Program Director Jobs in South Carolina
Program Director jobs in South Carolina concentrate in healthcare, human services, nonprofit administration, and state government, with demand reaching from entry-level program coordinators stepping into their first director role to seasoned leaders overseeing multi-site operations. Columbia, Charleston, and Greenville anchor most of the hiring, where organizations like Prisma Health, MUSC Health, and the South Carolina Department of Health and Human Services maintain a consistent need for program directors across clinical, community, and administrative divisions. The most in-demand specialties are behavioral health program management, federally funded community services, and hospital operations. Find a role that fits below and apply directly.
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Facility Name: Conway Medical Center
Schedule: Full-Time
Your experience matters
Lifepoint Rehabilitation is part of Lifepoint Health, a diversified healthcare delivery network with facilities coast to coast. We are driven by a profound commitment to prioritize your well-being so you can provide exceptional care to others. As a Program Director joining our team, you’re embracing a vital mission dedicated to making communities healthier ®. Join us on this meaningful journey where your skills, compassion and dedication will make a remarkable difference in the lives of those we serve.
How you’ll contribute
A Program Director who excels in this role:
- Oversee the operations of the inpatient rehabilitation program including clinical, financial, and administrative performance.
- Collaborate with interdisciplinary teams to ensure high-quality patient care and compliance with treatment standards.
- Develop and manage departmental budgets, goals, and strategic plans.
- Maintain compliance with federal, state, and accrediting agencies.
- Supervise and develop staff; provide ongoing training and support.
- Analyze performance metrics and implement quality improvement initiatives.
- Represent the rehab program in internal and external meetings.
- Perform other duties as assigned.
Why join us
We believe that investing in our employees is the first step to providing excellent patient care. In addition to your base compensation, this position also offers:
- Comprehensive Benefits: Multiple levels of medical, dental and vision coverage for full-time and part-time employees.
- Financial Protection & PTO: Life, accident, critical illness, hospital indemnity insurance, short- and long-term disability, paid family leave and paid time off.
- Financial & Career Growth: Higher education and certification tuition assistance, loan assistance and 401(k) retirement package and company match.
- Employee Well-being: Mental, physical, and financial wellness programs (free gym memberships, virtual care appointments, mental health services and discount programs).
- Professional Development: Ongoing learning and career advancement opportunities.
What we’re looking for
- Education: Bachelor’s degree in clinical discipline (e.g. RN, PT, OT, SLP, or SW) or healthcare management required; Master’s preferred.
- Experience: Minimum of 3 years in rehab leadership or administration.
- License: Valid clinical license as applicable by state.
EEOC Statement
“Lifepoint Rehabilitation is an Equal Opportunity Employer. Lifepoint Rehabilitation is committed to Equal Employment Opportunity for all applicants and employees and complies with all applicable laws prohibiting discrimination and harassment in employment.”
We employ and provide care to people from all walks of life. We are committed to promoting healing, providing hope, preserving dignity and producing value with an inclusive workforce in which diversity is leveraged, respected, and reflective of the patients, family members, customers and team members we serve.Lifepoint Health is a leader in community-based care and driven by a mission of Making Communities Healthier. Our diversified healthcare delivery network spans 29 states and includes 63 community hospital campuses, 32 rehabilitation and behavioral health hospitals, and more than 170 additional sites of care across the healthcare continuum, such as acute rehabilitation units, outpatient centers and post-acute care facilities. We believe that success is achieved through talented people. We want to create places where employees want to work, with opportunities to pursue meaningful and satisfying careers that truly make a difference in communities across the country.See All 28 Program Director Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Program Director JobsProgram Director Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Program Director Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Education
- Healthcare & Medical Services
- Consulting & Professional Services
What South Carolina Employers Look For
The qualifications that appear most often in program director jobs across South Carolina.
- Bachelor's degree in public health, social work, healthcare administration, or a related field required
- Minimum five years of program management or supervisory experience in a relevant South Carolina sector
- Demonstrated ability to manage budgets, grants, or government contracts at the program level
- Experience navigating South Carolina state agency requirements, reporting standards, or compliance frameworks
- Strong stakeholder communication skills for working with South Carolina county offices, boards, or funders
- Proficiency with project management tools and data systems used in healthcare or human services settings
Program Director Jobs in South Carolina: Frequently Asked Questions
How do you become a program director in South Carolina?
Most program director roles in South Carolina require a bachelor's degree in a field relevant to the sector, with a master's degree preferred for healthcare and human services positions. Clinical program director roles within behavioral health or substance use treatment may require licensure through the South Carolina Board of Examiners in Counseling or a comparable state board. Candidates typically build toward the role through program coordinator or manager positions at South Carolina state agencies, hospital systems, or nonprofit providers before moving into director-level responsibility.
Which companies hire program directors in South Carolina?
Employers hiring program directors in South Carolina right now include Southeastern College, Boys & Girls Clubs of America, and Newberry College, based on current listings on Migrate Mate as of September 2026. Anchor institutions like Prisma Health, MUSC Health, and the South Carolina Department of Mental Health generate particularly consistent openings given the scale of their community and clinical programs.
Which South Carolina cities have the most program director jobs?
Columbia, Greenville, and North Charleston account for the largest share of program director openings in South Carolina. Columbia leads because it is the state capital and home to major healthcare systems and state agency headquarters, while Charleston's concentration of academic medicine and federal contractors drives demand there, and Greenville reflects the Upstate's growing hospital networks and expanding nonprofit sector.
Are there remote program director jobs in South Carolina?
Yes, but they are less common than in purely desk-based fields, since many program director roles require on-site oversight of staff, facilities, or client services. About 0% of program director openings tied to South Carolina are remote or hybrid as of September 2026, with most flexibility appearing in grant-funded roles, policy coordination positions, or programs that operate primarily through documentation and reporting rather than direct service delivery.
How can I get hired as a program director in South Carolina with little or no experience?
The most realistic path is securing a program coordinator or case management supervisor role at a South Carolina state agency, community health center, or large nonprofit, then building toward director responsibility from within. Organizations like the South Carolina Department of Social Services and federally qualified health centers across the state regularly hire coordinators who can grow into program leadership. Earning a relevant credential, such as a Certified Nonprofit Professional designation or a master's in public administration, strengthens a candidate's case when competing for director openings ahead of schedule.
Where can I find and apply to program director jobs in South Carolina?
You can find and apply to program director jobs in South Carolina on Migrate Mate, which lists current openings from employers across the state. Search the available roles, find the ones that match your background and preferred location, and apply directly to the employers posting them.
See All 28 Program Director Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find Program Director Jobs