IT Systems Specialist Jobs in Missouri

IT Systems Specialist jobs in Missouri are open across St. Louis, Columbia, and Kansas City and other Missouri metros, with employers like Connection, Washington University in St. Louis, and CBIZ hiring at every experience level. Find a role that fits below and apply directly.

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Overview

Open roles13+
Top employerConnection
Top citySt. Louis, MO
Cities hiring7
Work type85% On-site
Top industryTechnology

Showing 5 of 13+ IT Systems Specialist jobs

Collabera
Operations & Systems Specialist III / Citrix Systems Manager
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Collabera
Added 2mo ago
Operations & Systems Specialist III / Citrix Systems Manager
Collabera
St. Louis, Missouri
IT Support & Systems Administration
Technical Product & Program Management
IT Support
Systems Administration
On-Site
Associate's

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Freeman Health System
Desktop Support Specialist
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Freeman Health System
Added 1w ago
Desktop Support Specialist
Freeman Health System
Joplin, Missouri
IT Support & Systems Administration
IT Support
On-Site
Associate's
1,001-5,000

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Federal Reserve Bank of St. Louis
Information Technology (IT) Risk Specialist
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Federal Reserve Bank of St. Louis
Added 1w ago
Information Technology (IT) Risk Specialist
Federal Reserve Bank of St. Louis
St. Louis, Missouri
Compliance & Legal
Cybersecurity
IT Support & Systems Administration
Compliance & Risk
IT Support
$97k - $162k/yr
On-Site
Bachelor's
1,001-5,000

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National Information Solutions Cooperative (NISC)
Network Specialist
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National Information Solutions Cooperative (NISC)
Added 2w ago
Network Specialist
National Information Solutions Cooperative (NISC)
Lake Saint Louis, Missouri
IT Support & Systems Administration
Customer Service & Support
IT Support
Network Engineering
Customer Support
Hybrid
Associate's
1,001-5,000

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Washington University in St. Louis
Technical Support Specialist II
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Washington University in St. Louis
Added 3w ago
Technical Support Specialist II
Washington University in St. Louis
St. Louis, Missouri
IT Support & Systems Administration
Technical Product & Program Management
IT Support
$25 - $39/hr
On-Site
High School
10,000+

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See All 13 IT Systems Specialist Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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IT Systems Specialist Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

St. Louis
5 jobs
Columbia
2 jobs
Kansas City
2 jobs
Joplin
1 jobs
Lake Saint Louis
1 jobs
Lee's Summit
1 jobs
Maryland Heights
1 jobs

IT Systems Specialist Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

  • Connection
    Connection2
  • Washington University in St. Louis
    Washington University in St. Louis2
  • CBIZ
    CBIZ1
  • Collabera
    Collabera1
  • Federal Reserve Bank of St. Louis
    Federal Reserve Bank of St. Louis1

Top Industries Hiring

  • Technology & Software5
  • Banking & Financial Services2
  • Education2
  • Accounting & Auditing1
  • Consulting & Professional Services1

What Missouri Employers Look For

The qualifications that appear most often in IT systems specialist jobs across Missouri.

  • Proficiency with Active Directory, Group Policy, and Windows Server administration
  • Experience supporting and troubleshooting enterprise endpoints running Windows and macOS
  • Familiarity with networking fundamentals including TCP/IP, DNS, DHCP, and VPN configurations
  • CompTIA A+, Network+, or a Microsoft certification such as MS-900 or MD-102
  • Experience with a helpdesk or ITSM ticketing platform such as ServiceNow, Jira Service Management, or Zendesk
  • Associate or bachelor's degree in information technology, computer science, or a related field, or equivalent hands-on experience

IT Systems Specialist Jobs in Missouri: Frequently Asked Questions

How many IT systems specialist jobs are there in Missouri?

There are 13+ IT systems specialist openings in Missouri on Migrate Mate as of June 2026, with the most roles in St. Louis, Columbia, and Kansas City. New positions post regularly as employers across Missouri hire.

Which Missouri cities have the most IT systems specialist jobs?

St. Louis, Columbia, and Kansas City have the most IT systems specialist openings in Missouri right now, with additional roles spread across smaller metros statewide.

Which companies hire IT systems specialists in Missouri?

Employers hiring IT systems specialists in Missouri include Connection, Washington University in St. Louis, and CBIZ, based on current listings on Migrate Mate as of June 2026.

Are there remote IT systems specialist jobs in Missouri?

Yes. About 15% of IT systems specialist openings tied to Missouri are remote or hybrid as of June 2026. The rest are on-site roles based in Missouri metros.

How do I apply for IT systems specialist jobs in Missouri?

You can apply to IT systems specialist jobs in Missouri directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Missouri location, then apply to each one that fits.

See All 13 IT Systems Specialist Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

Find IT Systems Specialist Jobs