NP Jobs in St. Louis, MO

NP jobs in St. Louis are concentrated in the Cortex Innovation Community, the Medical Center corridor near Forest Park, and the downtown BJC HealthCare campus, with strong demand in primary care, acute care, and behavioral health. Employers actively hiring include BJC HealthCare, Mercy, and Esse Health. See the openings below and apply to the ones that match your experience.

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Overview

Open roles94
Top employerBJC HealthCare
Work type100% On-site
Top credentialDoctoral degree
Companies hiring8

Showing 5 of 94+ NP jobs

Physician Assistant or Nurse Practitioner - PRN
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Added 4d ago
Physician Assistant or Nurse Practitioner - PRN
GoHealth Urgent Care
St. Louis, Missouri
Allied Health
Healthcare Administration
Nursing
Master's degree
501-1,000

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Advanced Practice Provider - Nurse Practitioner or Physician Assistant
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Added 4d ago
Advanced Practice Provider - Nurse Practitioner or Physician Assistant
Shriners Children's
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
On-Site
PALS Certification
5,001-10,000

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Nurse Practitioner, HouseCalls - Missouri Statewide Traveler
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Added 5d ago
Nurse Practitioner, HouseCalls - Missouri Statewide Traveler
Optum
St. Louis, Missouri
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing
$110k - $164k/yr
10,000+

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Nurse Practitioner or Physician Assistant – Emergency Department, Mercy Hospital South
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Added 5d ago
Nurse Practitioner or Physician Assistant – Emergency Department, Mercy Hospital South
Mercy
St. Louis, Missouri
Allied Health
Clinical Support
Healthcare Administration
10,000+

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Nurse Practitioner or Physician Assistant for Hospitalist at Missouri Baptist Medical Center, 7on/7off, Days
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Added 6d ago
Nurse Practitioner or Physician Assistant for Hospitalist at Missouri Baptist Medical Center, 7on/7off, Days
BJC HealthCare
St. Louis, Missouri
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing
$126k.6 - $171k.59/yr
Doctoral degree
10,000+

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NP Job Market in St. Louis

Who's Hiring

  • BJC HealthCare27
  • Mercy20
  • Esse Health13
  • Optum7
  • VITAS Healthcare7

NP Jobs in St. Louis: Frequently Asked Questions

How do I get a np job in St. Louis?

Focus your search on St. Louis's dense healthcare corridor stretching from the Washington University Medical Campus through the BJC system and into south county community health centers. Large health systems, federally qualified health centers, and specialty group practices drive the most consistent hiring. Candidates with acute care or primary care experience, a DEA registration, and Missouri prescriptive authority established upfront move faster through screening than those who need to obtain it after hire.

Which companies hire nps in St. Louis?

St. Louis np roles are posted by BJC HealthCare, Mercy, and Esse Health and others right now, based on current listings on Migrate Mate as of October 2026. St. Louis's market is anchored by major academic health systems, multi-site outpatient groups, and an expanding network of urgent care and retail clinic operators spread across the city and St. Louis County.

Are there remote np jobs in St. Louis?

Yes, though remote work is limited for NPs given the hands-on nature of clinical practice. About 0% of np openings tied to St. Louis are remote or hybrid as of October 2026, which typically reflects telehealth roles in behavioral health, chronic disease management, and post-discharge follow-up care. St. Louis-area employers in managed care and insurance utilization review also post fully remote NP positions more consistently than traditional clinic settings.

How can I get a np job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is through nurse residency or NP fellowship programs offered by the larger health systems, which are designed specifically for new graduates building clinical confidence. Federally qualified health centers across north and south St. Louis city also hire new-to-practice NPs for primary care roles with structured mentorship. Completing clinical rotations with a St. Louis employer and expressing interest in full-time placement before graduation is a common way candidates convert to hired status ahead of the open market.

See All 94 NP Jobs in St. Louis

Find roles in St. Louis that match your experience and apply in just a few clicks.

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