeout, and are expected to resolve complex issues without escalating routine decisions.

Which industries hire the most senior level clinical operations supervisors?

Senior level clinical operations supervisor roles concentrate in Biotechnology & Pharmaceuticals, Education, and Healthcare & Medical Services, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring at this level because they operate large-scale clinical programs that require experienced supervisors to maintain compliance, manage distributed teams, and sustain operational continuity across complex regulatory environments.