Senior AI Product Manager Jobs in Illinois
Senior AI Product Manager jobs in Illinois are open across Chicago, Bolingbrook, and Oak Brook and other Illinois metros, with employers like CCC Intelligent Solutions, Bmo Bank N.A. (Formerly Known As Bmo Harris Bank N.A.), and Chamberlain hiring at every experience level. Find a role that fits below and apply directly.
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INTRODUCTION
Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
ABOUT THE ROLE
Passionate about making a difference in the world of cancer genomics? With the advent of genomic sequencing, we can finally decode and process our genetic makeup. We now have more data than ever before but providers don't have the infrastructure or expertise to make sense of this data. We’re on a mission to connect an entire ecosystem to redefine how genomic data is used in clinical settings.
We are looking for a highly motivated and capable technical product manager with extensive experience and interest in translational cancer research, diagnostic test development, and systems validation and verification. This position requires experience with diagnostic products, clinical regulatory requirements for software systems, and algorithms development. Top candidates will also have significant experience in regulated device development. This role will report to the head of Bioinformatics and support software product development functions.
Responsibilities:
- Managing software development lifecycle processes.
- Engaging with the quality and regulatory team and supporting quality processes.
- Incident management: Promptly triage, coordinate, and manage the resolution of issues.
- Stakeholder support: Provide dedicated and responsive support to all stakeholders using the bioinformatics software.
- Feature request intake and prioritization: Collect, prioritize, and manage feature requests to guide software development.
- Interfacing with Product Managers of downstream engineering teams during implementation.
- Data contract management with downstream engineering teams.
- Documentation: Maintain comprehensive and up-to-date documentation for all bioinformatics software.
REQUIRED EXPERIENCE:
- Bachelors or M.S. in a scientific discipline
- Significant experience in medical device development and regulatory submission
- 2-4 years relevant experience in diagnostics product development
- Familiarity with US FDA and EU IVDR regulatory frameworks.
PREFERRED QUALIFICATIONS:
- A track record of successful submissions to US and international regulatory agencies
- Experience in cancer genetics, immunology, or molecular biology
- Experience working with next-generation sequencing data
- Self-driven and works well in interdisciplinary teams
- Experience with communicating insights and presenting concepts to a diverse audience
COMPENSATION
- Salary Range: $110,000-$160,000
The expected salary range above is applicable if the role is performed from Illinois and may vary for other locations (California, Colorado, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
See All 11 Senior AI Product Manager Jobs in Illinois
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Find JobsSenior AI Product Manager Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Senior AI Product Manager Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
Who's Hiring
- CCC Intelligent Solutions2

- Bmo Bank N.A. (Formerly Known As Bmo Harris Bank N.A.)1

- Chamberlain1

- EY1

- Euromarket Designs, Inc. (D/B/A Crate & Barrel And Cb2)1

Top Industries Hiring
- Technology & Software4
- Accounting & Auditing1
- Banking & Financial Services1
- Biotechnology & Pharmaceuticals1
- Consulting & Professional Services1
What Illinois Employers Look For
The qualifications that appear most often in senior AI product manager jobs across Illinois.
- 5+ years of product management experience with at least 2 years on AI or ML products
- Demonstrated experience shipping production AI features, models, or platforms to real users
- Ability to write and interpret technical specifications alongside machine learning engineers
- Proficiency with product analytics tools and model performance evaluation frameworks
- Experience working cross-functionally with data science, MLOps, and design teams
- Bachelor's degree in computer science, engineering, or a related technical field
Senior AI Product Manager Jobs in Illinois: Frequently Asked Questions
How many senior AI product manager jobs are there in Illinois?
There are 11+ senior AI product manager openings in Illinois on Migrate Mate as of June 2026, with the most roles in Chicago, Illinois, and Bolingbrook. New positions post regularly as employers across Illinois hire.
Which Illinois cities have the most senior AI product manager jobs?
Chicago, Illinois, and Bolingbrook have the most senior AI product manager openings in Illinois right now, with additional roles spread across smaller metros statewide.
Which companies hire senior AI product managers in Illinois?
Employers hiring senior AI product managers in Illinois include CCC Intelligent Solutions, Bmo Bank N.A. (Formerly Known As Bmo Harris Bank N.A.), and Chamberlain, based on current listings on Migrate Mate as of June 2026.
Are there remote senior AI product manager jobs in Illinois?
Yes. About 64% of senior AI product manager openings tied to Illinois are remote or hybrid as of June 2026. The rest are on-site roles based in Illinois metros.
How do I apply for senior AI product manager jobs in Illinois?
You can apply to senior AI product manager jobs in Illinois directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Illinois location, then apply to each one that fits.
See All 11 Senior AI Product Manager Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
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