Project Lead Jobs in St. Louis, MO

Project Lead jobs in St. Louis are in strong demand, concentrated in Clayton, Cortex Innovation Community, and the downtown Central Business District across healthcare IT, logistics, defense contracting, and financial services. Employers hiring right now include ECS Limited, BJC HealthCare, and SERVPRO. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles69
Top employerECS Limited
Work type50% On-site
Top credentialBachelor's degree in engineering
Companies hiring14

Showing 5 of 69+ Project Lead jobs

BJC HealthCare
Sr. Project Manager
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BJC HealthCare
New 14h ago
Sr. Project Manager
BJC HealthCare
St. Louis, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
$76k.8 - $124k.2/yr
Hybrid
Six Sigma Certification
10,000+

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Mullins Mechanical
Assistant Project Manager - (Onsite - HVAC, Plumbing, Mechanical) - Abernathy, Texas
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Mullins Mechanical
New 17h ago
Assistant Project Manager - (Onsite - HVAC, Plumbing, Mechanical) - Abernathy, Texas
Mullins Mechanical
St. Louis, Missouri
Customer Service
Customer Success
Customer Support
On-Site
Bachelor of Science

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Nestlé Purina
Senior Project Engineering Manager (End to End Project Manager)
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Nestlé Purina
Added 1d ago
Senior Project Engineering Manager (End to End Project Manager)
Nestlé Purina
St. Louis, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
$151k.8 - $194k/yr
Bachelor's degree in engineering
10,000+

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Perficient
Senior Project Manager / Scrum Master (QA & Testing Delivery) - STL, MO
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Perficient
Added 1d ago
Senior Project Manager / Scrum Master (QA & Testing Delivery) - STL, MO
Perficient
St. Louis, Missouri
Compliance & Legal
IT Support
Project Management
Technical Program Management
5,001-10,000

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Washington University in St. Louis
Clinical Research Project Manager II - Cardiology
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Washington University in St. Louis
Added 1d ago
Clinical Research Project Manager II - Cardiology
Washington University in St. Louis
St. Louis, Missouri
Business Strategy
Compliance & Risk
Consulting & Professional Services
$75k - $129k/yr
Hybrid
Bachelor's degree
10,000+

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See All 69 Project Lead Jobs in St. Louis

Find roles in St. Louis that match your experience and apply in just a few clicks.

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Project Lead Job Market in St. Louis

Who's Hiring

ECS Limited
ECS Limited9 open roles
BJC HealthCare
BJC HealthCare9 open roles
SERVPRO
SERVPRO4 open roles

Top Industries Hiring

  • Education
  • Construction & Real Estate
  • Waste Management & Environmental Services

Project Lead Jobs in St. Louis: Frequently Asked Questions

How do I get a project lead job in St. Louis?

Focus your search on St. Louis's dominant hiring sectors: healthcare systems, defense and aerospace contractors, logistics and supply chain firms, and financial technology companies. The Cortex Innovation Community and Clayton's corporate corridor concentrate a large share of openings. Candidates who demonstrate cross-functional coordination experience, familiarity with Agile or PMP frameworks, and the ability to manage stakeholders in regulated industries move fastest in this market.

Which companies hire project leads in St. Louis?

St. Louis project lead roles are posted by ECS Limited, BJC HealthCare, and SERVPRO and others right now, based on current listings on Migrate Mate as of September 2026. St. Louis draws hiring from large integrated health systems, legacy aerospace and defense firms, regional banks, and a growing cluster of logistics technology companies headquartered in or near the metro.

Are there remote project lead jobs in St. Louis?

Yes, though availability depends heavily on the role type. Project leads in software, IT, and analytics tend to work remotely or hybrid, while those in construction, manufacturing, and lab environments are almost always on-site. About 50% of project lead openings tied to St. Louis are remote or hybrid as of September 2026. The strongest remote options in this market come from healthcare IT and fintech employers based in the region.

How can I get a project lead job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is moving into a project coordinator or junior project manager role at one of the city's large health systems or defense contractors, where structured training programs are common. Washington University, BJC HealthCare, and Boeing-affiliated suppliers regularly bring in early-career candidates for coordinator-level roles that ladder into project lead positions. Building proficiency in tools like Jira, Smartsheet, or MS Project and earning a CAPM or equivalent certificate gives local candidates a measurable edge over competitors.

Which industries hire the most project leads in St. Louis?

The sectors hiring the most project leads in St. Louis are Education, Construction & Real Estate, and Waste Management & Environmental Services, based on current listings on Migrate Mate as of September 2026. St. Louis's concentration of major health systems, a longstanding aerospace and defense presence, and a growing logistics technology corridor make those industries the primary drivers of local project lead demand.

See All 69 Project Lead Jobs in St. Louis

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