Safety Director Jobs
Safety Director jobs are open across construction, manufacturing, healthcare, and logistics, at every level from site safety manager to VP of EHS, with specializations in OSHA compliance, industrial hygiene, and environmental health and safety. See the openings below and apply to the ones that match your experience.
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Showing 5 of 295+ Safety Director jobs
Who We Are:
Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. (*in collaboration with AbbVie)
About the Role:
In this highly visible role, you will serve as a strategic medical safety leader, providing expert medical oversight of our evolving pipeline and safety profiles driving proactive benefit-risk management throughout the product lifecycle.You will partner closely with senior leaders across Drug Safety, Clinical Development, Regulatory Affairs, Medical Affairs, and other cross-functional teams to translate complex safety data into actionable insights, inform critical decisions, and ensure a comprehensive, science-driven approach to patient safety.
This opportunity is well suited for a physician with strong pharmacovigilance expertise who enjoys balancing hands-on medical and scientific evaluation with strategic leadership, cross-functional influence, and meaningful product ownership.
_
Your Contributions (include, but are not limited to):
Product Safety Strategy & Medical Leadership
- Serve as the medical safety expert for assigned marketed and/or investigational therapies, with accountability for the ongoing evaluation and management of their safety profiles
- Lead the development and execution of global safety surveillance and risk management strategies, ensuring proactive identification, assessment, and mitigation of emerging safety concerns
- Provide strategic medical guidance to senior leadership and cross-functional governance teams on safety-related decisions, evolving benefit-risk considerations, and product lifecycle management
- Drive safety strategy and decision-making through the interpretation of complex clinical and post-marketing safety data
Pharmacovigilance & Signal Management
- Provide medical guidance for signal detection, evaluation, assessment, and management activities, including the investigation of emerging safety trends and potential risks
- Lead aggregate safety data reviews and provide medical interpretation to support ongoing safety surveillance and benefit-risk evaluations
- Oversee and contribute to the medical review of individual case safety reports, including seriousness, expectedness, causality assessments, and clinical interpretation, as needed
- Partner with pharmacovigilance and safety operations teams to ensure robust, compliant, and scientifically sound safety surveillance practices
Regulatory Strategy & Safety Governance
- Provide medical oversight and strategic input into safety-related regulatory submissions and periodic safety reports, including DSURs, PBRERs, PSURs, PADERs, and IND Annual Reports, as applicable
- Contribute to safety-related regulatory documentation, including product labeling, Company Core Data Sheets (CCDS), Investigator Brochures, Integrated Summaries of Safety, clinical protocols, and informed consent documents
- Support responses to regulatory authority inquiries and participate in safety governance discussions to inform product-level decisions
- Develop and refine risk management strategies across development and post-approval settings, ensuring alignment with evolving regulatory expectations
Cross-Functional Collaboration & Organizational Leadership
- Act as a trusted medical safety partner to Clinical Development, Regulatory Affairs, Medical Affairs, and other key stakeholders, influencing decisions that impact product safety and patient care
- Represent Drug Safety on multidisciplinary teams, contributing to clinical research strategies, development plans, and ongoing product lifecycle activities
- Provide leadership in strengthening safety surveillance processes, operational practices, and organizational capabilities
- Mentor and guide safety professionals and cross-functional colleagues, with potential responsibility for direct reports and resource management
Requirements:
- M.D. degree plus accredited residency in a relevant clinical specialty (e.g., Internal Medicine, Family Practice, Neurology)
- Board certification and clinical/industry experience required
- 4+ years of relevant experience
- Experience in pharmacovigilance in a pharmaceutical (preferably) or biotechnology company, with experience in signal management (e.g., signal detection, evaluation, assessment)
- Recognized thought leader with deep medical and scientific expertise and comprehensive knowledge of pharmacovigilance, safety surveillance, and risk management
- Demonstrated ability to evaluate complex safety data, apply sound medical judgment, and develop practical strategies to address emerging safety concerns
- Strong strategic thinking and problem-solving skills, with the ability to translate scientific insights into actionable recommendations and business decisions
- Proven ability to influence senior leaders and cross-functional stakeholders while
#LI-KM1
Neurocrine Biosciences is an EEO/Disability/Vets employer.
We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.
_
The annual base salary we reasonably expect to pay is $292,600.00-$399,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 35% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.Who We Are:
Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. (*in collaboration with AbbVie)
About the Role:
In this highly visible role, you will serve as a strategic medical safety leader, providing expert medical oversight of our evolving pipeline and safety profiles driving proactive benefit-risk management throughout the product lifecycle.You will partner closely with senior leaders across Drug Safety, Clinical Development, Regulatory Affairs, Medical Affairs, and other cross-functional teams to translate complex safety data into actionable insights, inform critical decisions, and ensure a comprehensive, science-driven approach to patient safety.
This opportunity is well suited for a physician with strong pharmacovigilance expertise who enjoys balancing hands-on medical and scientific evaluation with strategic leadership, cross-functional influence, and meaningful product ownership.
_
Your Contributions (include, but are not limited to):
Product Safety Strategy & Medical Leadership
- Serve as the medical safety expert for assigned marketed and/or investigational therapies, with accountability for the ongoing evaluation and management of their safety profiles
- Lead the development and execution of global safety surveillance and risk management strategies, ensuring proactive identification, assessment, and mitigation of emerging safety concerns
- Provide strategic medical guidance to senior leadership and cross-functional governance teams on safety-related decisions, evolving benefit-risk considerations, and product lifecycle management
- Drive safety strategy and decision-making through the interpretation of complex clinical and post-marketing safety data
Pharmacovigilance & Signal Management
- Provide medical guidance for signal detection, evaluation, assessment, and management activities, including the investigation of emerging safety trends and potential risks
- Lead aggregate safety data reviews and provide medical interpretation to support ongoing safety surveillance and benefit-risk evaluations
- Oversee and contribute to the medical review of individual case safety reports, including seriousness, expectedness, causality assessments, and clinical interpretation, as needed
- Partner with pharmacovigilance and safety operations teams to ensure robust, compliant, and scientifically sound safety surveillance practices
Regulatory Strategy & Safety Governance
- Provide medical oversight and strategic input into safety-related regulatory submissions and periodic safety reports, including DSURs, PBRERs, PSURs, PADERs, and IND Annual Reports, as applicable
- Contribute to safety-related regulatory documentation, including product labeling, Company Core Data Sheets (CCDS), Investigator Brochures, Integrated Summaries of Safety, clinical protocols, and informed consent documents
- Support responses to regulatory authority inquiries and participate in safety governance discussions to inform product-level decisions
- Develop and refine risk management strategies across development and post-approval settings, ensuring alignment with evolving regulatory expectations
Cross-Functional Collaboration & Organizational Leadership
- Act as a trusted medical safety partner to Clinical Development, Regulatory Affairs, Medical Affairs, and other key stakeholders, influencing decisions that impact product safety and patient care
- Represent Drug Safety on multidisciplinary teams, contributing to clinical research strategies, development plans, and ongoing product lifecycle activities
- Provide leadership in strengthening safety surveillance processes, operational practices, and organizational capabilities
- Mentor and guide safety professionals and cross-functional colleagues, with potential responsibility for direct reports and resource management
Requirements:
- M.D. degree plus accredited residency in a relevant clinical specialty (e.g., Internal Medicine, Family Practice, Neurology)
- Board certification and clinical/industry experience required
- 4+ years of relevant experience
- Experience in pharmacovigilance in a pharmaceutical (preferably) or biotechnology company, with experience in signal management (e.g., signal detection, evaluation, assessment)
- Recognized thought leader with deep medical and scientific expertise and comprehensive knowledge of pharmacovigilance, safety surveillance, and risk management
- Demonstrated ability to evaluate complex safety data, apply sound medical judgment, and develop practical strategies to address emerging safety concerns
- Strong strategic thinking and problem-solving skills, with the ability to translate scientific insights into actionable recommendations and business decisions
- Proven ability to influence senior leaders and cross-functional stakeholders while
#LI-KM1
Neurocrine Biosciences is an EEO/Disability/Vets employer.
We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description.
_
The annual base salary we reasonably expect to pay is $292,600.00-$399,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 35% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.See All 295+ Safety Director Jobs
Find roles that match your experience and apply in just a few clicks.
Find Safety Director JobsSafety Director Job Market
Who's Hiring
- IQVIA12
- Regeneron10
- AbbVie9
- AstraZeneca4
- Boar's Head3
Top Industries Hiring
- Biotechnology & Pharmaceuticals
- Healthcare & Medical Services
- Consulting & Professional Services
- Medical Devices
- Science & Research
What Employers Look For
The qualifications that appear most often in safety director jobs.
- 7 or more years of progressive EHS or occupational safety experience
- OSHA 30-hour certification or Certified Safety Professional credential
- Demonstrated experience managing injury and illness recordkeeping programs
- Bachelor's degree in occupational safety, industrial hygiene, or a related field
- Experience conducting incident investigations and root-cause analysis
- Proficiency with safety management software and regulatory reporting systems
Tips for Your Safety Director Job Search
Tailor your resume to the industry
Safety director roles in construction read very differently from those in healthcare or chemical manufacturing. Reframe your resume for each sector, foregrounding the specific regulatory frameworks, incident types, and workforce sizes you managed rather than listing generic safety tasks.
Certify before you apply to senior roles
Many director-level postings screen for CSP, CHMM, or CHST credentials before interviews are granted. If you hold one, put it immediately after your name in your header so it clears applicant tracking filters before a human ever reads your resume.
Quantify your safety record precisely
Hiring managers want to see your TRIR and DART rate reductions, not vague claims of improvement. State the baseline, the period, and the outcome you drove, then connect it to the workforce size so the scale of the achievement is immediately clear.
Apply early to roles that fit
Migrate Mate lists safety director openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Prepare for scenario-based interview rounds
Safety director interviews often include a fatality or near-miss scenario where you walk through your investigation process live. Practice articulating root-cause analysis methods, corrective action hierarchies, and how you communicate findings to executive leadership under time pressure.
Negotiate scope, not just salary
When an offer arrives, clarify reporting structure, budget authority, and headcount before accepting. Directors who later find they lack purchasing authority for safety equipment or cannot hire their own coordinators face the same constraints as managers, regardless of their title.
Safety Director Jobs: Frequently Asked Questions
Which companies are hiring the most safety directors?
IQVIA, Regeneron, and AbbVie are hiring the most safety directors right now, with openings concentrated in California, New Jersey, and New York, based on current listings on Migrate Mate as of November 2026. Construction, manufacturing, and healthcare employers account for the largest share of active postings.
How many safety director jobs are remote?
About 63% of safety director openings are fully remote or hybrid as of November 2026, though fully remote arrangements are far more common in corporate EHS program management than in plant, site, or field-based safety roles, where physical presence is a core requirement of the job.
How do you become a safety director?
Start with a degree in occupational safety, industrial hygiene, or environmental science, then build field experience as a safety coordinator or EHS specialist. Earning a Certified Safety Professional credential strengthens your candidacy for director-level roles. Most employers expect demonstrated experience managing safety programs, leading investigations, and presenting to senior leadership before promoting or hiring at the director level.
Can you get hired as a safety director without direct director experience?
Yes, but you'll need a strong substitute for the title itself. Employers hiring first-time directors typically accept candidates who led safety programs for a business unit, managed a team of safety professionals, or drove measurable reductions in recordable incident rates. Focus your resume on scope, decision-making authority, and outcomes rather than job titles held.
What does the safety director interview process look like?
Most safety director processes run three to four rounds. An initial phone screen with HR is followed by a technical interview covering regulatory knowledge, incident investigation methodology, and program design. Finalists typically present to a panel that includes operations leadership and sometimes legal or HR. Scenario-based questions about fatalities, citations, or program failures are common at the final stage.
Where can I find and apply to safety director jobs?
You can find and apply to safety director jobs on Migrate Mate, which lists current openings from across the United States. Search for roles that match your industry background and experience level, then apply directly to each listing that fits.
See All 295+ Safety Director Jobs
Find roles that match your experience and apply in just a few clicks.
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