Portfolio Manager Jobs in Morrisville, NC
Portfolio Manager jobs in Morrisville, North Carolina are concentrated in the Research Triangle Park corridor, Perimeter Park, and the Airport Business District, with strong demand across financial services, technology asset management, and life sciences. Employers actively hiring include サイネオス・ヘルス and Thermo Fisher Scientific. Find a role that fits below and apply directly.
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Location: Morrisville, NC, United States
Job ID: 25109761-OTHLOC-1500-2DAL-2DR
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Description
Project Manager II -HIV Research Local Studies & Portfolio Management Support (Sponsor Dedicated/ Remote US)Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape.
Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver – for one another, our customers, and, most importantly, for those in need.
Discover what your 25,000 future colleagues already know:
Why Syneos Health
- We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
- We are committed to building an inclusive culture – where you can authentically be yourself. Central to this is our purpose – Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life.
- We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress.
Job Responsibilities
Clinical Project Manager II – HIV Research (Local Studies & Portfolio Management Support)
Sponsor Dedicated | Remote (US)
Are you a clinical research professional who thrives on organization, portfolio oversight, scientific study management, and ensuring that complex research programs remain on track from concept through publication?
WHY THIS OPPORTUNITY
This is an opportunity to join a highly collaborative Medical Affairs and HIV research organization supporting a diverse portfolio of locally sponsored studies (LSS) focused on HIV treatment and prevention. The team is seeking a detail-oriented project management professional who enjoys bringing structure, visibility, and operational excellence to research portfolios while partnering closely with investigators, scientific leaders, and cross-functional stakeholders.
This role combines study management, governance support, portfolio tracking, publication planning oversight, and executive-level reporting. Success requires someone who can manage multiple competing priorities, maintain exceptional attention to detail, proactively identify risks and delays, and communicate effectively across a broad range of stakeholders.
The ideal candidate is highly organized, process-oriented, and comfortable working across multiple studies simultaneously. You should enjoy building and maintaining tracking systems, developing meaningful portfolio metrics, supporting governance processes, and ensuring leadership has clear visibility into study progress, milestones, risks, and publication activities.
While HIV therapeutic area experience is preferred, candidates with strong clinical research, Medical Affairs, scientific operations, or study management experience in other therapeutic areas will also be considered.
This team values collaboration, accountability, scientific rigor, proactive communication, operational excellence, and continuous improvement.
While remote/home-based candidates may be considered, priority will be given to candidates located in or near Foster City, California, with the ability to work onsite 2–3 days per week.
THE ROLE
As a Clinical Project Manager II – HIV Research, you will provide operational and scientific management support for a portfolio of locally sponsored studies across HIV treatment and prevention programs.
You will serve as a key coordinator responsible for tracking study progress, supporting governance activities, maintaining portfolio visibility, overseeing publication tracking, and ensuring accurate reporting for Medical Affairs leadership. You will partner closely with study teams and stakeholders to ensure studies progress efficiently while maintaining compliance with internal processes and governance expectations.
Success in this role requires someone who can balance multiple projects simultaneously while maintaining a high level of accuracy, organization, and responsiveness.
WHAT YOU WILL DO
- Manage intake, tracking, and ongoing oversight of locally sponsored studies across the HIV treatment and prevention portfolio
- Monitor study milestones, timelines, deliverables, and key performance indicators to ensure visibility and proactive management of study progress
- Identify studies that may be at risk for delays, escalation, or closure and communicate findings to appropriate stakeholders
- Support internal and external protocol review board processes (iPRB/oPRB), including submission coordination, documentation management, tracking, and comment adjudication activities
- Maintain portfolio tracking tools, dashboards, and reporting systems to ensure accurate and timely visibility into study status
- Track publication plans, including abstracts, posters, presentations, and manuscripts across the portfolio
- Develop forecasting reports and publication timelines to support strategic planning activities
- Generate recurring portfolio metrics, study summaries, and status reports for Medical Affairs leadership and key stakeholders
- Assist in the development of executive-level presentations and slide decks supporting Medical Affairs Research (MAR) initiatives and portfolio narratives
- Ensure consistency, completeness, and accuracy across study documentation, tracking systems, and internal reporting tools
- Facilitate communication across study teams and stakeholders to ensure alignment on deliverables, timelines, and expectations
- Support process improvement initiatives that enhance portfolio management, reporting efficiency, and study oversight capabilities
- Maintain awareness of portfolio priorities and proactively identify opportunities to improve visibility, efficiency, and execution
WHO YOU ARE
Required Qualifications
- Bachelor’s degree in Life Sciences, Public Health, Clinical Research, Healthcare, or a related field
- Experience supporting clinical research operations, Medical Affairs research, scientific programs, study management, or project management activities
- Strong experience managing multiple projects, timelines, deliverables, and competing priorities simultaneously
- Experience maintaining study trackers, dashboards, reporting tools, or portfolio management systems
- Strong organizational skills with exceptional attention to detail and follow-through
- Demonstrated ability to identify risks, gaps, and delays proactively while driving resolution activities
- Strong communication and stakeholder management skills with the ability to work effectively across cross-functional teams
- Advanced proficiency with Microsoft PowerPoint, Excel, and other reporting or document management tools
- Ability to synthesize complex information into concise reports, summaries, and executive-level presentations
- Strong analytical, problem-solving, and prioritization capabilities
Preferred Qualifications
- Advanced degree in Life Sciences, Public Health, Clinical Research, Epidemiology, or a related discipline
- Experience supporting Medical Affairs research programs
- Experience with locally sponsored studies, investigator-sponsored studies, or research grant-funded studies
- Familiarity with governance processes, protocol review boards, or scientific review committees
- Experience supporting publication planning, tracking, and forecasting activities
- HIV therapeutic area experience strongly preferred
- Experience working within pharmaceutical, biotechnology, CRO, or sponsor-dedicated environments
- Experience creating portfolio dashboards, operational metrics, and executive-level reporting materials
WHAT MAKES THIS OPPORTUNITY DIFFERENT
- Opportunity to support innovative HIV treatment and prevention research that contributes to meaningful scientific advancement and patient outcomes
- Highly visible role with direct exposure to Medical Affairs leadership and strategic portfolio initiatives
- Blend of study management, portfolio oversight, governance support, and publication planning responsibilities
- Ability to influence operational excellence and improve visibility across a diverse research portfolio
- Collaborative environment with strong cross-functional partnership and stakeholder engagement
- Opportunity to develop expertise in scientific operations, portfolio management, and Medical Affairs research
- Meaningful role supporting the successful execution, tracking, and communication of important HIV research activities
- Remote flexibility within a sponsor-dedicated environment focused on innovation, quality, and continuous improvement
At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.
Salary Range:
$95,000.00 - $175,700.00The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role.
Get to know Syneos Health
Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.
No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.
http://www.syneoshealth.com
Additional Information
Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.
Summary
Roles within Clinical Project Management job family at the M23 level are responsible for planning, directing, creating, and communicating clinical study timelines. These roles gather input from cross-functional teams to create plans that help the team produce deliverables on schedule. They ensure consistency of clinical study and processes across clinical trials, overseeing and resolving operational aspects of clinical trials in conjunction with project teams and in accordance with standard operating procedures (SOP), good clinical practice (GCP), and specific country regulations. Responsibilities include site and vendor selection, preparing clinical trial budgets, and ensuring studies are conducted within clinical trial protocols. These roles also involve monitoring progress and following up with team members and line managers when issues develop. Additionally, they implement and prepare the clinical development strategy as outlined by the clinical teams and may develop trial recruitment strategies. Impact and Contribution Roles within Clinical Project Management job family at the M23 level significantly impact the success of clinical trials by ensuring that all aspects of the study are conducted efficiently and effectively. By gathering input from cross-functional teams and creating detailed plans, these roles help ensure that deliverables are produced on schedule, contributing to the overall success of the clinical trials. Their oversight of operational aspects of clinical trials ensures consistency and adherence to SOP, GCP, and country regulations, which is crucial for the integrity and reliability of the study results. Additionally, their involvement in site and vendor selection, budget preparation, and monitoring progress helps maintain the smooth operation of clinical trials, ultimately contributing to the advancement of clinical research and development. Core Focus • Planning, directing, creating, and communicating clinical study timelines • Overseeing operational aspects of clinical trials • Ensuring consistency across clinical studies • Adhering to SOP, GCP, and country regulations • Selecting sites and vendors • Preparing clinical trial budgets • Monitoring progress and following up with team members and line managers • Implementing and preparing the clinical development strategy • Developing trial recruitment strategiesSee All 53 Portfolio Manager Jobs in Morrisville
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Who's Hiring
- サイネオス・ヘルス52サ
- Thermo Fisher Scientific1
Top Industries Hiring
- Science & Research1
- Consulting & Professional Services1
Portfolio Manager Jobs in Morrisville: Frequently Asked Questions
How do I get a portfolio manager job in Morrisville?
Focus your search on Morrisville's financial services firms, technology companies managing product or investment portfolios, and the contract research organizations clustered near Research Triangle Park. Roles in the RTP corridor and Perimeter Park tend to be the most active. Candidates with CFA credentials, demonstrated experience in quantitative analysis, or a background in the life sciences or fintech sectors have a measurable edge with Morrisville employers.
Which companies hire portfolio managers in Morrisville?
Companies currently hiring portfolio managers in Morrisville include サイネオス・ヘルス and Thermo Fisher Scientific, per current listings on Migrate Mate as of July 2026. Morrisville's employer mix leans heavily toward technology firms, financial services companies, and contract research organizations, many of which maintain dedicated investment or product portfolio functions.
Are there remote portfolio manager jobs in Morrisville?
Yes, though availability depends on the role type. Analytical and investment-focused portfolio manager positions tend to offer more flexibility than hands-on product or real asset roles. About 0% of portfolio manager openings tied to Morrisville are remote or hybrid as of July 2026, reflecting broader trends in the Research Triangle market. Technology and financial services employers in the area are most likely to post hybrid arrangements.
How can I get a portfolio manager job in Morrisville with little or no experience?
The most realistic entry path in Morrisville is through an analyst or associate role at one of the financial services firms or technology companies near Research Triangle Park, where portfolio support functions often feed into full portfolio manager tracks. Local contract research organizations and fintech firms also hire junior candidates into project or program coordinator roles that develop the same core skills. A CFA Level I candidacy and demonstrated proficiency with portfolio management software strengthen any entry-level application considerably.
Which industries hire the most portfolio managers in Morrisville?
Most portfolio manager openings in Morrisville sit in Science & Research and Consulting & Professional Services, per current listings on Migrate Mate as of July 2026. Morrisville's position adjacent to Research Triangle Park draws a concentration of technology, life sciences, and financial services employers that all rely on portfolio management functions to oversee product lines, investments, or large project portfolios.
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