OPT Laboratory Supervisor Jobs
Laboratory Supervisor roles are a strong fit for F-1 OPT students with degrees in biology, chemistry, biochemistry, or a related science field. Most positions qualify as STEM-designated roles, giving you up to 36 months of work authorization. Employers in research, biotech, and clinical settings regularly hire supervisors through OPT.
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Get Access To All JobsLC-MS/MS Toxicology Laboratory Supervisor
Rocky Mountain Laboratories – Draper, Utah
About us
Rocky Mountain Laboratories is a clinical laboratory providing comprehensive laboratory services. We are dedicated to delivering accurate and timely diagnostic information and are committed to improving healthcare outcomes through cutting-edge technology and a customer-focused approach.
Position
Rocky Mountain Laboratories is seeking an experienced Clinical Toxicology Laboratory Supervisor with hands-on Agilent LC-MS/MS expertise and method development experience to lead our toxicology department in Draper, Utah, part of the Salt Lake City metro area.
This is a working supervisor role in a CLIA-certified, high-complexity toxicology laboratory. You'll combine bench-level technical work — including LC-MS/MS method development and validation, instrument operation, and data review — with day-to-day departmental leadership: staff oversight, SOP development, QC program management, and regulatory compliance. You'll serve as the primary technical and operational lead for the toxicology department and act as department representative in the absence of the Lab Manager.
Job Type: Full-time, W2
Schedule: Monday–Friday | 8:00 a.m.–4:30 p.m. | Day shift
Salary: $130,000–$150,000 annually
Location: Draper, UT (Salt Lake City metro) — reliable commute or relocation required before start date
Start Date: As soon as the right candidate is found
Responsibilities:
- Supervise daily toxicology laboratory operations to ensure accurate, timely, and compliant high-complexity testing
- Operate, calibrate, maintain, troubleshoot, and optimize Agilent 6460 triple quadrupole LC-MS/MS instrumentation and related platforms
- Develop, validate, and implement new analytical methods for clinical toxicology panels including drugs of abuse (DOA), pain management, and therapeutic drug monitoring (TDM)
- Lead method verification, troubleshooting, and continuous optimization of existing assays
- Oversee sample preparation workflows for urine and oral fluid specimens
- Develop, implement, and maintain Standard Operating Procedures (SOPs) for validations, clinical testing, and regulatory compliance
- Review, interpret, and authorize release of patient test results using Agilent MassHunter and other laboratory software in accordance with laboratory policies and CLIA standards
- Manage quality control (QC) and quality assurance (QA) programs; investigate out-of-range results and deviations; implement and document corrective actions
- Monitor workflow, prioritize testing queues, and allocate staff resources to meet turnaround time expectations
- Train, mentor, and evaluate laboratory staff; develop and administer competency assessments and provide ongoing technical guidance
- Serve as CLIA General Supervisor for the toxicology department, ensuring full compliance with high-complexity testing standards, OSHA safety requirements, and other applicable regulations
- Support internal inspections, CAP accreditation activities, audits, and regulatory readiness
- Collaborate cross-functionally with Chemistry, Molecular, Client Services, and other departments to resolve operational and testing issues
- Drive continuous improvement initiatives related to workflow efficiency, quality outcomes, and cost reduction
- Ensure proper handling, storage, and disposal of hazardous and biological materials
- Serve as acting department leader in the absence of the Lab Manager
- Perform other duties as assigned
Required Qualifications:
- Bachelor of Science or higher in chemistry, biology, clinical laboratory science, medical laboratory science, or a closely related field
- Minimum 2 years of documented hands-on clinical toxicology experience in a CLIA-certified high-complexity laboratory, including experience with drugs of abuse (DOA), pain management panels, or therapeutic drug monitoring (TDM)
- Recent hands-on experience operating, maintaining, and troubleshooting Agilent 6460 triple quadrupole LC-MS/MS or equivalent Agilent 6400-series instrumentation, including proficiency with Agilent MassHunter for data acquisition, analysis, and reporting
- Documented experience in LC-MS/MS method development and validation in a clinical or regulated laboratory setting
- Proficiency with sample preparation techniques, including dilute-and-shoot, solid-phase extraction (SPE), and liquid-liquid extraction (LLE)
- Strong knowledge of quality assurance, quality control principles, and corrective action processes
- Demonstrated knowledge of CLIA high-complexity testing regulations, OSHA safety requirements, and regulatory compliance
- Excellent organizational, analytical, and problem-solving skills
- Strong written and verbal communication skills
- Ability to manage multiple priorities while maintaining accuracy and compliance
Preferred Qualifications:
- 3–5+ years of clinical toxicology laboratory experience, including at least 1 year in a supervisory, lead, or certifying scientist capacity
- Experience developing or delivering competency assessments for laboratory staff
- Experience with Beckman Coulter AU 480/680 or equivalent Beckman Coulter AU-series chemistry analyzers (e.g., AU400, AU5800)
- Experience with additional LC-MS/MS platforms (e.g., SCIEX, Shimadzu, Thermo Fisher)
- Experience supporting CAP accreditation, laboratory audits, and regulatory inspections
- Familiarity with Laboratory Information Systems (LIS) and electronic reporting workflows
- Ability to design and deliver technical training programs for laboratory staff
- Experience with high-throughput batch processing workflows in a clinical toxicology environment
- ASCP MLS(ASCP), AMT MT, NRCC, or other relevant certification
- Master's degree in chemistry, toxicology, clinical laboratory science, or a related field
Benefits for full-time W2 Team Members:
Benefits begin 60 days after the first full month of full-time employment.
- Health, Dental, and Vision Insurance
- Paid Time Off (21 days annually for full-time team members)
- 7 Paid Holidays
- 401(k) with 50% Company Match up to 6%
- Health Savings Account (HSA)
- Short-Term & Long-Term Disability (RML covers 60% of STD premium)
- Voluntary Life and AD&D Insurance
- 100% Company-Funded Employee Assistance Program (EAP)
Application Deadline: Applications are reviewed on a rolling basis, and the position may be filled before any stated deadline
If you meet the above qualifications and are interested in joining our team, please submit your resume for consideration. We look forward to hearing from you!
At Rocky Mountain Laboratories, we prioritize the care and well-being of our team members.
Equal Opportunity Employer Statement
Rocky Mountain Laboratories is an Equal Opportunity Employer committed to diversity in its workforce. We comply with all applicable federal and state laws and prohibit discrimination based on race, ethnicity, religion, color, national origin, sex, age, sexual orientation, gender identity or expression, veteran status, disability, or genetic information. We also comply with the Americans with Disabilities Act (ADA) and provide reasonable accommodations to qualified individuals with disabilities.
Pre-Employment Notice & E-Verify
Rocky Mountain Laboratories participates in E-Verify.
Employment is contingent upon successful completion of a background check and other pre-employment screenings, as required.
Employment with Rocky Mountain Laboratories is at-will. This means either the Team Member or the company may end the employment relationship at any time, with or without cause or notice, in accordance with applicable laws. Nothing in this posting or in future communications alters that relationship.
While we appreciate interest from staffing agencies, Rocky Mountain Laboratories does not currently partner with external agencies. Resumes submitted unsolicited will not be considered, and no fees will be paid.
LC-MS/MS Toxicology Laboratory Supervisor
Rocky Mountain Laboratories – Draper, Utah
About us
Rocky Mountain Laboratories is a clinical laboratory providing comprehensive laboratory services. We are dedicated to delivering accurate and timely diagnostic information and are committed to improving healthcare outcomes through cutting-edge technology and a customer-focused approach.
Position
Rocky Mountain Laboratories is seeking an experienced Clinical Toxicology Laboratory Supervisor with hands-on Agilent LC-MS/MS expertise and method development experience to lead our toxicology department in Draper, Utah, part of the Salt Lake City metro area.
This is a working supervisor role in a CLIA-certified, high-complexity toxicology laboratory. You'll combine bench-level technical work — including LC-MS/MS method development and validation, instrument operation, and data review — with day-to-day departmental leadership: staff oversight, SOP development, QC program management, and regulatory compliance. You'll serve as the primary technical and operational lead for the toxicology department and act as department representative in the absence of the Lab Manager.
Job Type: Full-time, W2
Schedule: Monday–Friday | 8:00 a.m.–4:30 p.m. | Day shift
Salary: $130,000–$150,000 annually
Location: Draper, UT (Salt Lake City metro) — reliable commute or relocation required before start date
Start Date: As soon as the right candidate is found
Responsibilities:
- Supervise daily toxicology laboratory operations to ensure accurate, timely, and compliant high-complexity testing
- Operate, calibrate, maintain, troubleshoot, and optimize Agilent 6460 triple quadrupole LC-MS/MS instrumentation and related platforms
- Develop, validate, and implement new analytical methods for clinical toxicology panels including drugs of abuse (DOA), pain management, and therapeutic drug monitoring (TDM)
- Lead method verification, troubleshooting, and continuous optimization of existing assays
- Oversee sample preparation workflows for urine and oral fluid specimens
- Develop, implement, and maintain Standard Operating Procedures (SOPs) for validations, clinical testing, and regulatory compliance
- Review, interpret, and authorize release of patient test results using Agilent MassHunter and other laboratory software in accordance with laboratory policies and CLIA standards
- Manage quality control (QC) and quality assurance (QA) programs; investigate out-of-range results and deviations; implement and document corrective actions
- Monitor workflow, prioritize testing queues, and allocate staff resources to meet turnaround time expectations
- Train, mentor, and evaluate laboratory staff; develop and administer competency assessments and provide ongoing technical guidance
- Serve as CLIA General Supervisor for the toxicology department, ensuring full compliance with high-complexity testing standards, OSHA safety requirements, and other applicable regulations
- Support internal inspections, CAP accreditation activities, audits, and regulatory readiness
- Collaborate cross-functionally with Chemistry, Molecular, Client Services, and other departments to resolve operational and testing issues
- Drive continuous improvement initiatives related to workflow efficiency, quality outcomes, and cost reduction
- Ensure proper handling, storage, and disposal of hazardous and biological materials
- Serve as acting department leader in the absence of the Lab Manager
- Perform other duties as assigned
Required Qualifications:
- Bachelor of Science or higher in chemistry, biology, clinical laboratory science, medical laboratory science, or a closely related field
- Minimum 2 years of documented hands-on clinical toxicology experience in a CLIA-certified high-complexity laboratory, including experience with drugs of abuse (DOA), pain management panels, or therapeutic drug monitoring (TDM)
- Recent hands-on experience operating, maintaining, and troubleshooting Agilent 6460 triple quadrupole LC-MS/MS or equivalent Agilent 6400-series instrumentation, including proficiency with Agilent MassHunter for data acquisition, analysis, and reporting
- Documented experience in LC-MS/MS method development and validation in a clinical or regulated laboratory setting
- Proficiency with sample preparation techniques, including dilute-and-shoot, solid-phase extraction (SPE), and liquid-liquid extraction (LLE)
- Strong knowledge of quality assurance, quality control principles, and corrective action processes
- Demonstrated knowledge of CLIA high-complexity testing regulations, OSHA safety requirements, and regulatory compliance
- Excellent organizational, analytical, and problem-solving skills
- Strong written and verbal communication skills
- Ability to manage multiple priorities while maintaining accuracy and compliance
Preferred Qualifications:
- 3–5+ years of clinical toxicology laboratory experience, including at least 1 year in a supervisory, lead, or certifying scientist capacity
- Experience developing or delivering competency assessments for laboratory staff
- Experience with Beckman Coulter AU 480/680 or equivalent Beckman Coulter AU-series chemistry analyzers (e.g., AU400, AU5800)
- Experience with additional LC-MS/MS platforms (e.g., SCIEX, Shimadzu, Thermo Fisher)
- Experience supporting CAP accreditation, laboratory audits, and regulatory inspections
- Familiarity with Laboratory Information Systems (LIS) and electronic reporting workflows
- Ability to design and deliver technical training programs for laboratory staff
- Experience with high-throughput batch processing workflows in a clinical toxicology environment
- ASCP MLS(ASCP), AMT MT, NRCC, or other relevant certification
- Master's degree in chemistry, toxicology, clinical laboratory science, or a related field
Benefits for full-time W2 Team Members:
Benefits begin 60 days after the first full month of full-time employment.
- Health, Dental, and Vision Insurance
- Paid Time Off (21 days annually for full-time team members)
- 7 Paid Holidays
- 401(k) with 50% Company Match up to 6%
- Health Savings Account (HSA)
- Short-Term & Long-Term Disability (RML covers 60% of STD premium)
- Voluntary Life and AD&D Insurance
- 100% Company-Funded Employee Assistance Program (EAP)
Application Deadline: Applications are reviewed on a rolling basis, and the position may be filled before any stated deadline
If you meet the above qualifications and are interested in joining our team, please submit your resume for consideration. We look forward to hearing from you!
At Rocky Mountain Laboratories, we prioritize the care and well-being of our team members.
Equal Opportunity Employer Statement
Rocky Mountain Laboratories is an Equal Opportunity Employer committed to diversity in its workforce. We comply with all applicable federal and state laws and prohibit discrimination based on race, ethnicity, religion, color, national origin, sex, age, sexual orientation, gender identity or expression, veteran status, disability, or genetic information. We also comply with the Americans with Disabilities Act (ADA) and provide reasonable accommodations to qualified individuals with disabilities.
Pre-Employment Notice & E-Verify
Rocky Mountain Laboratories participates in E-Verify.
Employment is contingent upon successful completion of a background check and other pre-employment screenings, as required.
Employment with Rocky Mountain Laboratories is at-will. This means either the Team Member or the company may end the employment relationship at any time, with or without cause or notice, in accordance with applicable laws. Nothing in this posting or in future communications alters that relationship.
While we appreciate interest from staffing agencies, Rocky Mountain Laboratories does not currently partner with external agencies. Resumes submitted unsolicited will not be considered, and no fees will be paid.
See all 99+ OPT Laboratory Supervisor Jobs
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Get Access To All JobsTips for Finding OPT Sponsorship in Laboratory Supervisor
Confirm your role qualifies as STEM OPT
Laboratory Supervisor positions typically fall under CIP codes tied to biological sciences, chemistry, or engineering. Verify your degree's CIP code matches a STEM-designated field before applying, so you can claim the full 36-month extension without surprises.
Target employers with an active E-Verify account
STEM OPT extensions require your employer to be enrolled in E-Verify. Ask recruiters directly before accepting an offer. Many biotech firms, university research labs, and hospital systems already participate, making them safer bets for STEM extension eligibility.
Highlight supervisory and compliance experience
Laboratory Supervisor roles demand documented leadership over staff, safety protocols, and regulatory compliance. Emphasize relevant experience with OSHA standards, CAP or CLIA regulations, or quality management systems to differentiate yourself from candidates without oversight backgrounds.
Start H-1B conversations with employers before OPT expires
If long-term sponsorship is your goal, raise H-1B visa sponsorship early in the hiring process. Lab-heavy industries like biotech and pharmaceuticals sponsor H-1B visas regularly. Early alignment prevents last-minute scrambles when your OPT window closes.
Use Migrate Mate to find OPT-friendly lab employers
Not every employer understands OPT or wants to navigate the paperwork. Migrate Mate filters Laboratory Supervisor jobs by sponsorship willingness, saving you time and protecting your visa timeline from employers unlikely to support your work authorization.
Laboratory Supervisor OPT: Frequently Asked Questions
Can I work as a Laboratory Supervisor on F-1 OPT?
Yes, if your degree is in a qualifying field such as biology, chemistry, biochemistry, or a related science discipline. The role must be directly related to your area of study. Laboratory Supervisor positions at research institutions, biotech companies, hospitals, and clinical labs routinely meet this requirement, but you should confirm the connection with your DSO before accepting an offer.
Does a Laboratory Supervisor role qualify for the STEM OPT extension?
It typically does, provided your degree falls under a STEM-designated CIP code and your employer is enrolled in E-Verify. Laboratory supervision in fields like biological sciences, chemical engineering, or clinical laboratory science commonly qualifies. Your DSO will verify the CIP code on your I-20 and confirm eligibility before filing the STEM extension application with USCIS.
What industries hire Laboratory Supervisors who are on OPT?
Biotech and pharmaceutical companies, university and government research labs, hospital clinical laboratories, environmental testing firms, and food and beverage quality labs are among the most active hirers. Many of these sectors have established HR processes for OPT candidates and are familiar with E-Verify requirements. Browse current openings on Migrate Mate to find employers already open to OPT work authorization.
What certifications strengthen a Laboratory Supervisor application for OPT students?
Certifications in laboratory management, safety, or quality systems add measurable weight to an application. Credentials such as the American Society for Clinical Pathology's MLS certification, ISO 9001 familiarity, or OSHA 30-hour training demonstrate readiness for supervisory responsibility. Employers subject to CAP or CLIA accreditation especially value candidates who understand regulatory compliance from day one.
Can a Laboratory Supervisor job lead to H-1B sponsorship after OPT?
Yes, and this role is well-positioned for H-1B sponsorship. Laboratory Supervisor positions generally qualify as specialty occupations requiring at least a bachelor's degree in a specific scientific field, which satisfies H-1B requirements. Biotech, pharmaceutical, and clinical employers sponsor H-1B petitions regularly. Discuss sponsorship intentions with the hiring manager before your OPT window closes to ensure the employer is prepared to file in time.