Program Director Jobs in South Carolina

Program Director jobs in South Carolina concentrate in healthcare, human services, nonprofit administration, and state government, with demand reaching from entry-level program coordinators stepping into their first director role to seasoned leaders overseeing multi-site operations. Columbia, Charleston, and Greenville anchor most of the hiring, where organizations like Prisma Health, MUSC Health, and the South Carolina Department of Health and Human Services maintain a consistent need for program directors across clinical, community, and administrative divisions. The most in-demand specialties are behavioral health program management, federally funded community services, and hospital operations. Find a role that fits below and apply directly.

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Overview

Open roles28
Top employerSoutheastern College
Top cityColumbia, SC
Cities hiring17
Work type100% On-site
Top industryEducation

Showing 5 of 28+ Program Director jobs

Lifepoint Health
Program Director, Rehabilitation
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Lifepoint Health
Added 1d ago
Program Director, Rehabilitation
Lifepoint Health
Conway, South Carolina
Customer Service
Customer Support
Hospitality & Guest Services
Master's degree
10,000+

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Boys & Girls Clubs of America
21st Century Program Director (Lexington 1)
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Boys & Girls Clubs of America
Added 3d ago
21st Century Program Director (Lexington 1)
Boys & Girls Clubs of America
Lexington, South Carolina
Program Management
Project & Program Management
Project Management
CPR Certification
201-500

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T
Sports and Aquatics Program Director-Aiken
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T
Added 6d ago
Sports and Aquatics Program Director-Aiken
The Family YMCA of Greater Augusta
Graniteville, South Carolina
Account Management
Customer Success
Partnerships & Business Development
$18.27 - $20.9/hr
CPR Certification

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Newberry College
Director for the Center for Teaching and Learning and Honors Program
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Newberry College
Added 1w ago
Director for the Center for Teaching and Learning and Honors Program
Newberry College
Newberry, South Carolina
Corporate Training
Corporate Training & Learning Development
Learning & Development
Master's degree in education
51-200

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Newberry College
Director of the Center for Teaching and Learning and Honors Program
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Newberry College
Added 1w ago
Director of the Center for Teaching and Learning and Honors Program
Newberry College
Newberry, South Carolina
Business Strategy
Product Management
Project Management
Master's degree in education
51-200

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See All 28 Program Director Jobs in South Carolina

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Program Director Jobs by City in South Carolina

Where South Carolina roles are concentrated, by current openings.

Columbia
4 jobs
Greenville
3 jobs
North Charleston
3 jobs
Newberry
2 jobs
Lexington
2 jobs
Aiken
1 job
Greer
1 job
Conway
1 job
Sumter
1 job

Program Director Job Market in South Carolina

A snapshot from current South Carolina openings, updated as new roles post.

Who's Hiring

Southeastern College
Southeastern College4 open roles
Boys & Girls Clubs of America
Boys & Girls Clubs of America4 open roles
Newberry College
Newberry College2 open roles

Top Industries Hiring

  • Education
  • Healthcare & Medical Services
  • Consulting & Professional Services

What South Carolina Employers Look For

The qualifications that appear most often in program director jobs across South Carolina.

  • Bachelor's degree in public health, social work, healthcare administration, or a related field required
  • Minimum five years of program management or supervisory experience in a relevant South Carolina sector
  • Demonstrated ability to manage budgets, grants, or government contracts at the program level
  • Experience navigating South Carolina state agency requirements, reporting standards, or compliance frameworks
  • Strong stakeholder communication skills for working with South Carolina county offices, boards, or funders
  • Proficiency with project management tools and data systems used in healthcare or human services settings

Program Director Jobs in South Carolina: Frequently Asked Questions

How do you become a program director in South Carolina?

Most program director roles in South Carolina require a bachelor's degree in a field relevant to the sector, with a master's degree preferred for healthcare and human services positions. Clinical program director roles within behavioral health or substance use treatment may require licensure through the South Carolina Board of Examiners in Counseling or a comparable state board. Candidates typically build toward the role through program coordinator or manager positions at South Carolina state agencies, hospital systems, or nonprofit providers before moving into director-level responsibility.

Which companies hire program directors in South Carolina?

Employers hiring program directors in South Carolina right now include Southeastern College, Boys & Girls Clubs of America, and Newberry College, based on current listings on Migrate Mate as of September 2026. Anchor institutions like Prisma Health, MUSC Health, and the South Carolina Department of Mental Health generate particularly consistent openings given the scale of their community and clinical programs.

Which South Carolina cities have the most program director jobs?

Columbia, Greenville, and North Charleston account for the largest share of program director openings in South Carolina. Columbia leads because it is the state capital and home to major healthcare systems and state agency headquarters, while Charleston's concentration of academic medicine and federal contractors drives demand there, and Greenville reflects the Upstate's growing hospital networks and expanding nonprofit sector.

Are there remote program director jobs in South Carolina?

Yes, but they are less common than in purely desk-based fields, since many program director roles require on-site oversight of staff, facilities, or client services. About 0% of program director openings tied to South Carolina are remote or hybrid as of September 2026, with most flexibility appearing in grant-funded roles, policy coordination positions, or programs that operate primarily through documentation and reporting rather than direct service delivery.

How can I get hired as a program director in South Carolina with little or no experience?

The most realistic path is securing a program coordinator or case management supervisor role at a South Carolina state agency, community health center, or large nonprofit, then building toward director responsibility from within. Organizations like the South Carolina Department of Social Services and federally qualified health centers across the state regularly hire coordinators who can grow into program leadership. Earning a relevant credential, such as a Certified Nonprofit Professional designation or a master's in public administration, strengthens a candidate's case when competing for director openings ahead of schedule.

Where can I find and apply to program director jobs in South Carolina?

You can find and apply to program director jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Search the available roles, find the ones that match your background and preferred location, and apply directly to the employers posting them.

See All 28 Program Director Jobs in South Carolina

Find roles in South Carolina that match your experience and apply in just a few clicks.

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