Physician Assistant Jobs in Chicago, IL

Physician assistant jobs in Chicago are concentrated in the Medical District, Streeterville, and Evanston, driven by major academic medical centers, large hospital networks, and multispecialty clinics across primary care, surgery, and urgent care. Employers actively hiring include Northwestern Medicine, Cook County Health & Hospitals System, and Optum. Find a role that fits below and apply directly.

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Overview

Open roles96
Top employerNorthwestern Medicine
Work type80% On-site
Top credentialBLS Certification
Companies hiring11

Showing 5 of 96+ Physician Assistant jobs

Physician Assistant or Nurse Practitioner - Emergency Medicine Casual Rotating
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Added 1d ago
Physician Assistant or Nurse Practitioner - Emergency Medicine Casual Rotating
Northwestern Medicine
Chicago, Illinois
Healthcare Administration
Nursing
Patient Services & Wellbeing
$63 - $82.28/hr
BLS Certification
10,000+

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Acute Care Nurse Practitioner or Physician Assistant - General Cardiology and Advanced Heart Failure, Full-time, Days
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Added 4d ago
Acute Care Nurse Practitioner or Physician Assistant - General Cardiology and Advanced Heart Failure, Full-time, Days
Northwestern Medicine
Chicago, Illinois
Allied Health
Clinical Support
Healthcare Administration
$61 - $79.67/hr
BLS Certification
10,000+

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Physician Assistant I - Cermak
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Added 4d ago
Physician Assistant I - Cermak
Cook County Health & Hospitals System
Chicago, Illinois
Clinical Support
Healthcare Administration
Medical Specialists
$63.31 - $71.26/hr
BLS Certification

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Physician Assistant I - Surgery
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Added 5d ago
Physician Assistant I - Surgery
Cook County Health & Hospitals System
Chicago, Illinois
Clinical Support
Healthcare Administration
Medical Specialists
$63.31 - $71.26/hr
BLS Certification

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Personal Assistant / House Manager: Join the Friday PA Network
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Added 1w ago
Personal Assistant / House Manager: Join the Friday PA Network
Friday Personal Assistants
Chicago, Illinois
Healthcare Administration
Patient Services & Wellbeing
Physical Therapy

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See All 96 Physician Assistant Jobs in Chicago

Find roles in Chicago that match your experience and apply in just a few clicks.

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Physician Assistant Job Market in Chicago

Who's Hiring

  • Northwestern Medicine48
  • Cook County Health & Hospitals System12
  • Optum4
  • Concentra4
  • Aayu Clinics4

Top Industries Hiring

  • Insurance

Physician Assistant Jobs in Chicago: Frequently Asked Questions

How do I get a physician assistant job in Chicago?

Target the Medical District near Illinois Medical Center, Streeterville's dense cluster of academic hospitals, and the North Shore suburban health systems that pull heavily from the Chicago market. Large health systems, federally qualified health centers serving underserved neighborhoods, and multispecialty groups in the Loop all hire regularly. Candidates with surgical subspecialty experience or bilingual Spanish skills have a clear edge given Chicago's patient population.

Which companies hire physician assistants in Chicago?

Chicago physician assistant roles are posted by Northwestern Medicine, Cook County Health & Hospitals System, and Optum and others right now, based on current listings on Migrate Mate as of October 2026. The mix reflects Chicago's employer landscape: large academic health systems, regional hospital networks, and independent multispecialty practices concentrated on the North Side and in the western suburbs.

Are there remote physician assistant jobs in Chicago?

Yes, though options are limited, since physician assistant work is largely hands-on and clinic-based. About 20% of physician assistant openings tied to Chicago are remote or hybrid as of October 2026, primarily covering roles in utilization review, telehealth triage, and chronic disease management programs offered by larger Chicago-area health systems.

How can I get a physician assistant job in Chicago with little or no experience?

The most realistic entry path in Chicago is through Federally Qualified Health Centers and community health organizations serving neighborhoods like Pilsen, Englewood, and Austin, where entry-level PAs are actively recruited. Hospital systems affiliated with Rush, Loyola, and Advocate Health also run new-grad cohort programs. Rotations or clinical hours completed at Chicago institutions strengthen local recognition considerably.

Which industries hire the most physician assistants in Chicago?

Most physician assistant openings in Chicago sit in Insurance, per current listings on Migrate Mate as of October 2026. Chicago's concentration of Level I trauma centers, large academic medical systems, and growing urgent care networks drives consistent demand across those sectors throughout the year.

See All 96 Physician Assistant Jobs in Chicago

Find roles in Chicago that match your experience and apply in just a few clicks.

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