Principal Engineer Jobs in Palo Alto, CA

Principal Engineer jobs in Palo Alto are concentrated in the Stanford Research Park, downtown University Avenue corridor, and the adjacent Midtown district, where employers in deep tech, enterprise software, semiconductors, and AI infrastructure maintain active engineering teams. Companies hiring right now include JPMorganChase, Pika, and GenBio AI. Find a role that fits below and apply directly.

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Overview

Open roles815+
Top employerJPMorganChase
Work type67% On-site
Companies hiring5

Showing 5 of 815+ Principal Engineer jobs

JPMorganChase
Senior Principal Software Engineer - Fraud Prevention Engineering
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JPMorganChase
New 7h ago
Senior Principal Software Engineer - Fraud Prevention Engineering
JPMorganChase
Palo Alto, California
Cloud Engineering
DevOps
Solutions Engineering & Architecture
$233k - $325k/yr
10,000+

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JPMorganChase
Principal Software Engineer - Developer Platform Engineering
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JPMorganChase
New 7h ago
Principal Software Engineer - Developer Platform Engineering
JPMorganChase
Palo Alto, California
Health & Safety
Maintenance & Repair
Skilled Trades
$204k - $285k/yr
10,000+

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JPMorganChase
SR Principal Software Engineer - LLM Engineering
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JPMorganChase
New 13h ago
SR Principal Software Engineer - LLM Engineering
JPMorganChase
Palo Alto, California
Biotech & Life Sciences
Clinical Trials & Medical Research
Research & Academia
$233k - $325k/yr
Doctoral degree in Computer Science
10,000+

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Pika
Principal Engineer, Product
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Pika
Added 3d ago
Principal Engineer, Product
Pika
Palo Alto, California
Data Engineering
Data Science
ML (Machine Learning)
Software Engineering
11-50

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JPMorganChase
Principal Software Engineer - High Performance Computing
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JPMorganChase
Added 3d ago
Principal Software Engineer - High Performance Computing
JPMorganChase
Palo Alto, California
AI (Artificial Intelligence)
Data Science
ML (Machine Learning)
Software Engineering
$204k - $285k/yr
Doctoral degree in Computer Science
10,000+

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See All 815+ Principal Engineer Jobs in Palo Alto

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Principal Engineer Job Market in Palo Alto

Who's Hiring

  • JPMorganChase
    JPMorganChase408
  • Pika
    Pika102
  • GenBio AI
    GenBio AI102
  • Amazon
    Amazon102
  • H
    HTEC102

Top Industries Hiring

  • Biotechnology & Pharmaceuticals

Principal Engineer Jobs in Palo Alto: Frequently Asked Questions

How do I get a principal engineer job in Palo Alto?

The strongest path into a principal engineer role in Palo Alto is through the city's deep tech and enterprise software employers clustered in Stanford Research Park and along the El Camino Real corridor. Candidates who stand out combine a record of leading complex system design with experience in AI, semiconductors, or cloud infrastructure. Referrals through Stanford alumni networks and direct outreach to engineering leaders at local companies consistently outperform cold applications in this market.

Which companies hire principal engineers in Palo Alto?

Employers hiring principal engineers in Palo Alto right now include JPMorganChase, Pika, and GenBio AI, based on current listings on Migrate Mate as of September 2026. Palo Alto's employer mix skews toward research-intensive technology companies, semiconductor firms, and enterprise software organizations with significant R&D investment.

Are there remote principal engineer jobs in Palo Alto?

Yes, though availability depends heavily on the role type. Principal engineering positions tied to hardware, lab environments, or on-site infrastructure tend to require in-person presence, while those focused on software architecture and distributed systems often support flexible arrangements. About 33% of principal engineer openings tied to Palo Alto are remote or hybrid as of September 2026. Software-focused and platform roles at Palo Alto's enterprise tech employers are the most likely to offer remote or hybrid flexibility.

How can I get a principal engineer job in Palo Alto with little or no experience?

The most realistic entry path is through a senior software engineer or staff engineer role at one of Palo Alto's mid-size technology companies, where promotion cycles to principal can move faster than at larger firms. Employers in the Stanford Research Park and early-stage companies along University Avenue frequently hire senior engineers with five or more years of experience and a clear architecture portfolio, then develop them internally toward principal-level scope.

Which industries hire the most principal engineers in Palo Alto?

The sectors hiring the most principal engineers in Palo Alto are Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of September 2026. Palo Alto's concentration of semiconductor companies, AI research labs, and enterprise software firms with Stanford ties drives consistent demand for engineers at the principal level.

See All 815+ Principal Engineer Jobs in Palo Alto

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