Laboratory Jobs in South Dakota
Laboratory jobs in South Dakota are open across Sioux Falls, Rapid City, and North Sioux City and other South Dakota metros, with employers like Sanford Health, Monument Health, and Sanford Bismarck hiring at every experience level. Find a role that fits below and apply directly.
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Job Title: Laboratory Technician
Reports To: The Laboratory Manager
Job Summary:
A Laboratory Technician (Tech) is a bench chemistry associate whose main responsibility is to perform routine operations within a laboratory setting. This includes preparing reagents, cleaning glassware, organizing and sorting supplies, and logging in samples. The Tech may also be specialized in one type of analysis for the purposes of improving laboratory workflow. The Tech is responsible for following all documented procedures, recording all laboratory notes, and elevating technical issues to the laboratory manager.
Duties / Responsibilities:
- Ensure that all samples received by the laboratory are logged in according to the appropriate procedure including labeling, logging, etc.
- Maintain a clean and organized lab space
- Prepare reagents at the direction of the Laboratory Manager
- Perform a specific analysis, or portion of analysis, at the direction of the Laboratory Manager
- Report non-conformances to the QAM and Laboratory Manager
Pay Rate:
- Starts at $18/hour DOE
Required Skills and Abilities:
- General familiarity with laboratory safety. Previous laboratory experience preferred.
- Ability to follow written or verbal instructions
- Intermediate skill level (or above) in Microsoft Word, Excel, and Outlook.
- Professional appearance and behavior
Education / Experience:
- HS Diploma or GED equivalent. Associates Degree or higher in a physical science preferred.
Physical Requirements:
- Must be able to meet the physical demands of a typical laboratory environment
- Sitting/standing, reaching overhead cabinets
- Possible light lifting
Key Benefits Include:
- Medical, Dental, and Vision Insurance
- Flexible Spending Accounts
- 401(K) Plan with Competitive Match
- Continuing Education and Tuition Assistance
- Employer-Sponsored Disability Benefits
- Life Insurance
- Employee Assistance Program (EAP)
- Paid Time Off (PTO), Paid Holidays, & Bonus Floating Holiday (if hired before July 1st)
- Profit Sharing or Individual Bonus Programs
- Referral Program
- Per Diem & Paid Travel
- Employee Discount Hub
EEO Commitment: We are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, national origin, ethnicity, sex, pregnancy, sexual orientation, gender identity/expression, including transgender identity, religion, disability, age, genetics, active military or veteran status and any other characteristics protected under applicable federal or state law.
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.
See All 38 Laboratory Jobs in South Dakota
Find roles in South Dakota that match your experience and apply in just a few clicks.
Find Laboratory JobsLaboratory Jobs by City in South Dakota
Where South Dakota roles are concentrated, by current openings.
Laboratory Job Market in South Dakota
A snapshot from current South Dakota openings, updated as new roles post.
Who's Hiring
- Sanford Health15

- Monument Health5

- Sanford Bismarck4

- Sioux Center Health4

- SGS3

Top Industries Hiring
- Healthcare & Medical Services27
- Medical Devices5
- Non-Profit & Social Services4
- Agriculture & Farming1
- Animal Care & Pet Services1
What South Dakota Employers Look For
The qualifications that appear most often in laboratory jobs across South Dakota.
- Bachelor's degree in biology, chemistry, medical laboratory science, or a related field
- Hands-on experience with techniques such as PCR, ELISA, microscopy, or chromatography
- Familiarity with laboratory information systems and data documentation practices
- Knowledge of GLP, GMP, or CLIA regulatory standards depending on the lab setting
- ASCP, AMT, or equivalent certification for clinical or diagnostic laboratory roles
- Ability to maintain accurate records, follow standard operating procedures, and work safely with biological or chemical samples
Laboratory Jobs in South Dakota: Frequently Asked Questions
How many laboratory jobs are there in South Dakota?
There are 38+ laboratory openings in South Dakota on Migrate Mate as of June 2026, with the most roles in Sioux Falls, Rapid City, and North Sioux City. New positions post regularly as employers across South Dakota hire.
Which South Dakota cities have the most laboratory jobs?
Sioux Falls, Rapid City, and North Sioux City have the most laboratory openings in South Dakota right now, with additional roles spread across smaller metros statewide.
Which companies hire laboratorys in South Dakota?
Employers hiring laboratorys in South Dakota include Sanford Health, Monument Health, and Sanford Bismarck, based on current listings on Migrate Mate as of June 2026.
Are there remote laboratory jobs in South Dakota?
Yes. About 3% of laboratory openings tied to South Dakota are remote or hybrid as of June 2026. The rest are on-site roles based in South Dakota metros.
How do I apply for laboratory jobs in South Dakota?
You can apply to laboratory jobs in South Dakota directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Dakota location, then apply to each one that fits.
See All 38 Laboratory Jobs in South Dakota
Find roles in South Dakota that match your experience and apply in just a few clicks.
Find Laboratory Jobs