Mid Level Cytogenetic Technologist Jobs
Mid level cytogenetic technologist jobs call for professionals ready to take full ownership of complex karyotyping workflows, mentor junior analysts, and deliver diagnostic interpretations with minimal oversight. Most openings are on-site or hybrid across Healthcare & Medical Services, Education, and Technology & Software, with BayCare Health System, Quest Diagnostics, and Columbia University actively hiring at this level now.
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MAJOR RESPONSIBILITIES
- Proficiently and independently performs chromosome analysis, Fluorescent in situ Hybridization (FISH) analysis, and Microarray analysis in accordance with the department’s procedure manual and proper ISCN nomenclature.
- Performs Peripheral Blood, Bone Marrow, Amniotic Fluid, Chorionic Villus, Products of Conception, and Tumor set up, maintenance, and harvesting. Performs routine and special stain banding procedures.
- Performs sample preparation and appropriate probe application for FISH analysis.
- Proficiently and independently performs SNP Microarray procedure. Performs DNA extraction and wet lab Microarray procedures including but not limited to digestion, ligation, PCR, quantitation, fragmentation, labeling, and hybridization. Proficiently operates Spectrophotometer, scanner, Fluidics Station and System Data Transfer Server.
- Performs, monitors, and evaluates quality control, applies the principles of quality control when reporting tests. Records, reports, and monitors all QC data in the proper manner to include log books and/or worksheets. Takes appropriate corrective action when necessary and documents action(s) taken. Follows established Laboratory safety procedure in accordance with those of regulatory bodies including but not limited to OSHA, FDA, EPA, NRC. Participates in department proficiency testing.
- Correlates, reviews and documents the requisition or clinical orders with the testing procedure. Provides a preliminary diagnosis directly to the ordering provider on STAT cases which may require urgent decisions by an attending physician.
- Correlates various clinical laboratory test results, applies these results to clinical conditions and recognizes accepted normal ranges. Initiates follow-up procedures when patient results are outside normal range according to departmental policy. Identification and resolution of technical problems related to laboratory methodology, instrumentation, and procedures under direction of Laboratory Management.
- Maintains adequate inventory of supplies as required by the department.
- Participates in development and education.
MINIMUM EDUCATION AND EXPERIENCE REQUIRED
- License/Registration/Certification Required: CG(ASCP)
- Education Required: Bachelor’s Degree in Medical Technology, Biology, or related science field.
- Experience Required: Typically requires 5 years of experience in chromosome analysis of all tissue types, analysis of Microarray and/or FISH in the Cytogenetic laboratory. Must also be competent in one or more areas of the wet lab.
KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED
- 5 years of experience with Cytogenetics laboratory equipment and methodologies. Clinical internships may be applied toward experience.
- Competence in chromosome analysis of all tissue types in the Cytogenetics laboratory. Competence in analysis of Microarray and/or FISH. Competence in one or more areas of the wet lab. Basic computer literacy.
- Ability to consistently handle multi-tasking and meet established timeframes. Ability to work well in stressful situations, maintaining professional composure at all times.
- Ability to articulate knowledge of topics under discussion. Ability to effectively and appropriately communicate in all situations. Ability to balance research findings with ACL technical limitations.
- Ability to effectively implement new procedures and technologies. Ability to routinely safeguard and handle irretrievable specimen types (i.e. products of conception, amniotic fluids, chorionic villi samples, placentas, bone marrow, tumors, etc.). Able to appropriately handle hazardous chemicals, infectious biological specimens, and sharps.
PHYSICAL REQUIREMENTS AND WORKING CONDITIONS
- Hazardous chemical exposure and contact with infectious biological specimens and sharps are experienced on a daily basis.
- Position requires ability to consistently handle multi-tasking, meet established timeframes, and recognize assignments that may be delegated.
- Ability to work well in stressful situations, always maintaining professional composure.
Some instrumentation and work counter are higher than table height. Ability to lift (medium - up to 20 to 50 pounds occasionally and/or 10-25 pounds frequently and/or up to 10 pounds constantly) and use keyboard and microscopy extensively may be required, dependent upon job and shift assignment.
- Fast paced environment with established time constraints.
- Ability to routinely safeguard and handle irretrievable specimen types (i.e. products of conception, amniotic fluids, chorionic villi samples, placentas, bone marrow, tumors, etc.)
This job description indicates the general nature and level of work expected of the incumbent. It is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities required of the incumbent. Incumbent may be required to perform other related duties.
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Who's Hiring
- BayCare Health System2
- Quest Diagnostics1
- Columbia University1
- Advocate Aurora Health1
Top Industries Hiring
- Healthcare & Medical Services4
- Education1
- Technology & Software1
- Consulting & Professional Services1
Mid Level Cytogenetic Technologist Jobs: Frequently Asked Questions
How do I get a mid level cytogenetic technologist job?
Highlight your ability to independently analyze and interpret chromosomal abnormalities, manage your own caseload, and troubleshoot technical failures without supervision. Emphasize any experience with specialized techniques such as FISH, microarray, or molecular cytogenetics. Strong candidates also demonstrate familiarity with CAP and CLIA quality standards and can speak to specific cases where their diagnostic work directly shaped patient outcomes.
Which companies hire mid level cytogenetic technologists?
Companies hiring mid level cytogenetic technologists right now include BayCare Health System, Quest Diagnostics, and Columbia University, based on current listings on Migrate Mate as of July 2026. Hiring at this level comes primarily from academic medical centers, regional hospital systems, and commercial reference laboratories that need experienced technologists who can work independently and support lab quality programs.
Are there remote mid level cytogenetic technologist jobs?
Yes, though most cytogenetic roles require on-site work due to hands-on laboratory requirements. About 0% of mid level cytogenetic technologist openings are remote or hybrid as of July 2026, with those exceptions typically covering data analysis, case review, or laboratory informatics functions that do not require direct specimen handling.
How do I move up to a mid level cytogenetic technologist role?
Progression from entry level into mid level happens by building a consistent record of accurate, independent case analysis and broadening your technical repertoire beyond routine G-banding to include FISH, array CGH, or next-generation sequencing. Taking ownership of a quality control area, contributing to procedure updates, and demonstrating that you can mentor newer staff signals readiness for mid level responsibilities.
Which industries hire the most mid level cytogenetic technologists?
Mid Level cytogenetic technologist roles concentrate in Healthcare & Medical Services, Education, and Technology & Software, based on current listings on Migrate Mate as of July 2026. These sectors drive demand because they operate high-volume diagnostic programs where experienced technologists are needed to maintain throughput, ensure regulatory compliance, and support complex oncology and prenatal testing programs.