INTRODUCTION

If you are a current Jazz employee please apply via the Internal Career site.

Jazz Pharmaceuticals is a global biopharma company whose purpose is to innovate to transform the lives of patients and their families. We are dedicated to developing life-changing medicines for people with serious diseases — often with limited or no therapeutic options. We have a diverse portfolio of marketed medicines, including leading therapies for sleep disorders and epilepsy, and a growing portfolio of cancer treatments. Our patient-focused and science-driven approach powers pioneering research and development advancements across our robust pipeline of innovative therapeutics in oncology and neuroscience. Jazz is headquartered in Dublin, Ireland with research and development laboratories, manufacturing facilities and employees in multiple countries committed to serving patients worldwide.

Jazz Pharmaceuticals is undertaking a bold, enterprise-wide transformation to reimagine our operating model and build a patient-centric, agile, and scalable rare disease organization delivering differentiated, precise customer experiences.

ROLE AND RESPONSIBILITIES

The Executive Director, Enterprise Transformation- Tech Ops and G&A is a senior, enterprise leader responsible for setting direction and driving execution of one or more mission-critical transformation programs that shape the future of Jazz. This role operates as a trusted advisor and strategic partner to the Executive Committee (EC), with accountability for designing, orchestrating, and embedding large-scale change across functions.

This is a high-visibility, high-impact executive role for a leader who operates comfortably at the most senior levels of the organization, influences without authority, and balances strategic vision with hands-on execution. The Executive Director will lead complex, multi-year initiatives, navigate ambiguity, and challenge the status quo to deliver measurable, sustainable outcomes.

Key Responsibilities

Enterprise Transformation Strategy & Vision

• Translate Jazz’s enterprise transformation vision into integrated, multi-year strategies, roadmaps, and value cases across assigned functional or enterprise domains.
• Partner with the Chief Transformation Officer and EC members to identify, prioritize, and shape transformation initiatives that drive a high performing organization, growth, patient impact and cost efficiency.
• Define future-state operating models considering portfolio evolution, market dynamics, digital enablement, and organizational capabilities.

End-to-End Transformation Leadership

• Serve as accountable executive owner for major transformation programs, with responsibility for outcomes from concept through full-scale implementation and sustainment.
• Lead complex initiatives spanning multiple workstreams, functions, and geographies, ensuring alignment to enterprise objectives and interdependencies.
• Oversee design and implementation of new ways of working, including structure, governance, decision rights, processes, incentives, capabilities, and technology.

Executive Partnership & Influence

• Act as a thought partner and challenger to senior leaders, providing objective insight, rigorous analytics, and scenario-based recommendations.
• Engage in productive challenge with EC members and functional leaders to drive alignment, resolve trade-offs, and accelerate decision-making.
• Represent transformation progress, risks, and outcomes to the Executive Committee and other senior governance forums.

Change Leadership & Organizational Adoption

• Set the change agenda and ensure deep, lasting embedding of transformation outcomes across Jazz.
• Lead enterprise-wide change management strategies, including stakeholder engagement, communications, capability building, and cultural reinforcement.
• Anticipate and actively manage resistance, enabling leaders and teams to adopt new mindsets and behaviors aligned with a customer- and patient-first orientation.

Cross-Functional & Matrix Leadership

• Lead and develop matrixed transformation teams and workstream leaders, fostering accountability, collaboration, and high performance.
• Partner closely with executive leaders of assigned functions (e.g., R&D, Commercial, G&A, Digital) to ensure seamless integration and execution of transformation initiatives.
• Model enterprise thinking and drive solutions that optimize outcomes for Jazz as a whole, not individual functions.

Performance Management & Value Delivery

• Define enterprise-level KPIs, success metrics, and value realization plans linked to transformation objectives.
• Monitor progress rigorously, course-correct as needed, and ensure delivery of committed outcomes.
• Provide transparent, executive-level reporting on milestones, risks, and impact.

BASIC QUALIFICATIONS

• Bachelor’s degree required; advanced degree (MBA, PhD, or equivalent) preferred.
• 12+ years of progressive leadership experience in life sciences, healthcare, management consulting, or enterprise transformation roles.
• Proven record of leading large-scale, complex, cross-functional transformations with measurable business impact.
• Demonstrated ability to operate credibly at the Executive Committee level, including preparing and delivering executive-level presentations.
• Deep expertise in one or more areas such as Commercial, R&D, G&A, digital transformation, operating model design, or enterprise change.
• Strong systems thinker with the ability to connect strategy, data, operating models, and culture.
• Highly effective influencer who works across silos and leads through ambiguity without direct authority.
• Exceptional analytical, strategic, and problem-solving capabilities.
• Experience with agile, design thinking, lean, or modern change methodologies strongly preferred.

LOCATION

LI-JAZZYCHUCK

LI-REMOTE

COMPENSATION

For US BASED CANDIDATES ONLY

Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is: $272,000.00 - $408,000.00

Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidate's expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis.

At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Company's Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazz's Long Term Equity Incentive Plan.

The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits.html.

Jazz Pharmaceuticals is an equal opportunity/affirmative action employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any characteristic protected by law.