Nurse Practitioner Jobs in Indianapolis, IN
Nurse Practitioner jobs in Indianapolis are concentrated in the Meridian-Kessler medical corridor, the IUPUI campus area, and the downtown Indiana University Health complex, with strong demand across primary care, urgent care, and hospital-based specialty practices. Employers actively hiring include Indiana University Health, Ascension, and HarmonyCares. See the openings below and apply to the ones that match your experience.
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IU Health Medical Group is hiring! We are seeking a Nurse Practitioner or Physician Assistant to join our Orthopedic Trauma team at Methodist Hospital in Indianapolis, IN!
Position Details:
- PRN
- Day Shift
- Shifts available based coverage needs.
- Minimum of 8 hours every 6 weeks
- No call
- 80% Inpatient and 20% Outpatient
- Team includes 8 physicians and 16 advanced practice providers
Key Responsibilities:
- Orthopedic Trauma consults
- Inpatient Rounding
Procedures:
- Fracture/dislocation reductions
- Application of splints
- First Assist in the OR
- Joint Injections
- Joint Aspirations
- Wound Vac application and changes
- Traction Application
Qualifications:
- ACNP, AGNP, FNP or PA certification required
- At least 1 year of APP experience required
- APP experience in orthopedics preferred
Compensation Details:
- We offer a strong compensation model
- Comprehensive benefits package includes group insurance (health, dental, life, disability), 401k with company match, PTO, relocation assistance and occurrence-based malpractice insurance coverage
See how you can thrive, right here at Indiana University Health
Community Description
Indianapolis, Indiana, the 17th largest U.S. city, is a sophisticated city blending charm and culture with a wonderful balance of business and leisure. Residents of this dynamic city enjoy:
- Leading educational system and top-ranked universities, paired with a diverse population
- Vibrant downtown offering arts, theaters, world-class museums, zoo, concerts and memorials
- Named to U.S. News & World Report's 2023-2024 list of the best places to live in the United States
- Top ranked international airport: "Best Airport in North America" twelve consecutive years
- Ranked by Niche in 2023 as one of the most diverse counties in America, as well as one of the best cities to live in and buy a house in the country
- Historic neighborhoods with surrounding cultural districts and low cost of living
- Outdoor recreation includes golfing, boating and unique parks
- Home of the Colts (NFL), Fever (WNBA), Pacers (NBA), Indians (MiLB), Indianapolis 500 (IndyCar) and the nation's largest half marathon
- Close proximity to Chicago, St. Louis, Louisville, and Cincinnati
Healthcare System/Hospital Description
IU Health Methodist Hospital is a regional healthcare leader through its commitment to excellence, accessibility and preeminence. Part of the IU Health Adult Academic Health Center, it is currently ranked by U.S. News & World Report as the top hospital in the state of Indiana, with 13 procedures/conditions rated as high performing.
With 1,000 beds, IU Health Methodist Hospital is a large tertiary referral center with over 130 ICU beds. It serves as the largest trauma center in Indianapolis, as well as a highly subspecialized center for cardiovascular surgery, thoracic surgery, neurosurgery, lung transplantation, and neurocritical care.
IU Health is building a new downtown hospital and campus, which will consolidate operations of the adjacent IU Health Methodist and University Hospitals. Construction for the new hospital is well underway and set to open in late 2027. It will feature three 16-story towers with 864 beds. IU School of Medicine is also constructing a medical education and research building directly east of the new hospital.
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Find Nurse Practitioner JobsNurse Practitioner Job Market in Indianapolis
Who's Hiring
- Indiana University Health35

- Ascension6

- HarmonyCares6

- Legion Health6

- State of Indiana6

Nurse Practitioner Jobs in Indianapolis: Frequently Asked Questions
How do I get a nurse practitioner job in Indianapolis?
Focus your search on the dense healthcare corridor along North Meridian Street, the IUPUI-adjacent research and outpatient clinics, and the expanding urgent care networks on the northeast and northwest sides of the city. Large integrated health systems, federally qualified health centers serving underserved neighborhoods, and the growing network of retail and employer-based clinics all hire actively. Candidates with a specialty certification in family practice or psychiatric mental health have a clear edge in Indianapolis right now.
Which companies hire nurse practitioners in Indianapolis?
Companies currently hiring nurse practitioners in Indianapolis include Indiana University Health, Ascension, and HarmonyCares, per current listings on Migrate Mate as of August 2026. Indianapolis employers range from large academic medical centers and regional hospital systems to independent urgent care chains and community health organizations serving the city's diverse residential neighborhoods.
Are there remote nurse practitioner jobs in Indianapolis?
Yes, though remote opportunities are limited by nature since most nurse practitioner roles require direct patient care and on-site clinical work. About 75% of nurse practitioner openings tied to Indianapolis are remote or hybrid as of August 2026, concentrated in telehealth platforms, care management, and utilization review roles. Indianapolis-based insurers and managed care organizations are the most consistent source of remote positions locally.
How can I get a nurse practitioner job in Indianapolis with little or no experience?
The most realistic entry path is through a nurse residency or new-graduate NP fellowship, with IU Health and Eskenazi Health running structured programs designed for candidates without post-graduation clinical hours. Community health centers across Indianapolis, including those serving the near-eastside and southside, often hire new graduates for primary care roles where mentorship is built into the practice model. A family practice or internal medicine focus and demonstrated clinical hours from Indianapolis-area preceptorships strengthen any application significantly.
See All 87 Nurse Practitioner Jobs in Indianapolis
Find roles in Indianapolis that match your experience and apply in just a few clicks.
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