Project Lead Jobs in Waltham, MA
Project Lead jobs in Waltham concentrate in life sciences, enterprise technology, and defense contracting, with demand anchored in the Waltham Woods, Bear Hill, and Route 128 corridor business districts. Employers actively hiring include TRC, Vantage Builders, and ENTRUST Solutions. Scan the live roles below and apply to whichever ones fit.
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Entity: CSL Behring
Job Category: Research Development & Sciences
Job Family: R&D Project Management
Job Type: Full Time
Location: Waltham, Massachusetts, United States
Employer Reference: R-282451
Job Description
Could you be our next Associate Director, Regulatory Project Manager? The job is in our Waltham MA, King of Prussia PA, Glattbrugg Switzerland or Maidenhead UK Office. This is a hybrid position and is onsite three days a week.
You will lead global regulatory project planning and execution across CSL’s product portfolio, ensuring timely delivery of submissions and improvement initiatives aligned with GRA strategy. This role oversees submission coordination, and cross-functional collaboration to meet global health authority requirements and drive operational excellence.
Main Responsibilities & Accountabilities:
Regulatory Project Leadership
Lead end-to-end project management of regulatory initiatives and improvement projects (initiation through closure) within budget, scope, and timelines.
Develop, execute, and monitor project plans, risk logs, communication strategies, and status reporting.
Submission Coordination
Oversee regulatory submissions per CSL’s Global Submission Management Process.
Lead submission team meetings, content planning, tracking in RIMS, and ensure on-time, compliant submissions.
Liaise with global, regional, and local teams for successful execution
Continuous Improvement & Governance
Manage improvement projects portfolio in alignment with GRA strategy and executive priorities.
Support quarterly reporting to Portfolio Committee and implement process efficiencies.
Contribute to governance, best practices, and standardization across regulatory operations.
Management & Collaboration
May be required to manage Regulatory Project Managers
Leads cross-functionally with Regulatory, Clinical, Manufacturing, POE (GPM) and external partners.
Mentor junior project managers and support training on submission processes and tools.
Liaise with Regulatory Policy to ensure awareness and incorporation of policy changes into Regulatory strategy, planning, and execution
Qualifications & Experience
Bachelor’s degree in Life Sciences or Business required; advanced degree (MSc, PhD, MBA) and PMP certification preferred.
7+ years of experience in pharma/biotech industry with a focus on biologics and regulatory affairs.
7+ years’ experience managing global, cross-functional projects in a matrix environment.
Strong knowledge of global regulatory submission processes, drug development lifecycle, and project governance.
Demonstrated success in delivering complex projects on time and within scope.
The expected base salary range for this position at hiring is $170,000-210,000. Please note this salary range reflects the minimum and maximum base pay that CSL expects to pay for this position at the time of this posting in MA. Individual base salary for a successful candidate is determined by qualifications, skill level, experience, competencies and other relevant factors. In addition to base salary, total compensation for this role may also include incentive compensation and equity.
#LI-HYBRID
About CSL Behring
CSL Behring is a global biotherapeutics leader driven by our promise to save lives. Focused on serving patients' needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives.
CSL Behring operates one of the world's largest plasma collection networks, CSL Plasma. Our parent company, CSL, headquartered in Melbourne, Australia, employs 32,000 people, and delivers its lifesaving therapies to people in more than 100 countries.
To learn more about CSL, CSL Behring, CSL Seqirus and CSL Vifor visit https://www.csl.com/ and CSL Plasma at https://www.cslplasma.com/.
Our Benefits
For more information on CSL benefits visit How CSL Supports Your Well-being | CSL.
You Belong at CSL
At CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future.
To learn more about inclusion and belonging visit https://www.csl.com/careers/inclusion-and-belonging
Equal Opportunity Employer
CSL is an Equal Opportunity Employer. If you are an individual with a disability and need a reasonable accommodation for any part of the application process, please visit https://www.csl.com/accessibility-statement.
Entity: CSL Behring
Job Category: Research Development & Sciences
Job Family: R&D Project Management
Job Type: Full Time
Location: Waltham, Massachusetts, United States
Employer Reference: R-282451
Job Description
Could you be our next Associate Director, Regulatory Project Manager? The job is in our Waltham MA, King of Prussia PA, Glattbrugg Switzerland or Maidenhead UK Office. This is a hybrid position and is onsite three days a week.
You will lead global regulatory project planning and execution across CSL’s product portfolio, ensuring timely delivery of submissions and improvement initiatives aligned with GRA strategy. This role oversees submission coordination, and cross-functional collaboration to meet global health authority requirements and drive operational excellence.
Main Responsibilities & Accountabilities:
Regulatory Project Leadership
Lead end-to-end project management of regulatory initiatives and improvement projects (initiation through closure) within budget, scope, and timelines.
Develop, execute, and monitor project plans, risk logs, communication strategies, and status reporting.
Submission Coordination
Oversee regulatory submissions per CSL’s Global Submission Management Process.
Lead submission team meetings, content planning, tracking in RIMS, and ensure on-time, compliant submissions.
Liaise with global, regional, and local teams for successful execution
Continuous Improvement & Governance
Manage improvement projects portfolio in alignment with GRA strategy and executive priorities.
Support quarterly reporting to Portfolio Committee and implement process efficiencies.
Contribute to governance, best practices, and standardization across regulatory operations.
Management & Collaboration
May be required to manage Regulatory Project Managers
Leads cross-functionally with Regulatory, Clinical, Manufacturing, POE (GPM) and external partners.
Mentor junior project managers and support training on submission processes and tools.
Liaise with Regulatory Policy to ensure awareness and incorporation of policy changes into Regulatory strategy, planning, and execution
Qualifications & Experience
Bachelor’s degree in Life Sciences or Business required; advanced degree (MSc, PhD, MBA) and PMP certification preferred.
7+ years of experience in pharma/biotech industry with a focus on biologics and regulatory affairs.
7+ years’ experience managing global, cross-functional projects in a matrix environment.
Strong knowledge of global regulatory submission processes, drug development lifecycle, and project governance.
Demonstrated success in delivering complex projects on time and within scope.
The expected base salary range for this position at hiring is $170,000-210,000. Please note this salary range reflects the minimum and maximum base pay that CSL expects to pay for this position at the time of this posting in MA. Individual base salary for a successful candidate is determined by qualifications, skill level, experience, competencies and other relevant factors. In addition to base salary, total compensation for this role may also include incentive compensation and equity.
#LI-HYBRID
About CSL Behring
CSL Behring is a global biotherapeutics leader driven by our promise to save lives. Focused on serving patients' needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives.
CSL Behring operates one of the world's largest plasma collection networks, CSL Plasma. Our parent company, CSL, headquartered in Melbourne, Australia, employs 32,000 people, and delivers its lifesaving therapies to people in more than 100 countries.
To learn more about CSL, CSL Behring, CSL Seqirus and CSL Vifor visit https://www.csl.com/ and CSL Plasma at https://www.cslplasma.com/.
Our Benefits
For more information on CSL benefits visit How CSL Supports Your Well-being | CSL.
You Belong at CSL
At CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future.
To learn more about inclusion and belonging visit https://www.csl.com/careers/inclusion-and-belonging
Equal Opportunity Employer
CSL is an Equal Opportunity Employer. If you are an individual with a disability and need a reasonable accommodation for any part of the application process, please visit https://www.csl.com/accessibility-statement.
See All 20 Project Lead Jobs in Waltham
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Find Project Lead JobsProject Lead Job Market in Waltham
Who's Hiring
Top Industries Hiring
- Consulting & Professional Services
- Technology & Software
- Education
- Cybersecurity
- Construction & Real Estate
Project Lead Jobs in Waltham: Frequently Asked Questions
How do I get a project lead job in Waltham?
Focus on the sectors driving most of Waltham's project lead hiring: biotech and medical device companies along Route 128, enterprise software and IT services firms in Waltham Woods, and defense contractors near Bear Hill. Candidates who combine PMP certification or equivalent credentials with hands-on experience managing cross-functional teams stand out. Familiarity with regulated industries like life sciences or government contracting gives a real edge in this market.
Which companies hire project leads in Waltham?
Companies currently hiring project leads in Waltham include TRC, Vantage Builders, and ENTRUST Solutions, per current listings on Migrate Mate as of July 2026. Waltham's employer mix leans toward mid-size and large companies in life sciences, defense, and enterprise technology, many of which maintain dedicated project management offices.
Are there remote project lead jobs in Waltham?
Yes, though availability depends heavily on the role type. About 38% of project lead openings tied to Waltham are remote or hybrid as of July 2026, with remote work more common for software and IT-focused project leads than for those managing lab, manufacturing, or defense facility operations in Waltham.
How can I get a project lead job in Waltham with little or no experience?
The most realistic entry path in Waltham is moving into a junior project coordinator or associate program manager role at one of the many mid-size biotech or software companies headquartered here, where smaller teams often give early-career candidates real ownership faster. Building experience with Agile or Scrum frameworks, earning a CAPM certification, and targeting companies that run formal associate PM programs gives candidates a concrete advantage locally.
Which industries hire the most project leads in Waltham?
Waltham project lead roles concentrate in Consulting & Professional Services, Technology & Software, and Education, based on current listings on Migrate Mate as of July 2026. Waltham's dense cluster of Route 128 biotech campuses, defense contractors, and enterprise software firms creates consistent demand for project leads who can manage complex, compliance-driven work across multiple stakeholders.
Related Jobs in Massachusetts
See All 20 Project Lead Jobs in Waltham
Find roles in Waltham that match your experience and apply in just a few clicks.
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