H-1B Visa Director Of Research Operations Jobs
Director of Research Operations roles qualify as H-1B visa specialty occupations, typically requiring a bachelor's degree or higher in a research-related field. Universities, pharmaceutical companies, and research institutes are among the most active H-1B sponsors for this title, making institutional and industry employers your strongest targets.
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The Buck Institute for Research on Aging is seeking a full-time Bioinformatics and Data Scientist or Postdoctoral Researcher to join a collaborative research team focused on aging, multi-omics, computational biology, and translational data science. This position offers a unique opportunity to work in an academic research environment with a close-knit, interdisciplinary team while collaborating with leading experts in aging biology, bioinformatics, clinical research, and computational science. The successful candidate will contribute to a five-year government-funded project focused on advancing computational and multi-omics approaches to better understand human aging, biological resilience, and healthspan. This role will support broader nationwide efforts to develop data-driven approaches that may ultimately improve how aging and age-related disease risk are measured, modeled, and addressed. The ideal candidate will have strong experience in bioinformatics, statistics, computational biology, human omics data analysis, and scientific communication. The position is well suited for an independent, highly motivated scientist who enjoys working across disciplines and contributing to both discovery-driven and translational research.
Key Responsibilities
2. Analyze, curate, and manage research data
- Perform bioinformatics and data science analyses. The successful candidate will analyze diverse biological and clinical datasets, including but not limited to:
- Proteomics
- Metabolomics
- Methylomics
- Survey data
- Integrative multi-omics datasets
- Human biological aging and omics-clock data
- Drug repurposing analyses
- Enrichment and pathway analyses
- Dimensionality reduction and clustering
- Classification methods, including random forests and support vector machines
- Neural network-based approaches
- Simple and multiple linear regression
- Parametric and non-parametric statistical analyses
Responsibilities will include:
- Curating, organizing, and preparing data for analysis and upload to central repositories
- Supporting data harmonization across projects, cohorts, and collaborators in accordance with data use agreements
- Reviewing and improving standard operating procedures for data transfer, quality control, and management
- Coordinating with internal and external teams to ensure timely collection, transfer, and analysis of data
- Attending project meetings and contributing to improvements in data workflows, systems, and documentation
- Ensuring data quality, reproducibility, and compliance with project requirements
3. Collaborate with scientific and administrative teams
The candidate will work closely with staff members, research scientists, computational biologists, principal investigators, and external collaborators. Responsibilities may include:
- Contributing to grant applications, progress reports, and scientific proposals
- Supporting manuscript preparation and journal article writing
- Creating publication-quality figures, tables, and data visualizations
- Presenting analyses and findings to interdisciplinary research teams
- Helping translate complex computational results into clear biological and scientific interpretations
Qualifications
Required Education and Experience
- Strong background in both human biology and bioinformatics
- PhD in Computational Biology, Bioinformatics, Data Science, Biostatistics, Systems Biology, Computer Science, or a related field
- Minimum of 2 years of professional experience in a biological, biomedical, or computational research environment
- Strong proficiency in R, Python, and Bash scripting
- Demonstrated experience analyzing biological or biomedical datasets
- Experience developing, implementing, and running bioinformatics workflows
Required Skills
- Strong analytical, mathematical, and creative problem-solving skills
- Excellent written and oral communication skills
- Ability to work both independently and collaboratively in a team-based research environment
- Strong organizational skills and attention to detail
- Ability to prioritize and execute multiple tasks across concurrent projects
- Experience with reproducible data analysis practices and documentation
- Ability to communicate technical results to both computational and non-computational audiences
- Interest in applying large language models, agentic AI, or related computational tools to biomedical research workflows
Preferred Qualifications
- Experience with FDA approval process
- Experience with building apps
Compensation And Benefits
- Salary range: $80,000–$85,000, commensurate with experience
- Full-time, onsite position
- Exciting, collaborative work environment at the forefront of aging research
- Opportunity to work with state-of-the-art technologies and interdisciplinary scientific teams
- Generous benefits package, including:
- Health insurance
- Paid parental leave
- Generous paid time off
- 401(k) with 5% employer match
- Work visa sponsorship available for qualified candidates
About The Buck Institute
Our success will ultimately change healthcare. At the Buck Institute for Research on Aging, we aim to end the threat of age-related diseases for this and future generations by bringing together the most capable and passionate scientists from a broad range of disciplines to identify and impede the ways in which we age. The Buck is an independent, nonprofit institution located in Marin County, California, with the goal of increasing human healthspan, or the healthy years of life. Globally recognized as a pioneer and leader in efforts to target aging — the number one risk factor for diseases including Alzheimer’s disease, Parkinson’s disease, cancer, macular degeneration, heart disease, and diabetes — the Buck seeks to help people live better longer. We are an equal opportunity employer and strive to create an atmosphere where diversity of identity, experience, and background are welcomed, valued, and supported. Candidates who contribute to this diversity are strongly encouraged to apply.
To Apply
Interested candidates should click the Apply button to complete the online application. Please upload both:
- Your CV
- A brief statement of research interests, including the names and contact information for three references
Position Summary
The Buck Institute for Research on Aging is seeking a full-time Bioinformatics and Data Scientist or Postdoctoral Researcher to join a collaborative research team focused on aging, multi-omics, computational biology, and translational data science. This position offers a unique opportunity to work in an academic research environment with a close-knit, interdisciplinary team while collaborating with leading experts in aging biology, bioinformatics, clinical research, and computational science. The successful candidate will contribute to a five-year government-funded project focused on advancing computational and multi-omics approaches to better understand human aging, biological resilience, and healthspan. This role will support broader nationwide efforts to develop data-driven approaches that may ultimately improve how aging and age-related disease risk are measured, modeled, and addressed. The ideal candidate will have strong experience in bioinformatics, statistics, computational biology, human omics data analysis, and scientific communication. The position is well suited for an independent, highly motivated scientist who enjoys working across disciplines and contributing to both discovery-driven and translational research.
Key Responsibilities
2. Analyze, curate, and manage research data
- Perform bioinformatics and data science analyses. The successful candidate will analyze diverse biological and clinical datasets, including but not limited to:
- Proteomics
- Metabolomics
- Methylomics
- Survey data
- Integrative multi-omics datasets
- Human biological aging and omics-clock data
- Drug repurposing analyses
- Enrichment and pathway analyses
- Dimensionality reduction and clustering
- Classification methods, including random forests and support vector machines
- Neural network-based approaches
- Simple and multiple linear regression
- Parametric and non-parametric statistical analyses
Responsibilities will include:
- Curating, organizing, and preparing data for analysis and upload to central repositories
- Supporting data harmonization across projects, cohorts, and collaborators in accordance with data use agreements
- Reviewing and improving standard operating procedures for data transfer, quality control, and management
- Coordinating with internal and external teams to ensure timely collection, transfer, and analysis of data
- Attending project meetings and contributing to improvements in data workflows, systems, and documentation
- Ensuring data quality, reproducibility, and compliance with project requirements
3. Collaborate with scientific and administrative teams
The candidate will work closely with staff members, research scientists, computational biologists, principal investigators, and external collaborators. Responsibilities may include:
- Contributing to grant applications, progress reports, and scientific proposals
- Supporting manuscript preparation and journal article writing
- Creating publication-quality figures, tables, and data visualizations
- Presenting analyses and findings to interdisciplinary research teams
- Helping translate complex computational results into clear biological and scientific interpretations
Qualifications
Required Education and Experience
- Strong background in both human biology and bioinformatics
- PhD in Computational Biology, Bioinformatics, Data Science, Biostatistics, Systems Biology, Computer Science, or a related field
- Minimum of 2 years of professional experience in a biological, biomedical, or computational research environment
- Strong proficiency in R, Python, and Bash scripting
- Demonstrated experience analyzing biological or biomedical datasets
- Experience developing, implementing, and running bioinformatics workflows
Required Skills
- Strong analytical, mathematical, and creative problem-solving skills
- Excellent written and oral communication skills
- Ability to work both independently and collaboratively in a team-based research environment
- Strong organizational skills and attention to detail
- Ability to prioritize and execute multiple tasks across concurrent projects
- Experience with reproducible data analysis practices and documentation
- Ability to communicate technical results to both computational and non-computational audiences
- Interest in applying large language models, agentic AI, or related computational tools to biomedical research workflows
Preferred Qualifications
- Experience with FDA approval process
- Experience with building apps
Compensation And Benefits
- Salary range: $80,000–$85,000, commensurate with experience
- Full-time, onsite position
- Exciting, collaborative work environment at the forefront of aging research
- Opportunity to work with state-of-the-art technologies and interdisciplinary scientific teams
- Generous benefits package, including:
- Health insurance
- Paid parental leave
- Generous paid time off
- 401(k) with 5% employer match
- Work visa sponsorship available for qualified candidates
About The Buck Institute
Our success will ultimately change healthcare. At the Buck Institute for Research on Aging, we aim to end the threat of age-related diseases for this and future generations by bringing together the most capable and passionate scientists from a broad range of disciplines to identify and impede the ways in which we age. The Buck is an independent, nonprofit institution located in Marin County, California, with the goal of increasing human healthspan, or the healthy years of life. Globally recognized as a pioneer and leader in efforts to target aging — the number one risk factor for diseases including Alzheimer’s disease, Parkinson’s disease, cancer, macular degeneration, heart disease, and diabetes — the Buck seeks to help people live better longer. We are an equal opportunity employer and strive to create an atmosphere where diversity of identity, experience, and background are welcomed, valued, and supported. Candidates who contribute to this diversity are strongly encouraged to apply.
To Apply
Interested candidates should click the Apply button to complete the online application. Please upload both:
- Your CV
- A brief statement of research interests, including the names and contact information for three references
See all 5,358+ H-1B Visa Director Of Research Operations Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new H-1B Visa Director Of Research Operations Jobs.
Get Access To All JobsTips for Finding H-1B Visa Sponsorship in Director Of Research Operations
Align your credentials to specialty occupation standards
USCIS requires your degree field to directly relate to the role. A Director of Research Operations position supported by a degree in public health, biomedical science, or research administration strengthens your petition against RFE risk.
Target research-intensive institutions with LCA history
Universities, hospital systems, and pharma companies file LCAs regularly for research operations roles. Search Migrate Mate to filter employers with verified H-1B filing history specifically for research and operations management positions.
Verify the prevailing wage tier before accepting an offer
Run the OFLC Wage Search using the correct SOC code for your role before negotiating compensation. Your offered salary must meet the DOL prevailing wage, and a lower-tier offer can delay LCA certification.
Confirm your employer's E-Verify enrollment early
H-1B sponsors must be enrolled in E-Verify. Directors stepping into roles at smaller research nonprofits or startups should ask HR to confirm enrollment status before your petition is filed, not after.
Document your oversight scope for the specialty occupation test
USCIS scrutinizes operations and management titles. A detailed job duties letter showing you direct research methodology, manage IRB compliance, or oversee grant administration builds the specialty occupation case more effectively than a generic job description.
Time your petition filing around the cap and grace period
If you're transitioning from OPT or another status, your H-1B start date can't precede October 1. The 60-day grace period after your prior status ends sets a hard deadline for your employer to file.
H-1B Visa Director Of Research Operations: Frequently Asked Questions
Does a Director of Research Operations role qualify as an H-1B specialty occupation?
Yes, provided the role requires at least a bachelor's degree in a specific field such as research administration, life sciences, public health, or a related discipline. USCIS will review the job duties, not just the title. Roles with broad generalist duties and no degree field requirement are more likely to receive an RFE challenging specialty occupation status.
Which types of employers sponsor H-1B visas for research operations directors?
Research universities, academic medical centers, pharmaceutical companies, government contractors, and large nonprofit research institutes are the most consistent H-1B sponsors for this title. These organizations file LCAs routinely and have established HR processes for sponsorship. You can browse employers with verified H-1B filing history for research operations roles on Migrate Mate.
What SOC code applies to Director of Research Operations for H-1B prevailing wage purposes?
The most commonly applied SOC code is 11-9121 (Natural Sciences Managers) or 11-1021 (General and Operations Managers), depending on how your employer characterizes the role. The DOL prevailing wage is tied to the SOC code selected on the LCA, so confirming the correct code with your employer before filing affects both compliance and compensation benchmarking.
Can a research operations director role face H-1B RFEs, and what triggers them?
Yes. USCIS frequently issues RFEs for operations and management titles when the job duties appear administrative rather than requiring specialized theoretical knowledge. Vague descriptions referencing general oversight, budgeting, or staff management without grounding them in a specific research domain increase RFE risk. A detailed duties letter tied explicitly to a scientific or technical field reduces that exposure significantly.
How does O*NET classify Director of Research Operations for H-1B purposes?
O*NET classifies closely related roles under Natural Sciences Managers and Management Analysts, both of which fall in Job Zone 4 or 5, supporting the specialty occupation argument. Referencing the O*NET profile in your petition documentation helps demonstrate that the position routinely requires advanced knowledge and a degree in a specific field, which is central to USCIS's specialty occupation analysis.