Laboratory Jobs in Durham, NC
Laboratory jobs in Durham, North Carolina are in strong demand, concentrated in Research Triangle Park, the Chesterfield district, and the Midtown area across life sciences, academic research, and clinical diagnostics. Employers hiring right now include GRAIL, Labcorp, and NVE. Scan the live roles below and apply to whichever ones fit.
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MainStreet Family Care operates over 60 fast-growing urgent care clinics across Alabama, Florida, Georgia, and North Carolina. As we continue expanding access to high-quality healthcare in rural communities throughout the Southeastern U.S., our mission remains the same: quality care, close to home.
Due to continued growth, we are seeking a Laboratory General Supervisor to join our clinical team in the Wake Forest, NC area. This role plays a vital part in delivering accurate, timely diagnostic results through high-complexity real-time PCR testing and other laboratory procedures that directly impact patient care.
The Laboratory General Supervisor is responsible for all testing duties, quality standards, and MainStreet Family Care values. This position supports providers and lab techs by producing reliable laboratory results that enable efficient diagnosis and treatment.
Key Responsibilities
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Perform CLIA high-complexity, real-time PCR testing in accordance with established protocols and regulatory requirements
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Collect, prepare, process, and analyze patient specimens
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Accurately document laboratory results in the electronic medical record
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Perform quality control procedures, calibration, and routine maintenance on laboratory equipment
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Ensure compliance with CLIA, OSHA, HIPAA, and infection control standards
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Prepare and manage specimens for internal and external testing as needed
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Monitor laboratory inventory, reagents, and expiration dates
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Identify, troubleshoot, and report testing discrepancies, equipment issues, or quality concerns
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Maintain a clean, organized, and safe laboratory environment
- Collaborate with providers and clinical staff to support efficient operations
- Providing supervision for day-to-day test performance
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Perform advanced molecular diagnostic testing in a growing healthcare organization
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Make a direct impact on patient outcomes through accurate, rapid diagnostics
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Support healthcare access in traditionally underserved communities
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Competitive compensation with strong benefits and growth opportunities
Minimum Qualifications
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Medical laboratory certification, or a Bachelor's degree in chemical, biological, clinical, or medical laboratory science that is compliant with CLIA standards.
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Two (2) years of clinical laboratory experience, including molecular or PCR-based testing
Preferred Qualifications
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Five (5) years of clinical laboratory experience
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Experience performing high-complexity real-time PCR testing in a regulated laboratory environment
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Experience in urgent care, primary care, or high-volume clinical settings
Required Skills, Knowledge, and Abilities
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Proficiency in real-time PCR and molecular diagnostic techniques
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Knowledge of high-complexity laboratory testing standards and CLIA requirements
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Strong attention to detail and quality assurance practices
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Ability to troubleshoot testing and equipment issues
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Effective communication and teamwork skills
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Ability to work efficiently in a fast-paced environment
Schedule
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Approximately 30-40 hours per week
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10-hour shifts, scheduled across 7 days per week
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Rotating shifts, including weekends and holidays as needed
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Schedule may vary based on operational and testing volume needs
Compensation & Benefits
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Position begins at $25/hr
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401(k) with company match
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Health, dental, and vision insurance contribution
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Paid time off (PTO)
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Employee Assistance Program
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Referral programs
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Find Laboratory JobsLaboratory Job Market in Durham
Who's Hiring
- GRAIL17

- Labcorp17

- NVE9

- Onterris9

- DLR9

Top Industries Hiring
- Biotechnology & Pharmaceuticals
- Healthcare & Medical Services
Laboratory Jobs in Durham: Frequently Asked Questions
How do I get a laboratory job in Durham?
Focus your search on Durham's dense cluster of life sciences companies, university research programs, and hospital systems, which drive the majority of local openings. Research Triangle Park sits just outside the city and is home to pharmaceutical, biotech, and contract research organizations that hire continuously. Candidates who can point to hands-on bench experience, familiarity with GLP or GMP environments, or specialized instrument training tend to move faster through the process here.
Which companies hire laboratorys in Durham?
Durham laboratory roles are posted by GRAIL, Labcorp, and NVE and others right now, based on current listings on Migrate Mate as of August 2026. The employer mix here reflects Durham's position within the Research Triangle, drawing from large pharmaceutical manufacturers, academic medical centers, and specialized contract testing labs.
Are there remote laboratory jobs in Durham?
Yes, though only for certain functions, since most laboratory work requires physical access to equipment and samples. About 60% of laboratory openings tied to Durham are remote or hybrid as of August 2026, which is lower than other fields given the hands-on nature of the work. The roles most likely to carry remote flexibility are data analysis, quality documentation, regulatory affairs, and lab informatics positions tied to Durham employers.
How can I get a laboratory job in Durham with little or no experience?
The most realistic entry path in Durham is a laboratory technician or research assistant role at one of the city's university-affiliated research programs or hospital systems, which regularly hire candidates still building their credentials. Duke University Health System and North Carolina Central University both run labs that onboard early-career staff. Volunteering in a research setting, completing a community college lab science certificate, or landing a temp position through a contract research organization are all effective ways to build a Durham-relevant work history quickly.
Which industries hire the most laboratorys in Durham?
Most laboratory openings in Durham sit in Biotechnology & Pharmaceuticals and Healthcare & Medical Services, per current listings on Migrate Mate as of August 2026. Durham's location within Research Triangle Park and its concentration of academic medical infrastructure make those sectors the primary and most consistent sources of laboratory hiring in the city.
Related Jobs in North Carolina
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