Arrowhead Pharmaceuticals Visa Sponsorship Jobs USA
Arrowhead Pharmaceuticals is a clinical-stage biotech focused on RNA interference therapeutics, offering Green Card sponsorship pathways for skilled researchers and scientists. While not a high-volume sponsor, the company does support permanent residency for select specialized roles, making it a meaningful target for candidates with the right scientific background.
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Get Access To All JobsINTRODUCTION
Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
THE POSITION
The Director of IT Infrastructure is a leadership role responsible for the strategy, design, implementation, and ongoing operations of the company's enterprise IT infrastructure. This leader will oversee a geographically distributed environment spanning on-premises and public cloud platforms (Microsoft Azure and Amazon Web Services). The Director will lead a team of infrastructure staff to support business needs, drive modernization initiatives, and ensure the reliability and scalability of all infrastructure services in alignment with pharmaceutical industry standards.
This role is based onsite 5 days a week from one of Arrowhead's office locations.
Responsibilities
- Define and execute a multi-year IT infrastructure roadmap aligned with corporate growth objectives and digital transformation priorities.
- Lead, mentor, and develop a high-performing infrastructure team across multiple sites.
- Partner with the IS leadership and business stakeholders to align infrastructure investments with organizational priorities and compliance requirements.
- Establish and manage infrastructure budgets, vendor contracts, and technology refresh cycles.
- Develop and communicate infrastructure KPIs, SLAs, and operational metrics to IS leadership.
- Oversee the design, deployment, and lifecycle management of virtualization infrastructure across all company locations.
- Manage a Microsoft Active Directory environment.
- Drive hybrid cloud strategy and operations across Azure and AWS, optimizing workload placement, cost, and performance.
- Ensure high availability, disaster recovery, and business continuity capabilities for all critical infrastructure components.
- Oversee network infrastructure including LAN/WAN and SD-WAN connectivity across all company sites and cloud tenants.
- Oversee server patching and configuration management standards across the enterprise.
- Lead capacity planning and performance monitoring to ensure infrastructure scalability in support of business growth.
- Ensure all infrastructure platforms and processes comply with regulatory requirements as applicable.
- Support internal and external audits by providing documentation, evidence, and technical guidance related to infrastructure controls.
- Maintain and test disaster recovery and incident response plans in partnership with IS and business teams.
- Lead infrastructure-related projects from inception through delivery, including consolidations, cloud migrations, and site expansions.
- Manage relationships with key technology vendors and MSPs, negotiating contracts and ensuring service delivery accountability.
- Evaluate and recommend emerging technologies that drive operational efficiency and cost reduction.
REQUIREMENTS
- Bachelor's degree in Computer Science, Information Systems, Information Technology, or a related field.
- 10+ years of progressive IT infrastructure experience, with at least 4 years in a senior leadership or director-level role.
- Deep hands-on expertise with virtualization platforms (VMware, Nutanix, Hyper-V).
- Demonstrated experience managing Microsoft Active Directory.
- Strong working knowledge of AWS and Azure — architecture, operations, cost management, and security.
- Experience managing multi-site enterprise IT environments in a regulated industry.
- Proven track record of building, leading, and developing high-performing infrastructure teams.
- Strong understanding of network architecture, security principles, and ITIL-based service management frameworks.
- Experience with infrastructure compliance frameworks relevant to pharma/biotech (GxP, SOX, HIPAA).
PREFERRED
- Current or previous industry certifications such as VMware VCP/VCAP, Azure Administrator/Architect, AWS Solutions Architect, or ITIL v4.
- Experience with infrastructure-as-code tools such as Terraform, Ansible, or Bicep.
- Experience supporting laboratory and manufacturing IT environments (OT/IT convergence) within a pharmaceutical or life sciences setting.
- Strategic thinking and the ability to translate business needs into scalable infrastructure solutions.
- Strong communication skills - able to present complex technical topics clearly to non-technical audiences.
- Exceptional organizational and prioritization skills in a fast-paced, regulated environment.
- Collaborative leadership style with a strong emphasis on team development and cross-functional partnership.
- Data-driven decision-making and a continuous improvement mindset.
Arrowhead provides competitive salaries and an excellent benefit package.
Candidates must have current, valid authorization to work in the country where this role is located.
California Applicant Privacy Policy
INTRODUCTION
Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
THE POSITION
The Director of IT Infrastructure is a leadership role responsible for the strategy, design, implementation, and ongoing operations of the company's enterprise IT infrastructure. This leader will oversee a geographically distributed environment spanning on-premises and public cloud platforms (Microsoft Azure and Amazon Web Services). The Director will lead a team of infrastructure staff to support business needs, drive modernization initiatives, and ensure the reliability and scalability of all infrastructure services in alignment with pharmaceutical industry standards.
This role is based onsite 5 days a week from one of Arrowhead's office locations.
Responsibilities
- Define and execute a multi-year IT infrastructure roadmap aligned with corporate growth objectives and digital transformation priorities.
- Lead, mentor, and develop a high-performing infrastructure team across multiple sites.
- Partner with the IS leadership and business stakeholders to align infrastructure investments with organizational priorities and compliance requirements.
- Establish and manage infrastructure budgets, vendor contracts, and technology refresh cycles.
- Develop and communicate infrastructure KPIs, SLAs, and operational metrics to IS leadership.
- Oversee the design, deployment, and lifecycle management of virtualization infrastructure across all company locations.
- Manage a Microsoft Active Directory environment.
- Drive hybrid cloud strategy and operations across Azure and AWS, optimizing workload placement, cost, and performance.
- Ensure high availability, disaster recovery, and business continuity capabilities for all critical infrastructure components.
- Oversee network infrastructure including LAN/WAN and SD-WAN connectivity across all company sites and cloud tenants.
- Oversee server patching and configuration management standards across the enterprise.
- Lead capacity planning and performance monitoring to ensure infrastructure scalability in support of business growth.
- Ensure all infrastructure platforms and processes comply with regulatory requirements as applicable.
- Support internal and external audits by providing documentation, evidence, and technical guidance related to infrastructure controls.
- Maintain and test disaster recovery and incident response plans in partnership with IS and business teams.
- Lead infrastructure-related projects from inception through delivery, including consolidations, cloud migrations, and site expansions.
- Manage relationships with key technology vendors and MSPs, negotiating contracts and ensuring service delivery accountability.
- Evaluate and recommend emerging technologies that drive operational efficiency and cost reduction.
REQUIREMENTS
- Bachelor's degree in Computer Science, Information Systems, Information Technology, or a related field.
- 10+ years of progressive IT infrastructure experience, with at least 4 years in a senior leadership or director-level role.
- Deep hands-on expertise with virtualization platforms (VMware, Nutanix, Hyper-V).
- Demonstrated experience managing Microsoft Active Directory.
- Strong working knowledge of AWS and Azure — architecture, operations, cost management, and security.
- Experience managing multi-site enterprise IT environments in a regulated industry.
- Proven track record of building, leading, and developing high-performing infrastructure teams.
- Strong understanding of network architecture, security principles, and ITIL-based service management frameworks.
- Experience with infrastructure compliance frameworks relevant to pharma/biotech (GxP, SOX, HIPAA).
PREFERRED
- Current or previous industry certifications such as VMware VCP/VCAP, Azure Administrator/Architect, AWS Solutions Architect, or ITIL v4.
- Experience with infrastructure-as-code tools such as Terraform, Ansible, or Bicep.
- Experience supporting laboratory and manufacturing IT environments (OT/IT convergence) within a pharmaceutical or life sciences setting.
- Strategic thinking and the ability to translate business needs into scalable infrastructure solutions.
- Strong communication skills - able to present complex technical topics clearly to non-technical audiences.
- Exceptional organizational and prioritization skills in a fast-paced, regulated environment.
- Collaborative leadership style with a strong emphasis on team development and cross-functional partnership.
- Data-driven decision-making and a continuous improvement mindset.
Arrowhead provides competitive salaries and an excellent benefit package.
Candidates must have current, valid authorization to work in the country where this role is located.
California Applicant Privacy Policy
Job Roles at Arrowhead Pharmaceuticals
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Get Access To All JobsTips for Finding Arrowhead Pharmaceuticals Visa Sponsorship Jobs USA
Target research-heavy roles
Arrowhead's sponsorship activity centers on specialized scientific and research positions. Focus your applications on roles in drug discovery, molecular biology, or clinical development where deep technical expertise is genuinely required and harder to source domestically.
Understand the visa types on offer
Arrowhead sponsors Green Cards, F-1 OPT, F-1 CPT, and TN visas. If you're on OPT or CPT, leading with your immediate eligibility to work without employer petition costs can make you a more attractive candidate in initial conversations.
Leverage your OPT or CPT timing strategically
Biotech companies like Arrowhead often bring on F-1 students through internships or OPT before pursuing longer-term sponsorship. Pursuing a CPT internship first is a well-worn path into permanent roles at research-focused biotechs.
Frame your background around Arrowhead's pipeline
Arrowhead specializes in RNAi-based therapeutics. Candidates with experience in RNA biology, liver-targeted therapies, or cardiometabolic disease research are far more likely to trigger sponsorship consideration than generalist applicants.
Check for open roles on Migrate Mate
Sponsorship-eligible roles at biotechs like Arrowhead aren't always flagged clearly on general job boards. Migrate Mate surfaces verified sponsors so you can filter by real sponsorship history and find open positions with confidence.
Be direct about your visa situation early
Arrowhead is a focused clinical-stage company, not a large enterprise with a dedicated immigration department. Raising your visa needs early, and demonstrating you understand the process, signals professionalism and reduces perceived friction for hiring managers.
Frequently Asked Questions
Does Arrowhead Pharmaceuticals sponsor H-1B visas?
Based on available sponsorship data, Arrowhead Pharmaceuticals does not have a recent track record of H-1B visa sponsorship. The company's sponsorship activity has focused on Green Card petitions and work authorization for F-1 students through OPT and CPT, as well as TN visas for eligible Canadian and Mexican nationals.
What visa types does Arrowhead Pharmaceuticals sponsor?
Arrowhead Pharmaceuticals sponsors EB-2 and EB-3 Green Card categories, F-1 OPT, F-1 CPT, and TN visas. This profile suggests the company is more likely to pursue permanent residency sponsorship for longer-tenured employees in specialized scientific roles rather than supporting nonimmigrant work visas at the point of initial hire.
Which roles at Arrowhead Pharmaceuticals are most likely to receive visa sponsorship?
Sponsorship at Arrowhead tends to align with its core research focus in RNA interference therapeutics. Scientists, research associates, and clinical development professionals with specialized skills in RNAi, molecular biology, or hepatology are the strongest candidates for sponsorship consideration. Corporate and administrative roles are less likely to qualify.
How do I find open visa-sponsored jobs at Arrowhead Pharmaceuticals?
Arrowhead posts openings on its own careers page, but confirming which roles come with sponsorship support isn't always straightforward. Migrate Mate aggregates verified sponsorship data so you can browse Arrowhead's open positions alongside its actual sponsorship history, helping you apply only where your visa situation genuinely fits.
How do I approach the application process at Arrowhead Pharmaceuticals as a visa-sponsored candidate?
Start by applying for roles that closely match your technical background in RNAi or therapeutic development. Arrowhead is a lean biotech, so hiring decisions move relatively quickly. Raise your visa needs during the first recruiter screen, demonstrate familiarity with their pipeline, and be prepared to discuss your current work authorization status and any applicable timelines clearly.