Project Lead Jobs in Durham, NC

Project Lead jobs in Durham are in strong demand, concentrated in Research Triangle Park, Downtown Durham, and the Erwin Road corridor, across life sciences, technology, and healthcare. Employers hiring right now include DPR Construction, IQVIA, and Gilero. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles138+
Top employerDPR Construction
Work type66% On-site
Top credentialBachelor's
Companies hiring8

Showing 5 of 138+ Project Lead jobs

DPR Construction
Project Manager
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DPR Construction
New 5h ago
Project Manager
DPR Construction
Durham, North Carolina
Project & Program Management
Construction Management
Project Management
On-Site
Bachelor's
10,000+

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DPR Construction
Sr Project Manager
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DPR Construction
Added 1d ago
Sr Project Manager
DPR Construction
Durham, North Carolina
Project & Program Management
Construction Management
Project Management
On-Site
Bachelor's
10,000+

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DPR Construction
Project Manager - Concrete
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DPR Construction
Added 1d ago
Project Manager - Concrete
DPR Construction
Durham, North Carolina
Account Management
Customer Success
Sales
Bachelor's degree in construction management
10,000+

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DPR Construction
Project Manager - Drywall
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DPR Construction
Added 1d ago
Project Manager - Drywall
DPR Construction
Durham, North Carolina
Account Management
Customer Success
Sales
Bachelor's degree in construction management
10,000+

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IQVIA
FSP Clinical Project Manager
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IQVIA
Added 1d ago
FSP Clinical Project Manager
IQVIA
Durham, North Carolina
Biotech & Life Sciences
Clinical Trials & Medical Research
Research & Academia
$93k - $233k/yr
Remote (US)
Bachelor's degree
10,000+

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See All 138+ Project Lead Jobs in Durham

Find roles in Durham that match your experience and apply in just a few clicks.

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Project Lead Job Market in Durham

Who's Hiring

  • DPR Construction
    DPR Construction50
  • IQVIA
    IQVIA13
  • Gilero
    Gilero13
  • A
    AICPA-CIMA13
  • K
    KONTEK Systems13

Top Industries Hiring

  • Construction & Real Estate

Project Lead Jobs in Durham: Frequently Asked Questions

How do I get a project lead job in Durham?

Focus your search on Durham's three dominant hiring sectors: life sciences and biotech clustered near Research Triangle Park, health systems anchored by Duke University Health System and UNC Health, and enterprise technology firms in the Downtown and Erwin Road corridors. Candidates who stand out locally tend to hold a PMP or similar credential, show experience coordinating cross-functional teams in regulated environments, and can demonstrate familiarity with the fast-moving research and clinical trial timelines common to Durham employers.

Which companies hire project leads in Durham?

Companies currently hiring project leads in Durham include DPR Construction, IQVIA, and Gilero, per current listings on Migrate Mate as of September 2026. Durham's employer mix skews heavily toward research institutions, hospital networks, and mid-to-large technology firms, so most openings come from organizations running complex, multi-phase projects rather than small startups.

Are there remote project lead jobs in Durham?

Yes, though availability depends heavily on the role type. Project lead positions tied to clinical operations, laboratory work, or on-site construction management are almost always in-person, while those in software delivery, enterprise IT, and program coordination tend to offer flexibility. About 34% of project lead openings tied to Durham are remote or hybrid as of September 2026, with the highest share coming from technology and professional services employers in the Research Triangle area.

How can I get a project lead job in Durham with little or no experience?

The most realistic entry path in Durham is moving into a project lead role from a coordinator or analyst position within a larger organization. Duke University, Duke Health, and major biotech employers in Research Triangle Park regularly hire project coordinators who can grow into lead roles over one to two years. Earning a CAPM certification, volunteering to run internal initiatives, and showing familiarity with Agile or clinical trial workflows gives early-career candidates a visible edge with Durham's research-heavy employer base.

Which industries hire the most project leads in Durham?

Durham project lead roles concentrate in Construction & Real Estate, based on current listings on Migrate Mate as of September 2026. Durham's position as the anchor city of Research Triangle Park draws a disproportionate share of biotech, pharmaceutical, and academic medical employers, all of which rely heavily on project leads to manage complex, compliance-driven workflows.

See All 138+ Project Lead Jobs in Durham

Find roles in Durham that match your experience and apply in just a few clicks.

Find Project Lead Jobs