Physician Assistant Jobs in Illinois
Physician assistant jobs in Illinois are consistently in demand, with a strong concentration in primary care, urgent care, emergency medicine, and surgical specialties across health systems ranging from large academic medical centers to rural federally qualified health centers. Chicago, Peoria, and Rockford account for the largest share of openings, and established employers such as Northwestern Medicine, Advocate Health Care, and OSF HealthCare maintain ongoing hiring at every level from new graduate through senior and supervising PA roles. Demand is especially high in orthopedics, hospital medicine, and oncology, reflecting the growth of specialized outpatient and inpatient programs throughout the state. Find a role that fits below and apply directly.
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HSHS Medical Group is seeking a Board-Certified/Board-Eligible Nurse Practitioner or Physician Assistant to join our growing Gastroenterology team in O’Fallon, Illinois. This role primarily focuses on outpatient clinic responsibilities with occasional hospital rounding as needed.
You’ll be part of a well-established and expanding practice within the Hospital Sisters Health System, working closely with a multidisciplinary team to deliver high-quality patient care.
Practice Highlights:
- Well established, growing practice.
- No holidays or weekends
- No required call
- EPIC EMR
- Clinics are within the hospitals, providing access to all imaging, labs, scans, etc. needed.
- Ample training time provided with GI team.
Position Requirements:
- Unrestricted Illinois license and DEA prior to start
- Board Certified
- 2+ years of provider work experience is strongly preferred.
- Experience in GI is preferred, but experience in other specialties will also be
Compensation & Benefits Package:
- Base Salary: $128,153 With Bonus Earning Potential
- Paid time off with holidays accrued bi-weekly
- CME reimbursement + days available per fiscal year
- Opportunities to earn productivity and patient outcome/patient satisfaction
- Sign on bonus and relocation assistance both available
Core Function: Provider
Education Qualifications
- Master’s degree in Nursing is required.
- Bachelor’s Degree in Nursing PLUS 5 years relevant experience may be considered in lieu of degree.
- Doctoral degree in Nursing is preferred.
- Experience in management of patients across the care continuum preferred.
- Licensed in the state of practice as Advanced Practice Registered Nurse is required.
- Wisconsin Department of Safety and Professional Services (WDSPS) or
- Illinois Department of Financial and Professional Regulation (IDFPR)
- Basic Life Support (BLS) certification is required.
- Board certification from the National Certification Corporation is preferred.
- Controlled Substance license in state of practice is preferred.
- Federal DEA license is preferred.
- Neonatal Resuscitation Program (NRP) certification is preferred.
Throughout communities in Illinois and Wisconsin, 13 hospitals, numerous community-based health centers and clinics, our 13,000+ colleagues have built a culture based on our solid core values of respect, care, competence, and joy. These are the ideals we believe in, work by, and live each day.
Built upon more than 145 years of service to the communities we serve, we now look to the future and our place in it as a healthcare system that strives to continually improve processes, procedures, and outcomes with the latest and most advanced technologies and treatments.
Regardless of how far our passion for excellence carries us, our focus will always remain on the most important person in our entire organization: The patient.
HSHS requires COVID-19 vaccines or an approved medical or religious exemption for all colleagues.
HSHS and affiliates is an Equal Opportunity Employer (EOE).
HSHS is proud to be an equal opportunity workplace dedicated to pursuing and hiring a diverse workforce.
Benefits: HSHS provides a benefits package designed to support the overall well-being of our colleagues including their physical, emotional, financial, spiritual, and work health. Colleagues budgeted to work at least 32 hours per pay period are eligible for HSHS benefits.
- Comprehensive and affordable health coverage includes medical, prescription, dental and vision coverage for full-time and part-time colleagues.
- Retirement benefits including HSHS contributions.
- Education Assistance benefits include up to $5,250 of educational assistance each calendar year and tuition discounts to select colleges with no waiting period
- Adoption Assistance provides financial support up to $7,500 for colleagues growing their families through adoption to reimburse application and legal fees, transportation, and more!
- Other benefits include: Wellness program with incentives, employer-paid life insurance and short-term and long-term disability coverage, flexible spending accounts, employee assistance program, ID theft coverage, colleague rewards and recognition program, discount program, and more!
A successful candidate's actual pay rate will be based on several factors including relevant experience, skills, training, certifications and education.
Notice Regarding Potential Use of Artificial Intelligence in the Hiring Process
Hospital Sisters may use automated tools, including artificial intelligence or machine-learning technologies, to assist with certain administrative aspects of the recruitment process. These tools may help our recruiting team organize applications, search for resumes, identify qualifications reflected in application materials, and facilitate communications or scheduling with applicants.
Information used by these tools may include materials you provide during the application process, such as your resume, work history, education, qualifications, and responses to application questions.
These tools are used only to support our recruiting process. Hiring decisions are made by HSHS personnel, and automated tools do not make employment decisions on behalf of HSHS.
Applicants who have questions about this notice or who require a reasonable accommodation or alternative evaluation method may contact HSHS Human Resources at Contact@hshs.org
See All 96 Physician Assistant Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
Find Physician Assistant JobsPhysician Assistant Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Physician Assistant Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
Who's Hiring
- Northwestern Medicine26

- Memorial Health9

- Advocate Aurora Health9

- 77 Consultants47
- Duly Health and Care4

Top Industries Hiring
- Insurance
- Healthcare & Medical Services
What Illinois Employers Look For
The qualifications that appear most often in physician assistant jobs across Illinois.
- Active Illinois Physician Assistant license issued by the Illinois Department of Financial and Professional Regulation
- Graduation from an ARC-PA accredited physician assistant program with a master's degree
- Current NCCPA certification or board eligibility for new graduates
- Current BLS certification, with ACLS required for emergency, critical care, or hospital-based roles
- Experience or clinical rotations in the relevant specialty such as orthopedics, urgent care, or surgical subspecialties
- Strong electronic medical record proficiency, with Epic experience preferred by most major Illinois health systems
Physician Assistant Jobs in Illinois: Frequently Asked Questions
How do you become a physician assistant in Illinois?
To practice as a physician assistant in Illinois, you must hold an active license issued by the Illinois Department of Financial and Professional Regulation. Licensure requires graduation from an ARC-PA accredited master's-level PA program and passing the PANCE administered by the National Commission on Certification of Physician Assistants. Once licensed, you maintain active status through continuing medical education and NCCPA recertification every ten years, with a knowledge assessment required every six years.
How much do physician assistants make in Illinois?
Physician assistants in Illinois earn a median of about $131,950 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $105,160 for the lowest 10% to over $162,330 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire physician assistants in Illinois?
Employers hiring physician assistants in Illinois right now include Northwestern Medicine, Memorial Health, and Advocate Aurora Health, based on current listings on Migrate Mate as of October 2026. Illinois's large integrated health systems and growing multispecialty groups consistently post the highest volume of PA openings across hospital-based, outpatient clinic, and surgical assistant roles throughout the state.
Which Illinois cities have the most physician assistant jobs?
Chicago, Decatur, and Huntley have the most physician assistant openings in Illinois. Chicago drives the largest share given its concentration of academic medical centers, Level I trauma centers, and large multispecialty groups, while Peoria and Rockford reflect strong regional health systems including OSF HealthCare and Mercyhealth anchoring suburban and downstate hiring.
Are there remote physician assistant jobs in Illinois?
Yes, but they're rare. Physician assistant work is almost entirely hands-on and clinical, so most positions require on-site patient contact. About 12% of physician assistant openings tied to Illinois are remote or hybrid as of October 2026, and those roles are typically limited to telehealth triage, utilization review, or insurance prior-authorization positions that do not involve direct in-person care.
How can I get hired as a physician assistant in Illinois with little or no experience?
The most realistic entry path for new graduates is applying to postgraduate PA residency or fellowship programs run by Illinois health systems, including those at Northwestern Medicine and Advocate Health Care, which offer structured training in specialties such as emergency medicine, surgery, and internal medicine. Many Illinois employers also hire new graduates directly into primary care and urgent care roles where onboarding support is built into the position. Candidates strengthen their applications by completing relevant clinical rotations at Illinois institutions, holding an active Illinois PA license before applying, and targeting community health centers that receive federal support and often prioritize new-grad hiring.
Where can I find and apply to physician assistant jobs in Illinois?
You can find and apply to physician assistant jobs in Illinois on Migrate Mate, which lists current Illinois openings from health systems, multispecialty groups, and outpatient clinics across the state. Find the roles that fit your specialty, experience level, and preferred location, then apply directly to each employer through the listing.
See All 96 Physician Assistant Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
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