Clinical Project Manager Jobs in Columbia, SC
Clinical Project Manager jobs in Columbia, South Carolina are in strong demand, concentrated in the Midlands Medical Corridor near Palmetto Health and the University of South Carolina Health System, as well as in the Forest Drive and Harbison business districts, across clinical research, healthcare IT, and pharmaceutical sectors. Employers hiring right now include Prisma Health, Lexington Health, and Circle K. See the openings below and apply to the ones that match your experience.
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Join the PruittHealth family, where the health and safety of our workforce is our top priority!
We're not only committed to your career, we're committed to the health and safety of all our nurses. Now is a great time to make a change and join one of the leading providers of post-acute care.
PruittHealth will help you conquer your career goals. At PruittHealth, we are searching for nurses who are committed to serving our residents with care and compassion, and in return, we are committed to supporting your nursing career through annual merit increases, career growth programs, preceptorship, and more.
JOB PURPOSE:
Responsible for creating a culture of excellence and learning among staff, through role modeling, quality education, competency assessment and team building activities. Evaluation of care provided to patients is determined by assessing competency of clinical staff on an ongoing basis, evaluating care provided to patients by bedside observation of quantity and quality of clinical services, assessing staff’s demonstration of proper procedures and attitudes and reviewing medical records and documentation.
KEY RESPONSIBILITIES:
1. Coordinates clinical competency assessment and training needs of clinical staff, based on ongoing evaluation, patient needs and acuity.
2. Provides relevant and creative education for clinical staff on a variety of topics, focusing on development of clinical skills, critical thinking, and interpersonal skills of partners.
3. Participates in the interview and selection process of clinical staff.
4. Completes initial competency assessment of clinical staff during orientation process, annually and as needed.
5. Identified and trains clinical staff who will serve as preceptors for new partners, using train-the-trainer approach. Oversee preceptor program and meet with preceptor team on a regular basis, to ensure that organizational standards, policies and procedures are maintained.
6. Conducts competency assessments to determine partner learning needs based on patient conditions and acuity.
7. Meets regularly with DHS to review learning needs, coordinate training and to implement plans for education and follow-up.
8. Communicates regularly with unit managers regarding new partner orientation and competency status and ongoing educational needs of unit staff.
9. Reviews with DHS outcomes of case mix and clinical meetings, in order to identify clinical learning needs for partners.
10. Participates in performance improvement activities.
11. Serves as Pruitt University system administrator for facility, providing training for partners and promoting ongoing use of this education tool among all partners.
12. Maintains documentation of all partner education in accordance with regulations, policies and procedures.
13. Develops and direct facility orientation program and training for new employees including general orientation to facility policies, procedures, philosophy of care and regulations that govern long term care.
14. Communicates and interpret policies and procedures to nursing staff.
15. Monitors practice for effective implementation.
16. Establishes and implement infection control program designed to provide a safe, sanitary and comfortable environment and to prevent the development and transmission of disease and infection.
17. Conducts infection control surveillance activities to investigate, control and prevent infections in the facility.
18. Provides consultation to all departments on application of infection control principles and procedures to specific situations.
19. Conducts staff training and monitor performance particularly for proper hand washing, isolation techniques and universal precautions.
20. Implements workplace safety programs in the facility including hazard communication, occupational exposure to blood borne pathogens and required record keeping of occupational illnesses and injuries.
21. Maintains material safety data sheets and exposure control plan for blood borne pathogens readily accessible to all staff, 24 hours a day.
22. Coordinates Hepatitis B Vaccination Program and post exposure evaluation and follow up requirement.
23. Maintains confidentiality of employee medical records.
KNOWLEDGE, SKILLS, ABILITIES
- Computer skills including Microsoft Word required, Excel and Power Point preferred.
- Knowledge and use of Adult Learning Principles.
- Work history should document volunteer or paid teaching experiences including competency assessment of skills.
- Demonstrates excellent clinical assessment skills and ability to teach these skills to facility partners utilizing the principles of Adult Learning.
- Maintains personal clinical competency through continuous use of Pruitt University and any other sources needed to maintain and improve skills, including training required by organization.
- Participates in center/agency surveys (Licensure/JCAHO) and any subsequently required reports.
- Attends and participates in continuing educational programs to keep abreast of changes in your field as well as to maintain current license/certification as required.
- Attends and participates in mandatory in-services.
- Honors patients/residents’ rights to fair and equitable treatment, self-determination, individuality, privacy, property and civil rights, including the right to wage complaints.
- Complies with corporate compliance program.
- Reports job-related functions/tasks that involve occupational hazards including exposure to blood and body fluids and others as necessary.
- Follows established safety regulations, to include fire protection and prevention, smoking regulations, infection control, etc.
- Follows established safety procedures when performing tasks and/or working with equipment.
Nursing Degree from an accredited college or university, or is a graduate of an accredited/approved RN program.
MINIMUM EXPERIENCE REQUIRED:
Experience in implementing and maintaining policy-driven practices is highly desirable; history of working with state/federal regulations a plus.
Experience in providing patient, family and/or staff education strongly encouraged.
Recent acute care or LTC experience.
MINIMUM LICENSURE/CERTIFICATION REQUIRED BY LAW:
Current and unrestricted Registered Nurse (RN) licensure in state of practice.
Current CPR (BLS) certification
Within six (6) months of hire successful completion of organizational training programs: IV Certification, Pain Management, Wound Care, Respiratory Care, and CCC Certification.
Within twelve (12) months obtain American Heart Association CPR Instructor certification.
ADDITIONAL QUALIFICATIONS: (Preferred qualifications)
CPR Instructor preferred. Certification by Nationally accredited Nursing Organization highly preferred (i.e. Gerontological Nursing, CRNI, or Certified Nurse Educator).
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As an Equal Employment Opportunity employer, all qualified applicants will receive consideration without regard to race, color, religion, sex, national origin, disability, or veteran status.
For Florida Job Postings Only:
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See All 76 Clinical Project Manager Jobs in Columbia
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Find Clinical Project Manager JobsClinical Project Manager Job Market in Columbia
Who's Hiring
- Prisma Health9

- Lexington Health7

- Circle K5

- State of South Carolina4

- AgFirst Farm Credit Bank3

Top Industries Hiring
- Healthcare & Medical Services21
- Retail5
- Technology & Software5
- Medical Devices3
- Banking & Financial Services3
Clinical Project Manager Jobs in Columbia: Frequently Asked Questions
How do I get a clinical project manager job in Columbia?
Columbia's strongest demand for clinical project managers comes from health systems, contract research organizations, and medical device companies concentrated near the Midlands medical district and the University of South Carolina's research enterprise. Candidates who stand out here typically hold PMP or clinical trial certifications and have direct experience with IRB processes or Phase II-III trial coordination. Networking through SCRA and local PMAC chapter events also gives Columbia applicants a real edge.
Which companies hire clinical project managers in Columbia?
Employers hiring clinical project managers in Columbia right now include Prisma Health, Lexington Health, and Circle K, based on current listings on Migrate Mate as of July 2026. Columbia's hiring mix skews toward academic medical centers, regional health systems, and mid-size CROs that support clinical trial activity tied to the Palmetto Health network and USC's research programs.
Are there remote clinical project manager jobs in Columbia?
Yes, though with important limits: clinical project manager roles that involve on-site trial oversight, site monitoring, or lab coordination are rarely fully remote. About 42% of clinical project manager openings tied to Columbia are remote or hybrid as of July 2026, reflecting that Columbia's research-heavy employers do offer flexibility for documentation, regulatory, and vendor management tasks performed from home.
How can I get a clinical project manager job in Columbia with little or no experience?
The most realistic entry path in Columbia is through clinical research coordinator or project coordinator roles at the USC School of Medicine, Prisma Health, or affiliated CROs, which regularly hire candidates who can demonstrate GCP training and strong data management skills. Volunteering with IRB committees or assisting on grant-funded research at USC gives local candidates direct trial exposure that Columbia employers treat as equivalent to entry-level professional experience.
Which industries hire the most clinical project managers in Columbia?
Most clinical project manager openings in Columbia sit in Healthcare & Medical Services, Retail, and Technology & Software, per current listings on Migrate Mate as of July 2026. Columbia's concentration of academic medical infrastructure, regional health systems, and state government health agencies creates sustained demand across those sectors, particularly for managers who can coordinate multi-site studies and manage regulatory submissions.
Related Jobs in South Carolina
See All 76 Clinical Project Manager Jobs in Columbia
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