Senior Level Clinical Research Manager Jobs
Senior level clinical research manager jobs place experienced professionals in charge of trial strategy, regulatory oversight, and the cross-functional teams that deliver study outcomes. Hiring is concentrated across Education, Healthcare & Medical Services, and Biotechnology & Pharmaceuticals, with a mix of on-site, hybrid, and remote roles available from employers like Jobot, Colgate-Palmolive, and Cambridge Pharma Consulting hiring at this level now.
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The University of Alabama at Birmingham (UAB), Family & Community Medicine Chair Office, is seeking a Manager-Clinical Research Administration.
The Clinical Research Administration Manager will play a pivotal role in overseeing all aspects of clinical trial operations within the Department of Family and Community Medicine at UAB. This position is responsible for managing a team of clinical coordinators, ensuring compliance with regulatory requirements, and fostering collaboration with internal and external research sites. The ideal candidate will demonstrate strong leadership, organizational, and communication skills, with a proven track record in clinical research management.
General Responsibilities
To act as a subject matter expert (SME) for faculty and staff regarding administrative duties for industry and sponsored clinical research.
To serve as a referral resource for the clinical research community at UAB.
To manage and maintain the study s compliance with institutional requirements.
To manage division-wide training in ethical conduct of research.
To manage, assess and determine solutions for operational shortcomings of protocols.
To provide human resources oversight for subordinate personnel.
Key Duties & Responsibilities
Manages and supervises clinical research coordinators and research staff, including all applicable human resource functions, across multiple ongoing and upcoming clinical trials.
Prepares, submits, and maintains regulatory documentation, including IRB submissions, amendments, and continuing reviews, while supporting broader regulatory compliance activities as needed.
Leads and coordinates study activation, site initiation, ongoing management, and study closeout activities across multiple clinical research protocols.
Monitors study progress and staff activities to ensure adherence to study protocols, timelines, budgets, and all clinical and regulatory requirements.
Develops protocol-specific systems and study documentation, including process flows, training materials, CRFs, and other operational tools.
Prepares and manages study budgets, and collaborates with investigators and sponsors on financial planning and execution.
Provides training, mentorship, and professional development for research staff, including assigning responsibilities, reviewing work, and identifying process improvements.
Coordinates communication with internal teams, investigators, sponsors, and external research sites to ensure efficient trial operations and data integrity.
Develops and implements recruitment and retention strategies to support successful study enrollment and completion.
Ensures compliance with all applicable federal, state, and institutional regulations and guidelines (e.g., FDA, IRB, GCP).
Collaborates with investigators, sponsors, and other stakeholders to support successful trial execution.
Performs other duties as assigned.
Annual Salary Range: $77,640 - $126,170
Bachelor's degree in a related field and eight (8) years of related experience required. Work experience may NOT substitute for education requirement. Certified Clinical Research Coordinator (CCRC) or Certified Clinical Research Professional (CCRP) certification strongly preferred.
UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.
The University of Alabama at Birmingham (UAB), Family & Community Medicine Chair Office, is seeking a Manager-Clinical Research Administration.
The Clinical Research Administration Manager will play a pivotal role in overseeing all aspects of clinical trial operations within the Department of Family and Community Medicine at UAB. This position is responsible for managing a team of clinical coordinators, ensuring compliance with regulatory requirements, and fostering collaboration with internal and external research sites. The ideal candidate will demonstrate strong leadership, organizational, and communication skills, with a proven track record in clinical research management.
General Responsibilities
To act as a subject matter expert (SME) for faculty and staff regarding administrative duties for industry and sponsored clinical research.
To serve as a referral resource for the clinical research community at UAB.
To manage and maintain the study s compliance with institutional requirements.
To manage division-wide training in ethical conduct of research.
To manage, assess and determine solutions for operational shortcomings of protocols.
To provide human resources oversight for subordinate personnel.
Key Duties & Responsibilities
Manages and supervises clinical research coordinators and research staff, including all applicable human resource functions, across multiple ongoing and upcoming clinical trials.
Prepares, submits, and maintains regulatory documentation, including IRB submissions, amendments, and continuing reviews, while supporting broader regulatory compliance activities as needed.
Leads and coordinates study activation, site initiation, ongoing management, and study closeout activities across multiple clinical research protocols.
Monitors study progress and staff activities to ensure adherence to study protocols, timelines, budgets, and all clinical and regulatory requirements.
Develops protocol-specific systems and study documentation, including process flows, training materials, CRFs, and other operational tools.
Prepares and manages study budgets, and collaborates with investigators and sponsors on financial planning and execution.
Provides training, mentorship, and professional development for research staff, including assigning responsibilities, reviewing work, and identifying process improvements.
Coordinates communication with internal teams, investigators, sponsors, and external research sites to ensure efficient trial operations and data integrity.
Develops and implements recruitment and retention strategies to support successful study enrollment and completion.
Ensures compliance with all applicable federal, state, and institutional regulations and guidelines (e.g., FDA, IRB, GCP).
Collaborates with investigators, sponsors, and other stakeholders to support successful trial execution.
Performs other duties as assigned.
Annual Salary Range: $77,640 - $126,170
Bachelor's degree in a related field and eight (8) years of related experience required. Work experience may NOT substitute for education requirement. Certified Clinical Research Coordinator (CCRC) or Certified Clinical Research Professional (CCRP) certification strongly preferred.
UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.
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Senior Level Clinical Research Manager Jobs: Frequently Asked Questions
How do I get a senior level clinical research manager job?
Employers at this level look for candidates who have owned full trial lifecycles, managed cross-functional teams, and navigated regulatory submissions independently. A strong candidate demonstrates depth in ICH-GCP compliance, experience mentoring junior staff, and a history of delivering complex studies on time. Tailoring your application to show leadership outcomes, not just task completion, gives you a real edge.
Which companies hire senior level clinical research managers?
Companies hiring senior level clinical research managers right now include Jobot, Colgate-Palmolive, and Cambridge Pharma Consulting, based on current listings on Migrate Mate as of August 2026. Hiring at this level comes from a mix of large pharmaceutical manufacturers, contract research organizations, and biotech firms running late-phase or multi-site trials.
Are there remote senior level clinical research manager jobs?
Yes, though availability varies by employer and therapeutic area. About 40% of senior level clinical research manager openings are remote or hybrid as of August 2026, reflecting how many organizations have adapted oversight and monitoring workflows to distributed teams. On-site roles tend to be tied to sponsors with active investigator sites or internal lab operations.
What makes a clinical research manager role senior level?
Senior level roles are defined by ownership rather than execution. You are setting trial strategy, accountable for regulatory and protocol decisions, managing the performance of clinical teams, and serving as the primary point of escalation for site or vendor issues. These positions also carry mentoring responsibility, developing junior managers and coordinators as part of the day-to-day scope.
Which industries hire the most senior level clinical research managers?
Senior Level clinical research manager roles concentrate in Education, Healthcare & Medical Services, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of August 2026. These sectors drive hiring at this level because they run the largest volume of regulated clinical programs, require experienced leadership to manage investigator networks, and face the most demanding submission timelines.