Senior Level Finance And Accounting Jobs
Senior level finance and accounting jobs place experienced professionals in charge of financial strategy, audit oversight, and the cross-functional teams that deliver results. Roles are concentrated in Biotechnology & Pharmaceuticals, Manufacturing, and Staffing & Recruiting, with 10% offering remote or hybrid arrangements, and employers like TEAM, Vaco, and Jobot hiring at this level now.
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Job Title: Director / Associate Director, Clinical Finance & Accounting
Location: San Francisco, CA
Position Description
The Director / Associate Director, Clinical Finance & Accounting will report directly to the Senior Director of Finance and serve as the finance lead supporting the Company's clinical development organization. This role owns the financial oversight of clinical studies from planning through closeout, with primary accountability for clinical accrual preparation, study forecasting, and CRO financial management. Working directly with Clinical Operations, Accounting, and external CRO partners, this individual will ensure timely and supportable recognition of clinical trial expenses; develop reliable forecasts for current and future studies; and provide actionable financial insights to guide resource allocation and strategic decision-making.
Position Responsibilities
- Lead the preparation and review of monthly and quarterly clinical trial accruals.
- Serve as the primary Finance partner to CROs and other clinical vendors.
- Develop and maintain forecasts for ongoing clinical studies and future development programs.
- Partner with Clinical Operations to translate study execution assumptions into financial projections.
- Manage study budgets, vendor commitments, and clinical development spending.
- Provide financial analysis, variance reporting, and portfolio planning support to executive leadership.
Experience And Required Skills
- Requires a strong financial background with a bachelor's degree in business, accounting or finance and CPA certification.
- Minimum of 8+ years of experience in an accounting/finance role working in fast growing life sciences organizations.
- Experience supporting outsourced clinical development programs and working directly with CROs.
- Experience with clinical trial budgeting, forecasting, and accruals across multiple studies.
- Experience with ERP and financial planning systems (e.g., NetSuite, Adaptive).
- Self-starter with good analytical skills, builds strong relationships, has a proven track record of client/vendor management, and possesses excellent business communications skills including writing and presentation capabilities.
- Ability to communicate (orally and in writing) professionally when dealing with company leadership, employees and vendors.
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Who's Hiring



Top Industries Hiring
- Biotechnology & Pharmaceuticals
- Manufacturing
- Staffing & Recruiting
- Technology & Software
- Accounting & Auditing
Senior Level Finance And Accounting Jobs: Frequently Asked Questions
How do I get a senior level finance and accounting job?
Employers hiring at the senior level look for candidates who have owned outcomes, not just executed tasks. A strong application demonstrates deep technical expertise in areas like financial modeling, regulatory compliance, or audit leadership, paired with examples of mentoring junior staff or driving process improvements. Certifications such as CPA or CFA carry real weight, and a portfolio of increasingly complex projects signals readiness for this tier.
Which companies hire senior level finance and accountings?
Companies hiring senior level finance and accountings right now include TEAM, Vaco, and Jobot, based on current listings on Migrate Mate as of September 2026. Hiring at this level comes from a broad mix of large enterprises with dedicated finance departments, regional firms building out leadership depth, and fast-growing companies that need experienced professionals to own their financial operations.
Are there remote senior level finance and accounting jobs?
Yes, remote and hybrid arrangements are common at the senior level, particularly for roles focused on financial analysis, FP&A, and advisory functions. About 10% of senior level finance and accounting openings are remote or hybrid as of September 2026, reflecting employer recognition that experienced professionals deliver strong results without requiring full on-site presence.
What makes a finance and accounting role senior level?
Senior level roles are defined by ownership and scope rather than task completion. Professionals at this stage set financial direction, own outcomes for significant revenue or cost centers, lead audits or complex reporting cycles, and mentor junior and mid-level staff. The expectation shifts from following established processes to shaping them, and from executing decisions to making them.
Which industries hire the most senior level finance and accountings?
Senior level finance and accounting roles concentrate in Biotechnology & Pharmaceuticals, Manufacturing, and Staffing & Recruiting, based on current listings on Migrate Mate as of September 2026. These sectors drive demand because their financial complexity, regulatory requirements, and scale require experienced professionals who can lead reporting functions, manage risk, and support executive decision-making at a high level.