Remote Principal Scientist Jobs
Remote Principal Scientist jobs are open across biotech, pharmaceuticals, data science, and clinical research at remote-first firms and distributed enterprise teams that have built fully asynchronous scientific workflows. Roles range from individual contributor research positions through staff and distinguished scientist levels requiring cross-functional leadership. Employers hiring remotely right now include CVS Health, Aimpoint Digital, and General Dynamics Information Technology. Scan the live roles below and apply to whichever ones fit.
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Showing 5 of 40+ Remote Principal Scientist jobs
***An active or rein-statable TS/SCI with Polygraph security clearance is REQUIRED. Please do not apply if you currently do not possess this level of clearance.***
Are you a Principal Data Scientist who is ready for a new challenge that will launch your career to the next level?
- Tired of being treated like a company drone?
- Tired of promised adventures during the hiring phase, then dropped off on a remote contract and never seen or heard from the mothership again?
- Our engineers were certainly tired of the same.
At GliaCell our slogan is “We make It happen”.
- We will immerse you in the latest technologies.
- We will develop and support your own personalized training program to continue your individual growth.
- We will provide you with work that matters with our mission-focused customers, and surround you with a family of brilliant engineers.
Culture isn’t something you need to talk about…if it just exists.
If this sounds interesting to you, then we’d like to have a discussion regarding your next adventure! If you want to be a drone, this isn’t the place for you.
We Make It Happen!
GliaCell Technologies focuses on Software & System Engineering in Enterprise and Cyber Security solution spaces. We excel at delivering stable and reliable software solutions using Agile Software Development principles. These provide us the capability to deliver a quick turn-around using interactive applications and the integration of industry standard software stacks.
GliaCell’s Enterprise capabilities include Full-Stack Application Development, Big Data, Cloud Technologies, Analytics, Machine Learning, AI, and DevOps Containerization. We also provide customer solutions in the areas of CND, CNE, and CNO by providing our customers with assessments and solutions in Threat Mitigation, Vulnerability Exposure, Penetration Testing, Threat Hunting, and Preventing Advanced Persistent Threat.
We Offer:
- Long term job security
- Competitive salaries & bonus opportunities
- Challenging work you are passionate about
- Ability to work with some amazingly talented people
Job Description:
GliaCell is seeking a Principal Data Scientist on one of our subcontracts. This is a full-time position offering the opportunity to support a U.S. Government customer. The mission is to provide technical expertise that assists in sustaining critical mission-related software and systems to a large government contract.
Key Requirements:
To be considered for this position you must have the following:
- Possess an active or rein-statable TS/SCI with Polygraph security clearance. (This position requires in-scope poly, within 7 years).
- U.S. Citizenship.
- Bachelor's degree or higher from an accredited college or university in a quantitative discipline (e.g., statistics, mathematics, operations research, engineering or computer science). A minimum of ten (10) years of experience in two (2) or more of the following: designing/implementing machine learning, data mining, advanced analytical algorithms, advanced statistical analysis, artificial intelligence, or software engineering with data analysis software such as R, Python, SAS, or MATLAB. An additional four (4) years of experience in software development, cloud development, analyzing datasets, or developing descriptive, predictive, and prescriptive analytics can be substituted for a Bachelor's degree.
- A Master’s Degree from an accredited college or university in a quantitative discipline can be substituted for two (2) years of experience for a total of eight (8) years of experience required. A Doctoral Degree from an accredited college or university in a quantitative discipline can be substituted for four (4) years of experience for a total of six (6) years of experience required.
- Work well independently as well as on a team.
- Strong communication skills.
Key Skills:
- Programming Languages: Proficiency in programming languages such as Python and R is crucial for data manipulation, analysis, and implementing algorithms. Python is favored for its simplicity and extensive libraries (like NumPy and pandas), while R is preferred for statistical analysis and data visualization.
- Statistical Analysis: A strong foundation in statistics and probability is necessary for analyzing data accurately and making informed decisions. Understanding concepts like regression analysis, hypothesis testing, and statistical distributions is essential.
- Machine Learning: Knowledge of machine learning algorithms and frameworks (such as TensorFlow and Scikit-Learn) is vital for building predictive models and automating decision-making processes.
- Data Wrangling: The ability to clean and organize complex datasets is critical. Data wrangling involves transforming raw data into a usable format, which is often time-consuming but necessary for effective analysis.
- Database Management: Familiarity with SQL and database management systems (like PostgreSQL and MongoDB) is essential for extracting and manipulating data stored in relational databases.
- Data Visualization: Skills in data visualization tools (such as Tableau and Matplotlib) help communicate findings effectively. Creating charts, graphs, and dashboards is crucial for making data understandable to stakeholders.
Location: Annapolis Junction, Maryland (Partial Telework of 16 hours per week is expected)
Note: Telework granted for this position does not become available until after the individual has been in the position for a period of time, has acclimated to tasking/duties, and has meaningful work that can be done remotely. Telework can also be removed at any time.
Salary Range: The salary range for this full-time position is $200,000 to $280,000. Our salary ranges are determined by position, level, skills, professional experience, relevant education and certifications. The range displayed on each job posting reflects the minimum and maximum target salaries for this position across our projects. Within the range, your salary is determined by your individual benefits package selection. Your recruiter can share more about the specific salary range for your preferred position during the hiring process.
Benefits:
- Medical, Dental, and Vision Coverage for Employee and Dependents
- Up to 25 Days of Paid Time Off
- Up to 40 hours of PTO Carryover
- 11 Federal Government Holidays
- Work From Home Opportunities
- 401K Company Contribution, Fully Vested Day 1
- Discretionary, Certification, and Sign-On Bonus Potential
- Employee Referral Bonus Program
- Annual Professional Development
- 100% Premium Covered for Life & Disability Insurances
- Additional Voluntary Life Insurance Coverage Available
- Employee Assistance Program
- Travel Protection Program
- Financial Planning Assistance
- Bereavement and Jury Duty Leave
- Monthly Team and Family Events
- Technology Budget
- Global Entry
- Annual Swag Budget
Learn more about GliaCell Technologies: https://gliacelltechnologies.applytojob.com/apply/
To apply for this position, respond to this job posting and attach an updated resume for us to review.
GliaCell Technologies, LLC is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, or disability status.
88eg23kw7X
***An active or rein-statable TS/SCI with Polygraph security clearance is REQUIRED. Please do not apply if you currently do not possess this level of clearance.***
Are you a Principal Data Scientist who is ready for a new challenge that will launch your career to the next level?
- Tired of being treated like a company drone?
- Tired of promised adventures during the hiring phase, then dropped off on a remote contract and never seen or heard from the mothership again?
- Our engineers were certainly tired of the same.
At GliaCell our slogan is “We make It happen”.
- We will immerse you in the latest technologies.
- We will develop and support your own personalized training program to continue your individual growth.
- We will provide you with work that matters with our mission-focused customers, and surround you with a family of brilliant engineers.
Culture isn’t something you need to talk about…if it just exists.
If this sounds interesting to you, then we’d like to have a discussion regarding your next adventure! If you want to be a drone, this isn’t the place for you.
We Make It Happen!
GliaCell Technologies focuses on Software & System Engineering in Enterprise and Cyber Security solution spaces. We excel at delivering stable and reliable software solutions using Agile Software Development principles. These provide us the capability to deliver a quick turn-around using interactive applications and the integration of industry standard software stacks.
GliaCell’s Enterprise capabilities include Full-Stack Application Development, Big Data, Cloud Technologies, Analytics, Machine Learning, AI, and DevOps Containerization. We also provide customer solutions in the areas of CND, CNE, and CNO by providing our customers with assessments and solutions in Threat Mitigation, Vulnerability Exposure, Penetration Testing, Threat Hunting, and Preventing Advanced Persistent Threat.
We Offer:
- Long term job security
- Competitive salaries & bonus opportunities
- Challenging work you are passionate about
- Ability to work with some amazingly talented people
Job Description:
GliaCell is seeking a Principal Data Scientist on one of our subcontracts. This is a full-time position offering the opportunity to support a U.S. Government customer. The mission is to provide technical expertise that assists in sustaining critical mission-related software and systems to a large government contract.
Key Requirements:
To be considered for this position you must have the following:
- Possess an active or rein-statable TS/SCI with Polygraph security clearance. (This position requires in-scope poly, within 7 years).
- U.S. Citizenship.
- Bachelor's degree or higher from an accredited college or university in a quantitative discipline (e.g., statistics, mathematics, operations research, engineering or computer science). A minimum of ten (10) years of experience in two (2) or more of the following: designing/implementing machine learning, data mining, advanced analytical algorithms, advanced statistical analysis, artificial intelligence, or software engineering with data analysis software such as R, Python, SAS, or MATLAB. An additional four (4) years of experience in software development, cloud development, analyzing datasets, or developing descriptive, predictive, and prescriptive analytics can be substituted for a Bachelor's degree.
- A Master’s Degree from an accredited college or university in a quantitative discipline can be substituted for two (2) years of experience for a total of eight (8) years of experience required. A Doctoral Degree from an accredited college or university in a quantitative discipline can be substituted for four (4) years of experience for a total of six (6) years of experience required.
- Work well independently as well as on a team.
- Strong communication skills.
Key Skills:
- Programming Languages: Proficiency in programming languages such as Python and R is crucial for data manipulation, analysis, and implementing algorithms. Python is favored for its simplicity and extensive libraries (like NumPy and pandas), while R is preferred for statistical analysis and data visualization.
- Statistical Analysis: A strong foundation in statistics and probability is necessary for analyzing data accurately and making informed decisions. Understanding concepts like regression analysis, hypothesis testing, and statistical distributions is essential.
- Machine Learning: Knowledge of machine learning algorithms and frameworks (such as TensorFlow and Scikit-Learn) is vital for building predictive models and automating decision-making processes.
- Data Wrangling: The ability to clean and organize complex datasets is critical. Data wrangling involves transforming raw data into a usable format, which is often time-consuming but necessary for effective analysis.
- Database Management: Familiarity with SQL and database management systems (like PostgreSQL and MongoDB) is essential for extracting and manipulating data stored in relational databases.
- Data Visualization: Skills in data visualization tools (such as Tableau and Matplotlib) help communicate findings effectively. Creating charts, graphs, and dashboards is crucial for making data understandable to stakeholders.
Location: Annapolis Junction, Maryland (Partial Telework of 16 hours per week is expected)
Note: Telework granted for this position does not become available until after the individual has been in the position for a period of time, has acclimated to tasking/duties, and has meaningful work that can be done remotely. Telework can also be removed at any time.
Salary Range: The salary range for this full-time position is $200,000 to $280,000. Our salary ranges are determined by position, level, skills, professional experience, relevant education and certifications. The range displayed on each job posting reflects the minimum and maximum target salaries for this position across our projects. Within the range, your salary is determined by your individual benefits package selection. Your recruiter can share more about the specific salary range for your preferred position during the hiring process.
Benefits:
- Medical, Dental, and Vision Coverage for Employee and Dependents
- Up to 25 Days of Paid Time Off
- Up to 40 hours of PTO Carryover
- 11 Federal Government Holidays
- Work From Home Opportunities
- 401K Company Contribution, Fully Vested Day 1
- Discretionary, Certification, and Sign-On Bonus Potential
- Employee Referral Bonus Program
- Annual Professional Development
- 100% Premium Covered for Life & Disability Insurances
- Additional Voluntary Life Insurance Coverage Available
- Employee Assistance Program
- Travel Protection Program
- Financial Planning Assistance
- Bereavement and Jury Duty Leave
- Monthly Team and Family Events
- Technology Budget
- Global Entry
- Annual Swag Budget
Learn more about GliaCell Technologies: https://gliacelltechnologies.applytojob.com/apply/
To apply for this position, respond to this job posting and attach an updated resume for us to review.
GliaCell Technologies, LLC is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, or disability status.
88eg23kw7X
See All 40 Remote Principal Scientist Jobs
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Find JobsRemote Principal Scientist Job Market
Who's Hiring
Top Industries Hiring
- Consulting & Professional Services
- Retail
What Employers Look For
The qualifications that appear most often in remote principal scientist jobs.
- PhD in a relevant scientific discipline such as biology, chemistry, biochemistry, or a related field
- Eight or more years of hands-on research experience in industry or government settings
- Demonstrated record of first- or senior-author peer-reviewed publications and patent contributions
- Proficiency with domain-specific tools such as molecular modeling software, analytical instrumentation, or statistical programming languages
- Experience leading cross-functional project teams and mentoring junior scientists or postdoctoral researchers
- Familiarity with regulatory submission processes such as IND, NDA, or equivalent documentation standards
Tips for Your Remote Principal Scientist Job Search
Apply early to remote roles that fit
Migrate Mate lists remote principal scientist openings from across the U.S. in one place, so you can find roles that match your domain and apply directly. Remote positions at well-known firms fill fast, so apply as soon as a role appears rather than waiting.
Document your async scientific communication style
Remote employers screen specifically for written communication. Update your materials to show examples of scientific memos, cross-functional research updates, or async decision documents you've authored, because these signal you can lead science without in-person context.
Highlight end-to-end program ownership
Remote principal scientist roles require you to move a research program forward independently. Describe specific programs you owned from hypothesis through data readout or publication, naming the decisions you made without escalating, to show you can operate without daily oversight.
Signal fluency with distributed research tools
List the collaboration and lab informatics tools you use, such as Benchling, Confluence, Notion, or electronic lab notebooks, alongside standard scientific software. Remote hiring managers look for candidates already comfortable in the async stack their distributed team runs on.
Remote Principal Scientist Jobs: Frequently Asked Questions
How do I get a remote principal scientist job?
Remote principal scientist roles go to candidates who demonstrate independent scientific leadership without needing on-site oversight. Employers screen hard for written communication, because async updates and documentation replace hallway conversations. Strong candidates show a publication or patent record, experience driving a research program end-to-end, and fluency with collaborative tools like Notion, Confluence, or Benchling. Remote-first biotech and pharma companies are the most consistent hirers for fully distributed principal scientist positions.
Which companies hire remote principal scientists?
Employers currently hiring remote principal scientists include CVS Health, Aimpoint Digital, and General Dynamics Information Technology, per current remote listings on Migrate Mate as of September 2026. Remote-first biotech firms, distributed pharma R&D teams, and tech companies with computational biology or data science functions are the most consistent sources of fully remote principal scientist openings.
Can you get a remote principal scientist job with no experience?
Yes, but remote entry paths at the principal scientist level are narrow, because remote employers expect you to drive research programs with minimal hand-holding from day one. Early-career candidates who land remote roles typically come from strong PhD or postdoctoral work, have first-author publications, or have led a discrete project they can describe in detail. Smaller remote-first startups and contract research roles are the most realistic entry points when direct industry experience is limited.
Do you need a degree for remote principal scientist jobs?
Usually, yes. The principal scientist title almost universally requires at minimum a master's degree, and the large majority of postings expect a PhD in a relevant scientific discipline. Remote employers weigh published research output, demonstrated program ownership, and domain depth alongside formal credentials. Candidates without advanced degrees who have built equivalent expertise through industry R&D roles can still compete, but a graduate degree remains the standard expectation.
Which industries hire the most remote principal scientists?
Remote principal scientist roles concentrate in Consulting & Professional Services and Retail, based on current remote listings on Migrate Mate as of September 2026. These sectors have adopted distributed research models because computational work, regulatory writing, and data-heavy scientific programs can run effectively across time zones without a shared lab bench.
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Find roles that match your experience and apply in just a few clicks.
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