Head Of People Operations Jobs in Pennsylvania
Head Of People Operations jobs in Pennsylvania are open across Philadelphia, Allentown, and Blue Bell and other Pennsylvania metros, with employers like Air Products, Bentley Systems, and Brightview hiring at every experience level. Find a role that fits below and apply directly.
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Job Title: Head of Vaccine Research and Development Project Management
Location: Swiftwater, PA / Waltham, MA
About the Job
Join the team protecting half a billion lives every year with next-gen science, mRNA innovation, and AI-driven breakthroughs. In Vaccines, you’ll help advance prevention on a global scale - and shape the future of immunization.
The Head of Vaccine Global Project Management leads New Vaccines R&D project management function, translating corporate strategy into executable project plans while ensuring strategic alignment, operational excellence, and delivery of complex vaccine development programs.
You will be responsible for establishing best-in-class project management standards, governance frameworks, and AI/Digital-enabled practices across the portfolio — with the ultimate goal of delivering vaccines at optimal time-to-market, within budget, and in full alignment with Sanofi's strategic objectives.
You will lead a team of 20+, with 4 direct reports:
- Head of France Project Management
- Head of North America & International Project Management
- Risk & Compliance Manager
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- Administrative Support
About Sanofi
We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.
Main responsibilities:
- Set the strategic direction for Vaccines R&D project management by establishing best-in-class standards, governance frameworks, and AI/Digital-enabled practices across the portfolio
- Drive portfolio execution by overseeing end-to-end delivery against scope, schedule, cost, and quality baselines — monitoring pipeline health and ensuring timely escalation and corrective action
- Lead risk management and compliance across all New Vaccine projects, ensuring proactive risk identification, robust lessons learned processes, and readiness for internal audits
- Enable effective governance through transparent Stage Gate processes, acting as TARC Secretary and key liaison between Vaccine R&D and Corporate Portfolio Management
- Inspire and develop talent by leading a global team of 15+ project managers, fostering a culture of accountability, continuous improvement, and digital innovation
- Oversee financial and resource planning, providing strategic input to resources and cost forecasts as well as ensuring alignment across R&D, Franchise, and Manufacturing & Supply
Dimensions / Scope:
- Strategic Visibility: Direct interface with Vaccines R&D Leadership Team Corporate Portfolio Management, and external funding entities (BARDA and others)
- Global Impact: Lead an international team across multiple R&D sites (4 direct reports, total of 15+ Project Managers, Functional lead for Project planning Managers in Budapest)
- Innovation at the Forefront: Drive the integration of AI and digital tools into the future of project management for Vaccine RD project Management
- Leadership Platform: Build and develop the next generation of project management talent within Sanofi's Vaccines organization
About You
Education:
- MS and 12+ years of leadership experience in pharmaceutical R&D project/program management OR PhD and 8+ years of leadership experience in pharmaceutical R&D project/program management
- Advanced degree in Project Management
- Professional certification: PMP, Agile, or equivalent
- Previous experience of pharmaceutical R&D project and/or portfolio management, including management responsibilities and cross functional governance contributions
- MBA preferred but not required.
Knowledge & Technical Expertise:
- Deep knowledge of the end-to-end vaccine/pharma development value chain (Research Clinical Industrialization Registration Launch)
- Proven leadership in complex, global, matrixed environments
- Expertise in PM methodologies: PMBOK, Hybrid, Agile
- Proven expertise in R&D Risk Management
- Business acumen and financial management in high-investment pharmaceutical contexts
- Experience in digital planning tool or AI/digital solution rollout
Key Skills & Abilities:
- Strategic & Tactical Thinking — Translates strategy into execution frameworks
- People Leadership — Mobilizes global teams and inspires action
- Influence & Stakeholder Management — Communicates effectively at operational and executive levels
- Change Management — Guides teams through transformation with confidence
- Decision-Making & Prioritization — Acts with clarity under pressure
- Coaching & Development — Builds capability through structured support
- Cross-Functional Agility — Operates effectively in multicultural, worldwide matrix environments
- Digital/AI Mindset — Anticipates and drives innovation in project management
- Languages: English fluent (required); French fluent (preferred)
Why Choose Us?
- Bring the miracles of science to life alongside a supportive, future-focused team.
- Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
- Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
- Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.
See All 6 Head Of People Operations Jobs in Pennsylvania
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Find JobsHead Of People Operations Jobs by City in Pennsylvania
Where Pennsylvania roles are concentrated, by current openings.
Head Of People Operations Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring
- Air Products1

- Bentley Systems1

- Brightview1

- Duolingo1

- Sanofi1

Top Industries Hiring
- Technology & Software2
- Biotechnology & Pharmaceuticals1
- Chemicals & Materials1
- Construction & Real Estate1
- Healthcare & Medical Services1
What Pennsylvania Employers Look For
The qualifications that appear most often in head of people operations jobs across Pennsylvania.
- 7 or more years of progressive HR leadership experience, including managing HR teams
- Demonstrated experience building or scaling people programs across the full employee lifecycle
- Proficiency with an HRIS platform such as Workday, BambooHR, or Rippling
- Bachelor's degree in human resources, business administration, organizational psychology, or a related field
- Experience developing and executing talent acquisition, retention, and workforce planning strategies
- SHRM-SCP, SPHR, or equivalent senior HR certification preferred by many employers
Head Of People Operations Jobs in Pennsylvania: Frequently Asked Questions
How many head of people operations jobs are there in Pennsylvania?
There are 6+ head of people operations openings in Pennsylvania on Migrate Mate as of June 2026, with the most roles in Philadelphia, Allentown, and Blue Bell. New positions post regularly as employers across Pennsylvania hire.
How much do head of people operationses make in Pennsylvania?
Head of people operationses in Pennsylvania earn a median of about $133,060 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $80,940 for the lowest 10% to over $222,690 for the top 10%. Pay rises with experience, specialty, and employer.
Which Pennsylvania cities have the most head of people operations jobs?
Philadelphia, Allentown, and Blue Bell have the most head of people operations openings in Pennsylvania right now, with additional roles spread across smaller metros statewide.
Which companies hire head of people operationss in Pennsylvania?
Employers hiring head of people operationss in Pennsylvania include Air Products, Bentley Systems, and Brightview, based on current listings on Migrate Mate as of June 2026.
Are there remote head of people operations jobs in Pennsylvania?
Yes. About 17% of head of people operations openings tied to Pennsylvania are remote or hybrid as of June 2026. The rest are on-site roles based in Pennsylvania metros.
How do I apply for head of people operations jobs in Pennsylvania?
You can apply to head of people operations jobs in Pennsylvania directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Pennsylvania location, then apply to each one that fits.
See All 6 Head Of People Operations Jobs in Pennsylvania
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