Project Director Jobs in San Francisco, CA
Project Director jobs in San Francisco are concentrated in SoMa, the Financial District, and Mission Bay, driven by demand across technology, healthcare, and construction. Employers hiring right now include GHD, Genentech, and Altos Labs. See the openings below and apply to the ones that match your experience.
Find Project Director JobsOverview
Showing 5 of 19+ Project Director jobs
Our Mission
Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.
Our Value
Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.
Diversity at Altos
Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.
What You Will Contribute To Altos
As a Project Team Leader & Executive Committee Business Manager, you will play a pivotal role that sits at the intersection of science, strategy, and operations. In this dual-capacity role, you will be accountable for the execution of our high-priority therapeutic programs while simultaneously serving as the strategic business manager for our Executive Committee. You will lead multidisciplinary teams through the complexities of the drug development lifecycle—from preclinical proof-of-concept through clinical trials and regulatory filing—while ensuring the highest level of operational efficiency, communication, and alignment within Altos’ Executive Committee. The ideal candidate possesses a rare blend of scientific expertise, project leadership skills, and executive-level business acumen required to align diverse stakeholders in a fast-paced biotech environment.
Key Responsibilities
Program Leadership & Strategy
- Cross-Functional Leadership: Lead a matrixed team of experts across Discovery, Preclinical, Clinical, and CMC (Manufacturing) to drive project advancement.
- Strategic Planning: Develop and present comprehensive options for the therapeutic program to senior management, including timing, target product profiles (TPPs), and cost.
- Stakeholder Management & Governance: Act as the primary point of communication for executive leadership. Lead governance and technical discussions within the team to interpret data and develop recommendations.
- Risk & Mitigation: Proactively identify risks and opportunities for acceleration in the development path. Build, present, and execute strategic contingency plans to bypass risks.
Executive Committee (EC) Business Management
- EC Agenda & Flow Management: Oversee EC agenda and minutes, ensuring high quality meetings and that discussions and decisions are accurately recorded and effectively communicated to align project execution with leadership priorities.
Who You Are
Minimum Qualifications
- Education: Ph.D., M.D., or Master’s degree in Life Sciences (Biology, Chemistry, etc.) or Business/MBA.
- Experience: 15+ years in the biotech or pharmaceutical industry, with at least 4 years in a dedicated project leadership or program management.
- Drug Development Track Record: Proven track record moving assets from research through IND-enabling and clinical studies.
- Committee Management: Demonstrated experience managing executive-level committees and interactions.
- Ability to manage cross-functional teams, delegate appropriately, and strong understanding of what goes into high quality decision making.
- Experience in areas from target validation and drug discovery through clinical trials.
Core Competencies
- Leadership & Influence: Ability to manage cross-functional teams, delegate appropriately, and possess a strong understanding of what goes into high-quality, high-stakes decision-making.
- Scientific & Industry Breadth: Deep experience spanning target validation and drug discovery through clinical trials.
- Modern Tech Savvy: Experience utilizing AI tools in drug discovery and development to optimize timelines and data interpretation.
- Executive Presence: Exceptional capability in building effective organizational relationships at senior, peer, and executive levels to get important work completed.
- Agility & Communication: A startup mindset—comfortable with ambiguity and able to alter direction when needed. Able to distill critical data to facilitate rapid executive decision-making.
- Communication Excellence: Exceptional written and verbal communication skills, with the ability to draft flawless executive minutes and present complex data while minimizing misunderstandings.
- Culture & Values: Through modeling and artful interactions, continue to build a culture of honesty, integrity, and respect for the organization.
Compensation
The salary range for Redwood City, CA:
- Project Team Leader: $313,200 - $401,500
Exact compensation may vary based on skills, experience, and location.
Equal Opportunity Employment
We value collaboration and scientific excellence. We believe that a culture of belonging are foundational to scientific innovation and inquiry. At Altos Labs, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining an inclusive environment. Altos Labs provides equal employment opportunities to all employees and applicants for employment, without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. Altos prohibits unlawful discrimination and harassment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training. Thank you for your interest in Altos Labs where we strive for a culture of scientific excellence, learning, and belonging.
Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at https://www.linkedin.com/pulse/how-spot-avoid-online-job-scams-biron-clark/
Our Mission
Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.
Our Value
Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.
Diversity at Altos
Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.
What You Will Contribute To Altos
As a Project Team Leader & Executive Committee Business Manager, you will play a pivotal role that sits at the intersection of science, strategy, and operations. In this dual-capacity role, you will be accountable for the execution of our high-priority therapeutic programs while simultaneously serving as the strategic business manager for our Executive Committee. You will lead multidisciplinary teams through the complexities of the drug development lifecycle—from preclinical proof-of-concept through clinical trials and regulatory filing—while ensuring the highest level of operational efficiency, communication, and alignment within Altos’ Executive Committee. The ideal candidate possesses a rare blend of scientific expertise, project leadership skills, and executive-level business acumen required to align diverse stakeholders in a fast-paced biotech environment.
Key Responsibilities
Program Leadership & Strategy
- Cross-Functional Leadership: Lead a matrixed team of experts across Discovery, Preclinical, Clinical, and CMC (Manufacturing) to drive project advancement.
- Strategic Planning: Develop and present comprehensive options for the therapeutic program to senior management, including timing, target product profiles (TPPs), and cost.
- Stakeholder Management & Governance: Act as the primary point of communication for executive leadership. Lead governance and technical discussions within the team to interpret data and develop recommendations.
- Risk & Mitigation: Proactively identify risks and opportunities for acceleration in the development path. Build, present, and execute strategic contingency plans to bypass risks.
Executive Committee (EC) Business Management
- EC Agenda & Flow Management: Oversee EC agenda and minutes, ensuring high quality meetings and that discussions and decisions are accurately recorded and effectively communicated to align project execution with leadership priorities.
Who You Are
Minimum Qualifications
- Education: Ph.D., M.D., or Master’s degree in Life Sciences (Biology, Chemistry, etc.) or Business/MBA.
- Experience: 15+ years in the biotech or pharmaceutical industry, with at least 4 years in a dedicated project leadership or program management.
- Drug Development Track Record: Proven track record moving assets from research through IND-enabling and clinical studies.
- Committee Management: Demonstrated experience managing executive-level committees and interactions.
- Ability to manage cross-functional teams, delegate appropriately, and strong understanding of what goes into high quality decision making.
- Experience in areas from target validation and drug discovery through clinical trials.
Core Competencies
- Leadership & Influence: Ability to manage cross-functional teams, delegate appropriately, and possess a strong understanding of what goes into high-quality, high-stakes decision-making.
- Scientific & Industry Breadth: Deep experience spanning target validation and drug discovery through clinical trials.
- Modern Tech Savvy: Experience utilizing AI tools in drug discovery and development to optimize timelines and data interpretation.
- Executive Presence: Exceptional capability in building effective organizational relationships at senior, peer, and executive levels to get important work completed.
- Agility & Communication: A startup mindset—comfortable with ambiguity and able to alter direction when needed. Able to distill critical data to facilitate rapid executive decision-making.
- Communication Excellence: Exceptional written and verbal communication skills, with the ability to draft flawless executive minutes and present complex data while minimizing misunderstandings.
- Culture & Values: Through modeling and artful interactions, continue to build a culture of honesty, integrity, and respect for the organization.
Compensation
The salary range for Redwood City, CA:
- Project Team Leader: $313,200 - $401,500
Exact compensation may vary based on skills, experience, and location.
Equal Opportunity Employment
We value collaboration and scientific excellence. We believe that a culture of belonging are foundational to scientific innovation and inquiry. At Altos Labs, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining an inclusive environment. Altos Labs provides equal employment opportunities to all employees and applicants for employment, without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. Altos prohibits unlawful discrimination and harassment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training. Thank you for your interest in Altos Labs where we strive for a culture of scientific excellence, learning, and belonging.
Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at https://www.linkedin.com/pulse/how-spot-avoid-online-job-scams-biron-clark/
See All 19 Project Director Jobs in San Francisco
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Find Project Director JobsProject Director Job Market in San Francisco
Who's Hiring
- GHD2
- Genentech2
- Altos Labs2
- Visa1
- Meter1
Top Industries Hiring
- Consulting & Professional Services4
- Medical Devices2
- Technology & Software2
- Construction & Real Estate2
- Biotechnology & Pharmaceuticals2
Project Director Jobs in San Francisco: Frequently Asked Questions
How do I get a project director job in San Francisco?
Focus your search on San Francisco's largest hiring sectors: enterprise technology in SoMa and Mid-Market, life sciences and hospital systems anchored in Mission Bay and the Inner Sunset, and real estate development along the waterfront and Transbay corridor. Candidates who combine PMP or similar credentials with direct experience managing cross-functional teams in one of these verticals move fastest. A portfolio showing complex, multi-stakeholder projects delivered in a fast-paced urban environment gives you a clear edge here.
Which companies hire project directors in San Francisco?
Companies currently hiring project directors in San Francisco include GHD, Genentech, and Altos Labs, per current listings on Migrate Mate as of June 2026. San Francisco's employer mix skews heavily toward large technology firms, academic medical centers, and general contractors managing major civic and commercial construction projects throughout the city.
Are there remote project director jobs in San Francisco?
Yes, though availability depends heavily on the role type. About 25% of project director openings tied to San Francisco are remote or hybrid as of June 2026, with remote arrangements far more common in software and digital product delivery than in construction, healthcare operations, or facilities management, which require consistent on-site presence. Technology and consulting firms in SoMa lead the remote-friendly share.
How can I get a project director job in San Francisco with little or no experience?
The most realistic entry path in San Francisco is through a project coordinator or program analyst role at one of the city's large technology companies, hospital networks like UCSF Health, or a general contractor active in the Transbay and Mission Bay development zones. These employers promote internally and value candidates who demonstrate ownership over timelines and stakeholder communication early. Volunteering with civic organizations or nonprofits running capital projects in San Francisco can also build a verifiable portfolio before you move into a director-level search.
Which industries hire the most project directors in San Francisco?
San Francisco project director roles concentrate in Consulting & Professional Services, Medical Devices, and Technology & Software, based on current listings on Migrate Mate as of June 2026. This reflects the city's position as a global technology hub anchored in SoMa and the Financial District, combined with sustained capital investment in Mission Bay's life sciences campus and ongoing large-scale commercial and infrastructure construction across the city.
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