Principal Scientist Jobs in Wilmington, DE
Principal Scientist jobs in Wilmington are concentrated in the Brandywine Hundred corridor, downtown Wilmington, and the Wilmington Riverfront, where pharmaceutical, chemical, and materials science employers anchor the local market. Active demand comes from LANXESS, JPMorganChase, and Incyte Corporation. Find a role that fits below and apply directly.
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Nemours is looking to hire an Assistant Research Scientist . The Assistant Research Scientist will conduct research in a variety of clinical and translational research areas and be responsible for the planning and execution of a wide range of research projects. Individual will supervise and train laboratory technicians and students; teach laboratory techniques to fellows; assist in protocol development, securing external funding, supervise study execution, completion, and manuscript preparation. Recommended to hold or working toward academic rank (i.e. Instructor) at one of Nemours’ partner academic institutions.
Primary Responsibilities:
Plan and execute a wide range of projects in translational and clinical research.
Independently perform experiments using a range of scientific techniques.
Write abstracts for presentation and articles for publication in peer-reviewed journals.
Submit external funding grant applications to support ongoing research projects/protocols
Collaborate with Nemours clinical divisions and partner institutions to develop novel research protocols that align with strategic objectives
Interact with and train laboratory technicians and students.
Supervise study execution and completion.
Oversee the maintenance, safety, and running of the laboratory.
Qualifications:
- Post Graduate (e.g., Ph.D., M.D., J.D.)
- Experience a minimum of 1-3 years relevant research experience required
Nemours is looking to hire an Assistant Research Scientist . The Assistant Research Scientist will conduct research in a variety of clinical and translational research areas and be responsible for the planning and execution of a wide range of research projects. Individual will supervise and train laboratory technicians and students; teach laboratory techniques to fellows; assist in protocol development, securing external funding, supervise study execution, completion, and manuscript preparation. Recommended to hold or working toward academic rank (i.e. Instructor) at one of Nemours’ partner academic institutions.
Primary Responsibilities:
Plan and execute a wide range of projects in translational and clinical research.
Independently perform experiments using a range of scientific techniques.
Write abstracts for presentation and articles for publication in peer-reviewed journals.
Submit external funding grant applications to support ongoing research projects/protocols
Collaborate with Nemours clinical divisions and partner institutions to develop novel research protocols that align with strategic objectives
Interact with and train laboratory technicians and students.
Supervise study execution and completion.
Oversee the maintenance, safety, and running of the laboratory.
Qualifications:
- Post Graduate (e.g., Ph.D., M.D., J.D.)
- Experience a minimum of 1-3 years relevant research experience required
See All 26 Principal Scientist Jobs in Wilmington
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Find Principal Scientist JobsPrincipal Scientist Job Market in Wilmington
Who's Hiring
- LANXESS6
- JPMorganChase4
- Incyte Corporation4
- Thermo Fisher Scientific4
- IFF3
Top Industries Hiring
- Chemicals & Materials10
- Fintech4
- Science & Research4
- Banking & Financial Services4
- Investment & Asset Management4
Principal Scientist Jobs in Wilmington: Frequently Asked Questions
How do I get a principal scientist job in Wilmington?
Target Wilmington's pharmaceutical and specialty chemicals sectors first, since those industries drive the heaviest principal scientist hiring in the city. Employers clustered along the Brandywine Hundred corridor and in downtown Wilmington favor candidates with deep domain expertise in drug development, polymer chemistry, or materials characterization. A publication record, patents, or demonstrated cross-functional project leadership helps differentiate applications in this concentrated, relationship-driven market.
Which companies hire principal scientists in Wilmington?
Wilmington principal scientist roles are posted by LANXESS, JPMorganChase, and Incyte Corporation and others right now, based on current listings on Migrate Mate as of July 2026. The local employer base skews toward large pharmaceutical manufacturers, specialty chemical producers, and contract research organizations that have long maintained operations in the greater Wilmington area.
Are there remote principal scientist jobs in Wilmington?
Yes, though with limits: principal scientist roles requiring laboratory work, pilot-plant oversight, or hands-on analytical testing are almost always on-site, while computational, regulatory affairs, and data-heavy positions lean more remote-friendly. About 0% of principal scientist openings tied to Wilmington are remote or hybrid as of July 2026, with flexibility most common in medical affairs and research informatics functions.
How can I get a principal scientist job in Wilmington with little or no experience?
The most realistic entry path in Wilmington is through a postdoctoral or associate scientist role at one of the area's pharmaceutical or specialty chemicals companies, which regularly use those positions as pipelines into principal scientist tracks. Contract research organizations in the Brandywine Hundred area also hire at the research scientist level and promote from within. Strong analytical skills, familiarity with GMP environments, and a graduate degree in chemistry, biochemistry, or a related field sharpen your candidacy locally.
Which industries hire the most principal scientists in Wilmington?
Most principal scientist openings in Wilmington sit in Chemicals & Materials, Fintech, and Science & Research, per current listings on Migrate Mate as of July 2026. Wilmington's historic role as a center for chemical innovation and its proximity to major East Coast biopharma clusters have made those sectors the dominant source of principal scientist demand in the city.
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