Senior Level Lead Research Scientist Jobs

Senior level lead research scientist jobs place experienced scientists in charge of research direction, experimental strategy, and the teams or cross-functional projects that drive discovery forward. Openings are concentrated in Technology & Software, Science & Research, and Education, with a mix of on-site, remote, and hybrid settings, and employers like AbbVie, NVIDIA, and Meta hiring at this level now.

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Overview

Open roles66
Top stateCalifornia
Top employerAbbVie
Top citySan Francisco, CA
Work type73% On-site
Top industryTechnology

Showing 5 of 66+ Senior Level Lead Research Scientist jobs

AI Research Scientist
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AI Research Scientist
Apple
Seattle, Washington
Software Engineering
Data Science & Analytics
Data Engineering
AI (Artificial Intelligence)
ML (Machine Learning)
Data Science
$205k - $309k/yr
On-Site
Master's
10,000+

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Senior Research Scientist
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Added 3d ago
Senior Research Scientist
MD Anderson Cancer Center
Houston, Texas
Laboratory Research
Biotech & Life Sciences
Clinical Trials & Medical Research
Clinical Trials
$79k - $118k/yr
Hybrid
Doctorate
10,000+

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Principal Research Scientist I, Biologics CMC Developability Modeling
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Principal Research Scientist I, Biologics CMC Developability Modeling
AbbVie
North Chicago, Illinois
IT Support
Project Management
Technical Program Management
$125k - $237k/yr
Hybrid
Master's degree in chemistry
10,000+

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Research Scientist
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Added 3d ago
Research Scientist
Thermo Fisher Scientific
Collegeville, Pennsylvania
Laboratory Research
Biotech & Life Sciences
Clinical Trials & Medical Research
Environmental & Physical Sciences
Clinical Trials
Environmental Science
On-Site
Bachelor's
10,000+

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Principal Research Scientist I
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Added 1w ago
Principal Research Scientist I
AbbVie
North Chicago, Illinois
Data Science & Analytics
Software Engineering
Healthcare Administration
Laboratory Research
Data Science
$125k - $237k/yr
On-Site
Doctorate
10,000+

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Senior Level Lead Research Scientist Job Market

Who's Hiring

AbbVie7 open roles
NVIDIA4 open roles
Meta3 open roles

Top Industries Hiring

  • Technology & Software29
  • Science & Research8
  • Education7
  • Biotechnology & Pharmaceuticals6
  • Electronics & Hardware3

Senior Level Lead Research Scientist Jobs: Frequently Asked Questions

How do I get a senior level lead research scientist job?

Employers at this level look for candidates who have independently driven research programs from hypothesis through publication or application, not just contributed to them. A strong portfolio of first-author work, demonstrated mentorship of junior scientists, and evidence of cross-functional collaboration with engineering or product teams will differentiate you. Tailoring your materials to show ownership of outcomes, not just participation, is what moves applications forward at the senior level.

Which companies hire senior level lead research scientists?

Companies hiring senior level lead research scientists right now include AbbVie, NVIDIA, and Meta, based on current listings on Migrate Mate as of November 2026. Hiring at this level tends to concentrate among pharmaceutical and biotech firms, technology companies with dedicated R&D divisions, and large industrial or defense organizations running sustained research programs.

Are there remote senior level lead research scientist jobs?

Yes, though availability depends heavily on the nature of the research. About 27% of senior level lead research scientist openings are remote or hybrid as of November 2026, with computational, data science, and modeling-focused roles offering the most flexibility. Lab-based or wet-science positions typically require on-site presence, so filtering by work setting early in your search saves time.

What makes a lead research scientist role senior level?

Senior level roles are defined by scope and ownership. Where mid-level scientists execute within defined projects, senior lead research scientists set the research agenda, make architectural decisions about methodology, and are accountable for program outcomes. They mentor junior and mid-level scientists, interface with leadership to align research priorities with organizational goals, and often represent the team in cross-functional or external scientific discussions.

Which industries hire the most senior level lead research scientists?

Senior level lead research scientist roles concentrate in Technology & Software, Science & Research, and Education, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring at this level because they sustain large internal R&D investments and need experienced scientists who can lead long-horizon research programs with minimal oversight.