Nurse Practitioner Jobs in Indianapolis, IN

Nurse Practitioner jobs in Indianapolis are concentrated in the Meridian-Kessler medical corridor, the IUPUI campus area, and the downtown Indiana University Health complex, with strong demand across primary care, urgent care, and hospital-based specialty practices. Employers actively hiring include Indiana University Health, Ascension, and HarmonyCares. See the openings below and apply to the ones that match your experience.

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Overview

Open roles87
Top employerIndiana University Health
Work type50% Remote
Top credentialMaster's degree
Companies hiring10

Showing 5 of 87+ Nurse Practitioner jobs

Indiana University Health
Nurse Practitioner or Physician Assistant - Orthopedic Trauma-PRN (Methodist Hospital)
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Indiana University Health
Added 1d ago
Nurse Practitioner or Physician Assistant - Orthopedic Trauma-PRN (Methodist Hospital)
Indiana University Health
Indianapolis, Indiana
Allied Health
Clinical Support
Healthcare Administration
10,000+

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Indiana University Health
Nurse Practitioner or Physician Assistant - Adult Psychiatry- Post-Stroke Depression (Goodman Hall)
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Indiana University Health
Added 1d ago
Nurse Practitioner or Physician Assistant - Adult Psychiatry- Post-Stroke Depression (Goodman Hall)
Indiana University Health
Indianapolis, Indiana
Healthcare Administration
Patient Services & Wellbeing
Physicians
10,000+

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Indiana University Health
Nurse Practitioner or Physician Assistant - Psychiatry (Goodman Hall)
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Indiana University Health
Added 1d ago
Nurse Practitioner or Physician Assistant - Psychiatry (Goodman Hall)
Indiana University Health
Indianapolis, Indiana
Allied Health
Clinical Support
Healthcare Administration
10,000+

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M
Family Nurse Practitioner
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M
Added 1d ago
Family Nurse Practitioner
Meridian Park Wellness Spa
Indianapolis, Indiana
Healthcare Administration
Patient Services & Wellbeing
Physicians
On-Site
BLS Certification

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Ascension
Psychiatry NP / PA
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Ascension
Added 1d ago
Psychiatry NP / PA
Ascension
Indianapolis, Indiana
Customer Service
Healthcare Administration
Human Resources
BLS Certification
10,000+

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See All 87 Nurse Practitioner Jobs in Indianapolis

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Nurse Practitioner Job Market in Indianapolis

Who's Hiring

  • Indiana University Health
    Indiana University Health35
  • Ascension
    Ascension6
  • HarmonyCares
    HarmonyCares6
  • Legion Health
    Legion Health6
  • State of Indiana
    State of Indiana6

Nurse Practitioner Jobs in Indianapolis: Frequently Asked Questions

How do I get a nurse practitioner job in Indianapolis?

Focus your search on the dense healthcare corridor along North Meridian Street, the IUPUI-adjacent research and outpatient clinics, and the expanding urgent care networks on the northeast and northwest sides of the city. Large integrated health systems, federally qualified health centers serving underserved neighborhoods, and the growing network of retail and employer-based clinics all hire actively. Candidates with a specialty certification in family practice or psychiatric mental health have a clear edge in Indianapolis right now.

Which companies hire nurse practitioners in Indianapolis?

Companies currently hiring nurse practitioners in Indianapolis include Indiana University Health, Ascension, and HarmonyCares, per current listings on Migrate Mate as of August 2026. Indianapolis employers range from large academic medical centers and regional hospital systems to independent urgent care chains and community health organizations serving the city's diverse residential neighborhoods.

Are there remote nurse practitioner jobs in Indianapolis?

Yes, though remote opportunities are limited by nature since most nurse practitioner roles require direct patient care and on-site clinical work. About 75% of nurse practitioner openings tied to Indianapolis are remote or hybrid as of August 2026, concentrated in telehealth platforms, care management, and utilization review roles. Indianapolis-based insurers and managed care organizations are the most consistent source of remote positions locally.

How can I get a nurse practitioner job in Indianapolis with little or no experience?

The most realistic entry path is through a nurse residency or new-graduate NP fellowship, with IU Health and Eskenazi Health running structured programs designed for candidates without post-graduation clinical hours. Community health centers across Indianapolis, including those serving the near-eastside and southside, often hire new graduates for primary care roles where mentorship is built into the practice model. A family practice or internal medicine focus and demonstrated clinical hours from Indianapolis-area preceptorships strengthen any application significantly.

See All 87 Nurse Practitioner Jobs in Indianapolis

Find roles in Indianapolis that match your experience and apply in just a few clicks.

Find Nurse Practitioner Jobs