Director of Clinical Affairs Jobs

Director of Clinical Affairs jobs are open across pharmaceutical companies, medical device manufacturers, biotechnology firms, and health systems, at levels from early-career clinical specialists to senior directors, with specializations in regulatory strategy, clinical development, and medical affairs. See the openings below and apply to the ones that match your experience.

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Overview

Open roles59
Top stateCalifornia
Top employerBoston University
Top cityRedwood City, CA
Work type48% On-site
Top industryBiotechnology

Showing 5 of 59+ Director of Clinical Affairs jobs

Director, Clinical Affairs
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New 23h ago
Director, Clinical Affairs
Uwill
Remote
Clinical Support
Healthcare Administration
Medical Specialists
$90k - $110k/yr
Remote (US)
11-50

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Sterilization Assistant Clinical Affairs, Administration & Operations
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Added 1d ago
Sterilization Assistant Clinical Affairs, Administration & Operations
Boston University
Boston, Massachusetts
Healthcare Administration
Patient Services & Wellbeing
Public Health
High school diploma or GED
10,000+

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Senior / Vice President, Regulatory Science- Clinical Regulatory Affairs (Remote)
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Added 1d ago
Senior / Vice President, Regulatory Science- Clinical Regulatory Affairs (Remote)
Parexel
Remote
Accounting
Business Operations
Corporate Development & M&A
Executive Leadership & C-Suite
Remote (US)
10,000+

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Senior Regulatory Affairs Associate - Clinical Research
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Added 1d ago
Senior Regulatory Affairs Associate - Clinical Research
Baylor College of Medicine
Houston, Texas
Biotech & Life Sciences
Environmental & Physical Sciences
Laboratory Research
Research & Academia
$99k - $116k/yr
Hybrid
Bachelor's degree
5,001-10,000

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Senior Director Regulatory Affairs - Clinical
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Added 3d ago
Senior Director Regulatory Affairs - Clinical
OCUGEN OPCO INC
Malvern, Pennsylvania
Business Strategy
Corporate Development & M&A
Executive Leadership & C-Suite
Bachelor's degree

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Director of Clinical Affairs Job Market

Who's Hiring

Boston University6 open roles
Abbott5 open roles
Teleflex3 open roles

Top Industries Hiring

  • Biotechnology & Pharmaceuticals
  • Manufacturing
  • Medical Devices
  • Technology & Software
  • Healthcare & Medical Services

What Employers Look For

The qualifications that appear most often in director of clinical affairs jobs.

  • Advanced degree (MD, PharmD, or PhD) in a life sciences discipline
  • 5 or more years of clinical or medical affairs experience in pharma, biotech, or medical devices
  • Direct experience with FDA regulatory submissions or clinical trial management
  • Proven ability to lead cross-functional teams across medical, regulatory, and commercial functions
  • Deep knowledge of GCP guidelines and ICH standards
  • Experience developing clinical evidence strategies or medical communication plans

Tips for Your Director of Clinical Affairs Job Search

Tailor your resume for regulatory depth

Hiring managers for director of clinical affairs roles expect your resume to show direct experience with IND or NDA submissions, clinical trial oversight, or FDA engagement. Generic leadership bullets won't cut it. Name the therapeutic areas, phases, and regulatory milestones you've owned.

Distinguish medical affairs from clinical development

Job postings often blur these two functions, but your resume should make your lane clear. If your background is in KOL engagement and medical education, say so explicitly. If it's in trial design and protocol development, lead with that. Ambiguity costs you interviews.

Target companies by pipeline stage

Early-stage biotechs need directors who can build clinical infrastructure from scratch. Commercial-stage pharma needs someone to maintain compliant field medical teams. Knowing which stage you're suited for lets you apply to roles where your experience maps directly to the company's current need.

Apply early to roles that fit

Migrate Mate lists director of clinical affairs openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Prepare for a cross-functional interview panel

Expect interviews with R&D, regulatory affairs, commercial, and sometimes the chief medical officer. Each stakeholder evaluates a different dimension of your fit. Practice articulating how your clinical decisions have supported both regulatory approval timelines and commercial readiness.

Negotiate scope before you negotiate compensation

Before accepting an offer, clarify direct report structure, budget authority, and whether the role owns clinical strategy or executes it. Directors hired into poorly scoped roles frequently face title inflation with no real authority. Get the reporting lines and decision rights in writing.

Director of Clinical Affairs Jobs: Frequently Asked Questions

Which companies are hiring the most director of clinical affairss?

The companies hiring the most director of clinical affairss right now include Boston University, Abbott, and Teleflex, with the largest share of openings in California, Massachusetts, and Minnesota, based on current listings on Migrate Mate as of November 2026. Activity tends to cluster around companies with active late-stage pipelines or recent product approvals.

How many director of clinical affairs jobs are remote?

About 52% of director of clinical affairs openings are fully remote or hybrid as of November 2026, reflecting how much of the role's core work can be done without a fixed office. Medical affairs functions, including KOL strategy and medical education, tend to offer the most remote flexibility, while roles tied to active clinical trial sites typically require more on-site presence.

How do you become a director of clinical affairs?

Most directors of clinical affairs begin with an advanced clinical or scientific degree, then build experience in clinical research, regulatory affairs, or medical affairs at the manager or associate director level. From there, you progress by owning larger cross-functional projects, managing direct reports, and developing fluency in both scientific and commercial strategy. Therapeutic area expertise in a high-demand field accelerates the path.

How do you get hired as a director of clinical affairs with limited experience?

If you're newer to the director level, the most effective approach is to target small or early-stage biotechs where the scope is narrower and hiring is based on potential alongside credentials. Emphasize hands-on clinical or regulatory project ownership rather than team size, and build a portfolio of cases where you drove a clinical or medical decision from conception to execution.

What does the director of clinical affairs interview process look like?

The process typically starts with a recruiter screen, followed by separate conversations with HR, the hiring manager, and a cross-functional panel that may include heads of regulatory, commercial, and R&D. Many companies add a case presentation where candidates are asked to outline a clinical development strategy or respond to a real-world regulatory scenario. Final rounds often include a conversation with a chief medical officer or executive.

Where can I find and apply to director of clinical affairs jobs?

You can find and apply to director of clinical affairs jobs on Migrate Mate, which lists current openings from companies across the United States. Search for roles that fit your background in therapeutic area, function, and seniority, then apply directly to each listing that matches your experience.

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