Clinical Research Director Jobs in Illinois
Clinical Research Director jobs in Illinois are open across North Chicago, Mettawa, and Chicago and other Illinois metros, with employers like AbbVie, Abbvie Bioresearch Center, and Nimble Therapeutics hiring at every experience level. Find a role that fits below and apply directly.
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Total Rewards:
"Your life - our Mission"
OSF HealthCare is dedicated to provide Mission Partners with a comprehensive and market-competitive total rewards package that includes benefits, compensation, recognition and well-being offerings that focus on the whole person and engage with their current stage of life and career. Click here to learn more about benefits and the total rewards at OSF.
Expected pay for this position is $62.64 - $83.00/hour. Actual pay will be determined by experience, skills and internal equity. This is a Salaried position.
Position Summary:
The Director, Research Operations & Standardization provides ministry-level leadership for operational excellence, process standardization, and workforce development across the OSF HealthCare research enterprise. This role establishes standardized operational frameworks, performance expectations, and training infrastructure to ensure consistent, high-quality research conduct across all OSF facilities. Operating within a hybrid model, the director partners with site-based research leaders to drive alignment with ministry standards, improve performance, and strengthen operational consistency across the system. This role collaborates closely with Research Compliance and Research Financial & Systems leaders to ensure research operations are efficient, compliant, and sustainable.
REQUIRED QUALIFICATIONS:
Education: Bachelor’s degree in healthcare administration, public health, nursing, biological/life sciences, or related field.
Experience:
- 7 years progressive experience in clinical research operations within a healthcare or academic medical center environment.
- 3 years in formal leadership role overseeing research coordinators, managers, or operational teams.
- Demonstrated experience standardizing multi-site operational workflows.
Licensure/ Certification: Current Research Certification such as: SOCRA (Society of Clinical Research Administration), ACRP (Association of Clinical Research Professionals), HCCA (Health Care Compliance Association), etc. – expected within 1 year of hire in the job.
Other Skills/ Knowledge:
- Excellent interpersonal and communication skills.
- Solid computer skills, including proficiency with Microsoft software.
- Strong analytical and problem-solving skills, with the ability to be detail oriented.
- Strong understanding of clinical trial activation processes, study lifecycle management, and enrollment operations.
- Demonstrated ability to develop and track operational KPIs and performance dashboards.
- Strong project management and change management capabilities.
- Ability to influence and drive alignment within a matrixed organizational structure.
- Excellent communication and leadership skills.
- Familiarity with research systems such as, but not limited to, the following: Epic research functionality, CTMS (Clinical Trial Management System), REDCap (Research Electronic Data Capture), iRIS (Integrate Research Information System)/Cayuse.
PREFERRED QUALIFICATIONS:
Education: Master’s degree in healthcare administration, public health, business administration, or related field.
Experience:
- Experience operating within a hybrid centralized research model.
- Experience with change management (including conflict management).
- Experience supporting oncology, industry-sponsored, or FDA-regulated research.
Licensure/ Certification:
- Lean or Six Sigma certification.
- Project Management Professional (PMP).
- Research Compliance Related Certification (e.g. Certified in Healthcare Research Compliance – CHRC).
Other Skills/ Knowledge:
- Knowledge of clinical research operations, study data management, and electronic data capture (EDC) systems.
- General understanding of medical terminology. Clinical Trial Management Systems (CTMS), REDcap, Participant Payment Solution, Cosmos, and/or other research software systems.
OSF HealthCare is an Equal Opportunity Employer.
See All 14 Clinical Research Director Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
Find JobsClinical Research Director Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Clinical Research Director Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
Who's Hiring
- AbbVie7

- Abbvie Bioresearch Center3

- Nimble Therapeutics2

- OSF HealthCare1

- Tempus AI1

Top Industries Hiring
- Biotechnology & Pharmaceuticals13
- Healthcare & Medical Services3
- Medical Devices1
What Illinois Employers Look For
The qualifications that appear most often in clinical research director jobs across Illinois.
- Bachelor's or advanced degree in life sciences, nursing, or a clinical field
- Minimum of eight to ten years of clinical research experience including supervisory roles
- Demonstrated experience overseeing Phase II through Phase IV clinical trials
- Current Good Clinical Practice certification aligned with ICH-GCP guidelines
- Proficiency with clinical trial management systems such as Medidata Rave or Veeva Vault
- Experience preparing and submitting regulatory documents to the FDA or equivalent agencies
Clinical Research Director Jobs in Illinois: Frequently Asked Questions
How many clinical research director jobs are there in Illinois?
There are 14+ clinical research director openings in Illinois on Migrate Mate as of June 2026, with the most roles in North Chicago, Mettawa, and Chicago. New positions post regularly as employers across Illinois hire.
Which Illinois cities have the most clinical research director jobs?
North Chicago, Mettawa, and Chicago have the most clinical research director openings in Illinois right now, with additional roles spread across smaller metros statewide.
Which companies hire clinical research directors in Illinois?
Employers hiring clinical research directors in Illinois include AbbVie, Abbvie Bioresearch Center, and Nimble Therapeutics, based on current listings on Migrate Mate as of June 2026.
Are there remote clinical research director jobs in Illinois?
Yes. About 14% of clinical research director openings tied to Illinois are remote or hybrid as of June 2026. The rest are on-site roles based in Illinois metros.
How do I apply for clinical research director jobs in Illinois?
You can apply to clinical research director jobs in Illinois directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Illinois location, then apply to each one that fits.
See All 14 Clinical Research Director Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
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